About Enhancer

Enhancer ID: E_02_0370
Species: human
Position : chr12:102393416-102395416
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Perinatal mycoplasma infection
Pubmed ID:  32615080
Enhancer experiment: Immunostaining?RT-qPCR?Western blotting
Enhancer experiment description: Azithromycin disturbed hepatocyte differentiation, maturation and metabolic function via upregulating GR-C/EBP? signal and reducing the expression and secretion levels of IGF1 in HepG2 cells.

About Target gene

Target gene : IGF1
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: Azithromycin disturbed hepatocyte differentiation, maturation and metabolic function via upregulating GR-C/EBP? signal and reducing the expression and secretion levels of IGF1 in HepG2 cells.

About TF

TF name : --
TF experiment: Immunostaining?RT-qPCR?Western blotting
TF experiment description: Azithromycin disturbed hepatocyte differentiation, maturation and metabolic function via upregulating GR-C/EBP? signal and reducing the expression and secretion levels of IGF1 in HepG2 cells.

About Function

Enhancer function : Azithromycin disturbed hepatocyte differentiation, maturation and metabolic function via upregulating GR-C/EBP? signal and reducing the expression and secretion levels of IGF1 in HepG2 cells.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:		 Azithromycin disturbed hepatocyte differentiation, maturation and metabolic function via upregulating GR-C/EBP? signal and reducing the expression and secretion levels of IGF1 in HepG2 cells.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer

Enhancer associated SNPs