About Enhancer
| Enhancer ID: | E_02_0409 |
| Species: | human |
| Position : | chr22:19327664-19329664   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Nothing |
| Pubmed ID: | 30285846 |
| Enhancer experiment: | Co-immunoprecipitation?GST pull-down assays?Immunofluorescence?ChIP-qPCR?ChIP-seq?RNA preparation, RT-qPCR and poly(A) RNA-seq |
| Enhancer experiment description: | Together, our results provide novel insights into the mechanism by which the HIRA complex specificallyrecognizes and deposits H3.3 at promoters and enhancers of developmental genes, which plays a critical role in neural differentiation of mES cells. |
About Target gene
| Target gene : | HIRA |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Together, our results provide novel insights into the mechanism by which the HIRA complex specificallyrecognizes and deposits H3.3 at promoters and enhancers of developmental genes, which plays a critical role in neural differentiation of mES cells. |
About TF
| TF name : | -- |
| TF experiment: | Co-immunoprecipitation?GST pull-down assays?Immunofluorescence?ChIP-qPCR?ChIP-seq?RNA preparation, RT-qPCR and poly(A) RNA-seq |
| TF experiment description: | Together, our results provide novel insights into the mechanism by which the HIRA complex specificallyrecognizes and deposits H3.3 at promoters and enhancers of developmental genes, which plays a critical role in neural differentiation of mES cells. |
About Function
| Enhancer function : | Together, our results provide novel insights into the mechanism by which the HIRA complex specificallyrecognizes and deposits H3.3 at promoters and enhancers of developmental genes, which plays a critical role in neural differentiation of mES cells. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Together, our results provide novel insights into the mechanism by which the HIRA complex specificallyrecognizes and deposits H3.3 at promoters and enhancers of developmental genes, which plays a critical role in neural differentiation of mES cells. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene