About Enhancer

Enhancer ID: E_02_0422
Species: human
Position : chr6:31572964-31574964
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Hepatocellular carcinoma, tumour
Pubmed ID:  30214582
Enhancer experiment: Immunohistochemistry (IHC), Weston blot
Enhancer experiment description: The activation of NF-?B promotes tumor necrosis factor (TNF)-? to produce VEGF and positively regulate the expression of mRNA and proteins in the VEGF pathway (21).

About Target gene

Target gene : TNF
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: The activation of NF-?B promotes tumor necrosis factor (TNF)-? to produce VEGF and positively regulate the expression of mRNA and proteins in the VEGF pathway (21).

About TF

TF name : --
TF experiment: ????(IHC),weston blot
TF experiment description: The activation of NF-?B promotes tumor necrosis factor (TNF)-? to produce VEGF and positively regulate the expression of mRNA and proteins in the VEGF pathway (21).

About Function

Enhancer function : The activation of NF-?B promotes tumor necrosis factor (TNF)-? to produce VEGF and positively regulate the expression of mRNA and proteins in the VEGF pathway (21).
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
The activation of NF-?B promotes tumor necrosis factor (TNF)-? to produce VEGF and positively regulate the expression of mRNA and proteins in the VEGF pathway (21).

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs