About Enhancer
| Enhancer ID: | E_02_0425 |
| Species: | human |
| Position : | chr20:6765006-6767006   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30206934 |
| Enhancer experiment: | RT?PCR |
| Enhancer experiment description: | Not only gene expression was affected, tension force was also able to induce ATP release, which subse- quently could promote osteogenesis by osteoblasts (Kariya et al., 2015; Sun et al., 2013). This promoting effect was proposed to be due to a stimulated expression of BMP2, 4, and 5 (Ayala Pea, Scolaro, &Santilln, 2013). |
About Target gene
| Target gene : | BMP2 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Not only gene expression was affected, tension force was also able to induce ATP release, which subse- quently could promote osteogenesis by osteoblasts (Kariya et al., 2015; Sun et al., 2013). This promoting effect was proposed to be due to a stimulated expression of BMP2, 4, and 5 (Ayala Pea, Scolaro, &Santilln, 2013). |
About TF
| TF name : | -- |
| TF experiment: | RT?PCR |
| TF experiment description: | Not only gene expression was affected, tension force was also able to induce ATP release, which subse- quently could promote osteogenesis by osteoblasts (Kariya et al., 2015; Sun et al., 2013). This promoting effect was proposed to be due to a stimulated expression of BMP2, 4, and 5 (Ayala Pea, Scolaro, &Santilln, 2013). |
About Function
| Enhancer function : | Not only gene expression was affected, tension force was also able to induce ATP release, which subse- quently could promote osteogenesis by osteoblasts (Kariya et al., 2015; Sun et al., 2013). This promoting effect was proposed to be due to a stimulated expression of BMP2, 4, and 5 (Ayala Pea, Scolaro, &Santilln, 2013). |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Not only gene expression was affected, tension force was also able to induce ATP release, which subse- quently could promote osteogenesis by osteoblasts (Kariya et al., 2015; Sun et al., 2013). This promoting effect was proposed to be due to a stimulated expression of BMP2, 4, and 5 (Ayala Pea, Scolaro, &Santilln, 2013). |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene