About Enhancer
| Enhancer ID: | E_02_0430 |
| Species: | human |
| Position : | chr18:55219748-55221748   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Colorectal cancer, adenomatous colorectal polyposis |
| Pubmed ID: | 30200414 |
| Enhancer experiment: | ChIP-seq,qRT-PCR,weston blot |
| Enhancer experiment description: | Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells.However, in human cells, the TCF4 role is redundant with the related T-cell factor 1 (TCF1) and lymphoid enhancer-binding factor 1 (LEF1) transcription factors. |
About Target gene
| Target gene : | TCF4(5730422P05Rik,ASP-I2,E2-2,E2.2,ITF-2,ITF-2b,ITF2,ME2,MITF-2A,MITF-2B,SEF-2,SEF2,SEF2-1,TFE,Tcf-4,bHLHb19),LEF1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells.However, in human cells, the TCF4 role is redundant with the related T-cell factor 1 (TCF1) and lymphoid enhancer-binding factor 1 (LEF1) transcription factors. ;Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells.However, in human cells, the TCF4 role is redundant with the related T-cell factor 1 (TCF1) and lymphoid enhancer-binding factor 1 (LEF1) transcription factors. |
About TF
| TF name : | -- |
| TF experiment: | ChIP-seq,qRT-PCR,weston blot |
| TF experiment description: | Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells.However, in human cells, the TCF4 role is redundant with the related T-cell factor 1 (TCF1) and lymphoid enhancer-binding factor 1 (LEF1) transcription factors. ;Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells.However, in human cells, the TCF4 role is redundant with the related T-cell factor 1 (TCF1) and lymphoid enhancer-binding factor 1 (LEF1) transcription factors. |
About Function
| Enhancer function : | Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells.However, in human cells, the TCF4 role is redundant with the related T-cell factor 1 (TCF1) and lymphoid enhancer-binding factor 1 (LEF1) transcription factors. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Wnt Effector TCF4 Is Dispensable for Wnt Signaling in Human Cancer Cells.However, in human cells, the TCF4 role is redundant with the related T-cell factor 1 (TCF1) and lymphoid enhancer-binding factor 1 (LEF1) transcription factors. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene