About Enhancer

Enhancer ID: E_02_0452
Species: human
Position : chr8:22111886-22113886
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: --
Pubmed ID:  30151761
Enhancer experiment: PCR, gene knockdown
Enhancer experiment description: Prior to the genome editing era, the conventional knock-in strategy based on homologous recombination (HR) was the only option avail- able, but it had limitations in mouse embryonic stem cells because intrinsic HR at a target site occurs with extremely low frequency in somatic cells.

About Target gene

Target gene : HR
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: Prior to the genome editing era, the conventional knock-in strategy based on homologous recombination (HR) was the only option avail- able, but it had limitations in mouse embryonic stem cells because intrinsic HR at a target site occurs with extremely low frequency in somatic cells.

About TF

TF name : --
TF experiment: PCR,????
TF experiment description: Prior to the genome editing era, the conventional knock-in strategy based on homologous recombination (HR) was the only option avail- able, but it had limitations in mouse embryonic stem cells because intrinsic HR at a target site occurs with extremely low frequency in somatic cells.

About Function

Enhancer function : Prior to the genome editing era, the conventional knock-in strategy based on homologous recombination (HR) was the only option avail- able, but it had limitations in mouse embryonic stem cells because intrinsic HR at a target site occurs with extremely low frequency in somatic cells.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
Prior to the genome editing era, the conventional knock-in strategy based on homologous recombination (HR) was the only option avail- able, but it had limitations in mouse embryonic stem cells because intrinsic HR at a target site occurs with extremely low frequency in somatic cells.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs