About Enhancer

Enhancer ID: E_02_0455
Species: human
Position : chr6:41733756-41735756
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Obesity
Pubmed ID:  30148699
Enhancer experiment: PCR, statistical analysis
Enhancer experiment description: However, the levels of other mitochon- drial transcription factors (mtTF) such as PPAR-c coactivator (PGC)-1a and mtTFA were decreased by 32% and 35%, re- spectively, relative to untreated 3T3-L1 cells, although only the latter was statistically significant (Fig. 5B D).

About Target gene

Target gene : PGC
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: However, the levels of other mitochon- drial transcription factors (mtTF) such as PPAR-c coactivator (PGC)-1a and mtTFA were decreased by 32% and 35%, re- spectively, relative to untreated 3T3-L1 cells, although only the latter was statistically significant (Fig. 5B D).

About TF

TF name : --
TF experiment: PCR,????
TF experiment description: However, the levels of other mitochon- drial transcription factors (mtTF) such as PPAR-c coactivator (PGC)-1a and mtTFA were decreased by 32% and 35%, re- spectively, relative to untreated 3T3-L1 cells, although only the latter was statistically significant (Fig. 5B D).

About Function

Enhancer function : However, the levels of other mitochon- drial transcription factors (mtTF) such as PPAR-c coactivator (PGC)-1a and mtTFA were decreased by 32% and 35%, re- spectively, relative to untreated 3T3-L1 cells, although only the latter was statistically significant (Fig. 5B D).
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
However, the levels of other mitochon- drial transcription factors (mtTF) such as PPAR-c coactivator (PGC)-1a and mtTFA were decreased by 32% and 35%, re- spectively, relative to untreated 3T3-L1 cells, although only the latter was statistically significant (Fig. 5B D).

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs