About Enhancer
| Enhancer ID: | E_02_0465 |
| Species: | human |
| Position : | chr8:132864317-132866317   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Non alcoholic fatty liver disease (naf ld), liver fibrosis, cirrhosis, hepatocellular carcinoma |
| Pubmed ID: | 30135326 |
| Enhancer experiment: | QPCR, ELISA, Weston blot, statistical analysis |
| Enhancer experiment description: | Rg1 significantly reduced liver weight, serum alanine aminotransferase (A LT), aspartate aminotransferase (AST), triglyceride (TG), liver fr ee fatty acids (FFAs) and malondialdehyde (MDA) levels, and increased superoxide dismutase (SOD) activity. |
About Target gene
| Target gene : | TG |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Rg1 significantly reduced liver weight, serum alanine aminotransferase (A LT), aspartate aminotransferase (AST), triglyceride (TG), liver fr ee fatty acids (FFAs) and malondialdehyde (MDA) levels, and increased superoxide dismutase (SOD) activity. |
About TF
| TF name : | -- |
| TF experiment: | qPCR,ELISA,weston blot,???? |
| TF experiment description: | Rg1 significantly reduced liver weight, serum alanine aminotransferase (A LT), aspartate aminotransferase (AST), triglyceride (TG), liver fr ee fatty acids (FFAs) and malondialdehyde (MDA) levels, and increased superoxide dismutase (SOD) activity. |
About Function
| Enhancer function : | Rg1 significantly reduced liver weight, serum alanine aminotransferase (A LT), aspartate aminotransferase (AST), triglyceride (TG), liver fr ee fatty acids (FFAs) and malondialdehyde (MDA) levels, and increased superoxide dismutase (SOD) activity. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Rg1 significantly reduced liver weight, serum alanine aminotransferase (A LT), aspartate aminotransferase (AST), triglyceride (TG), liver fr ee fatty acids (FFAs) and malondialdehyde (MDA) levels, and increased superoxide dismutase (SOD) activity. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene