About Enhancer
Enhancer ID: |
E_02_0484 |
Species: |
human |
Position :
|
chr14:100776331-100778331 |
Biosample name: |
|
Experiment class :
|
High+Lowthroughput |
Enhancer type: |
Enhancer |
Disease: |
-- |
Pubmed ID: |
30103943
|
Enhancer experiment: |
Gene knockdown, fish, QRT PCR, Weston blot, chromatin immunoprecipitation (chip) - PCR assay, statistical analysis |
Enhancer experiment description: |
Knockdown studies of MEG3 and EZH2 by siRNA showed that MEG3/EZH2 negatively regulated osteo- genesis of hDFSCs. |
About Target gene
Target gene : |
MEG3(2900016C05Rik,3110050O07Rik,6330408G06Rik,AI425946,AW108224,D12Bwg1266e,Gtl2,R74756,R75394),EZH2 |
Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
Less strong evidence: |
RNA-Seq |
Target gene experiment description: |
Knockdown studies of MEG3 and EZH2 by siRNA showed that MEG3/EZH2 negatively regulated osteo- genesis of hDFSCs.;Knockdown studies of MEG3 and EZH2 by siRNA showed that MEG3/EZH2 negatively regulated osteo- genesis of hDFSCs. |
About TF
TF name : |
-- |
TF experiment: |
????,FISH, qRT-PCR,weston blot,Chromatin immunoprecipitation (ChIP)-PCR assay,???? |
TF experiment description: |
Knockdown studies of MEG3 and EZH2 by siRNA showed that MEG3/EZH2 negatively regulated osteo- genesis of hDFSCs.;Knockdown studies of MEG3 and EZH2 by siRNA showed that MEG3/EZH2 negatively regulated osteo- genesis of hDFSCs. |
About Function
Enhancer function : |
Knockdown studies of MEG3 and EZH2 by siRNA showed that MEG3/EZH2 negatively regulated osteo- genesis of hDFSCs. |
Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function experiment description: |
Knockdown studies of MEG3 and EZH2 by siRNA showed that MEG3/EZH2 negatively regulated osteo- genesis of hDFSCs. |
About SNP
Upstream Pathway Annotation of TF
GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs