About Enhancer
| Enhancer ID: | E_02_0491 |
| Species: | human |
| Position : | chr19:19142788-19144788   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30085311 |
| Enhancer experiment: | Real time PCR, IGF-1 enzyme linked immunosorbent assay, Western blot, and statistical analysis |
| Enhancer experiment description: | Broiler growth is related to skeletal muscle develop- ment which is regulated by myogenic regulatory factors including myogenic differentiation factor 1 (MyoD1), myogenic factor 5 (Myf5), muscle regulator 4 (MRF4), myogenin (MyoG), myocyte enhancer factor 2 family of transcription factors (MEF2A, B, C, D), as well as myostatin (MSTN) (Hennebry et al., 2009; Townley-Tilson et al., 2010). |
About Target gene
| Target gene : | MEF2B,Myf5 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Broiler growth is related to skeletal muscle develop- ment which is regulated by myogenic regulatory factors including myogenic differentiation factor 1 (MyoD1), myogenic factor 5 (Myf5), muscle regulator 4 (MRF4), myogenin (MyoG), myocyte enhancer factor 2 family of transcription factors (MEF2A, B, C, D), as well as myostatin (MSTN) (Hennebry et al., 2009; Townley-Tilson et al., 2010). ;Broiler growth is related to skeletal muscle develop- ment which is regulated by myogenic regulatory factors including myogenic differentiation factor 1 (MyoD1), myogenic factor 5 (Myf5), muscle regulator 4 (MRF4), myogenin (MyoG), myocyte enhancer factor 2 family of transcription factors (MEF2A, B, C, D), as well as myostatin (MSTN) (Hennebry et al., 2009; Townley-Tilson et al., 2010). |
About TF
| TF name : | -- |
| TF experiment: | real-time PCR,IGF-1 Enzyme-Linked Immunosorbent Assay,western blot,???? |
| TF experiment description: | Broiler growth is related to skeletal muscle develop- ment which is regulated by myogenic regulatory factors including myogenic differentiation factor 1 (MyoD1), myogenic factor 5 (Myf5), muscle regulator 4 (MRF4), myogenin (MyoG), myocyte enhancer factor 2 family of transcription factors (MEF2A, B, C, D), as well as myostatin (MSTN) (Hennebry et al., 2009; Townley-Tilson et al., 2010). ;Broiler growth is related to skeletal muscle develop- ment which is regulated by myogenic regulatory factors including myogenic differentiation factor 1 (MyoD1), myogenic factor 5 (Myf5), muscle regulator 4 (MRF4), myogenin (MyoG), myocyte enhancer factor 2 family of transcription factors (MEF2A, B, C, D), as well as myostatin (MSTN) (Hennebry et al., 2009; Townley-Tilson et al., 2010). |
About Function
| Enhancer function : | Broiler growth is related to skeletal muscle develop- ment which is regulated by myogenic regulatory factors including myogenic differentiation factor 1 (MyoD1), myogenic factor 5 (Myf5), muscle regulator 4 (MRF4), myogenin (MyoG), myocyte enhancer factor 2 family of transcription factors (MEF2A, B, C, D), as well as myostatin (MSTN) (Hennebry et al., 2009; Townley-Tilson et al., 2010). |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Broiler growth is related to skeletal muscle develop- ment which is regulated by myogenic regulatory factors including myogenic differentiation factor 1 (MyoD1), myogenic factor 5 (Myf5), muscle regulator 4 (MRF4), myogenin (MyoG), myocyte enhancer factor 2 family of transcription factors (MEF2A, B, C, D), as well as myostatin (MSTN) (Hennebry et al., 2009; Townley-Tilson et al., 2010). |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene