About Enhancer
| Enhancer ID: | E_02_0529 |
| Species: | human |
| Position : | chr13:27917694-27919694   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Pancreatic ductal adenocarcinoma (pda) |
| Pubmed ID: | 30010625 |
| Enhancer experiment: | Immunohistochemistry,ChIP-seq,RT-PCR,ChIP qPCR |
| Enhancer experiment description: | BRG1 bound to regions of the Sox9 promoter to regulate its expression and was critical for recruitment of upstream regulators, including PDX1, to the Sox9 promoter and enhancer in acinar cells. |
About Target gene
| Target gene : | PDX1(IDX-1,IPF-1,Ipf1,Mody4,STF-1,pdx-1),SOX9(CMD1,CMPD1,SRA1,SRXX2,SRXY10) |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | BRG1 bound to regions of the Sox9 promoter to regulate its expression and was critical for recruitment of upstream regulators, including PDX1, to the Sox9 promoter and enhancer in acinar cells. ;BRG1 bound to regions of the Sox9 promoter to regulate its expression and was critical for recruitment of upstream regulators, including PDX1, to the Sox9 promoter and enhancer in acinar cells. |
About TF
| TF name : | -- |
| TF experiment: | Immunohistochemistry,ChIP-seq,RT-PCR,ChIP qPCR |
| TF experiment description: | BRG1 bound to regions of the Sox9 promoter to regulate its expression and was critical for recruitment of upstream regulators, including PDX1, to the Sox9 promoter and enhancer in acinar cells. ;BRG1 bound to regions of the Sox9 promoter to regulate its expression and was critical for recruitment of upstream regulators, including PDX1, to the Sox9 promoter and enhancer in acinar cells. |
About Function
| Enhancer function : | BRG1 bound to regions of the Sox9 promoter to regulate its expression and was critical for recruitment of upstream regulators, including PDX1, to the Sox9 promoter and enhancer in acinar cells. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
BRG1 bound to regions of the Sox9 promoter to regulate its expression and was critical for recruitment of upstream regulators, including PDX1, to the Sox9 promoter and enhancer in acinar cells. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene