About Enhancer
| Enhancer ID: | E_02_0572 |
| Species: | human |
| Position : | chr10:86432735-86434735   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 33318687 |
| Enhancer experiment: | Plasmid construction, gene targeting, Western blot, GFP quantification and cell cycle analysis, cell proliferation analysis, immunofluorescence staining, alkaline phosphatase staining, single cell colony formation assay, RT qPCR, chip SEQ riboprobes, TT SEQ, ATAC SEQ, chip SEQ analysis, ATAC SEQ analysis |
| Enhancer experiment description: | We report that the cohesin release factor WAPL creates a pool of free cohesin, in a process known as cohesin turnover, which reloads it to cell-type specific binding sites. |
About Target gene
| Target gene : | WAPL |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | We report that the cohesin release factor WAPL creates a pool of free cohesin, in a process known as cohesin turnover, which reloads it to cell-type specific binding sites. |
About TF
| TF name : | -- |
| TF experiment: | ????????????????GFP??????????????????????????????????????????RT-qPCR?ChIP-seq???????TT-seq?ATAC-seq?ChIP-seq ???ATAC-seq Analysis |
| TF experiment description: | We report that the cohesin release factor WAPL creates a pool of free cohesin, in a process known as cohesin turnover, which reloads it to cell-type specific binding sites. |
About Function
| Enhancer function : | We report that the cohesin release factor WAPL creates a pool of free cohesin, in a process known as cohesin turnover, which reloads it to cell-type specific binding sites. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
We report that the cohesin release factor WAPL creates a pool of free cohesin, in a process known as cohesin turnover, which reloads it to cell-type specific binding sites. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene