About Enhancer
| Enhancer ID: | E_02_0603 |
| Species: | human |
| Position : | chr9:107482552-107484552   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 33033262 |
| Enhancer experiment: | IPSC generation and EPISC to naive PSC transition, plasmid and molecular cloning, ribonucleic acid isolation and RT qPCR, immunofluorescence, Western blot and co immunoprecipitation, flow cytometry analysis, ribonucleic acid sequencing and analysis, chip qPCR and chip SEQ, chip SEQ analysis, chip SEQ analysis, chip SEQ analysis, chip SEQ analysis |
| Enhancer experiment description: | Establishes a multifaceted role for JMJD3, placing it as a key partner of KLF4 and a scaffold that assists chromatin interactions and activates gene transcription. |
About Target gene
| Target gene : | KLF4(EZF,Gklf,Zie),SOX2(ANOP3,MCOPS3) |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Establishes a multifaceted role for JMJD3, placing it as a key partner of KLF4 and a scaffold that assists chromatin interactions and activates gene transcription.;JMJD3 also promotes enhancer-promoter looping through the cohesin loading factor NIPBL and ultimately transcriptional elongation. |
About TF
| TF name : | -- |
| TF experiment: | iPSC ??? EpiSC ??? PSC ??????????????????? RT-qPCR????????????????????????????????????ChIP-qPCR ? ChIP-seq?ChIP-seq ???ChIP-seq ???ChIP-seq ?? |
| TF experiment description: | Establishes a multifaceted role for JMJD3, placing it as a key partner of KLF4 and a scaffold that assists chromatin interactions and activates gene transcription.;JMJD3 also promotes enhancer-promoter looping through the cohesin loading factor NIPBL and ultimately transcriptional elongation. |
About Function
| Enhancer function : | Establishes a multifaceted role for JMJD3, placing it as a key partner of KLF4 and a scaffold that assists chromatin interactions and activates gene transcription. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Establishes a multifaceted role for JMJD3, placing it as a key partner of KLF4 and a scaffold that assists chromatin interactions and activates gene transcription. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene