About Enhancer
| Enhancer ID: | E_02_0610 |
| Species: | human |
| Position : | chr3:181709146-181711146   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Heart disease |
| Pubmed ID: | 31465963 |
| Enhancer experiment: | ChIP-seq,RNA-seq |
| Enhancer experiment description: | Enhancers of undifferentiated ESCs cooperatively regulate pluripotency genes, such as POU5F1/ OCT4, NANOG, and SOX2 (Table 1; Figure 6D), which are pluripo_x005f_x0002_tent master transcription factors that can bind enhancer elements and recruit Mediator to activate much of the gene expression program of pluripotent ESCs. |
About Target gene
| Target gene : | SOX2(ANOP3,MCOPS3),POU5F1(OCT3,OCT4,OTF-3,OTF3,OTF4,Oct-3,Oct-4),NANOG(NANOG) |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Enhancers of undifferentiated ESCs cooperatively regulate pluripotency genes, such as POU5F1/ OCT4, NANOG, and SOX2 (Table 1; Figure 6D), which are pluripo_x005f_x0002_tent master transcription factors that can bind enhancer elements and recruit Mediator to activate much of the gene expression program of pluripotent ESCs.;Enhancers of undifferentiated ESCs cooperatively regulate pluripotency genes, such as POU5F1/ OCT4, NANOG, and SOX2 (Table 1; Figure 6D), which are pluripo_x005f_x0002_tent master transcription factors that can bind enhancer elements and recruit Mediator to activate much of the gene expression program of pluripotent ESCs.;Enhancers of undifferentiated ESCs cooperatively regulate pluripotency genes, such as POU5F1/ OCT4, NANOG, and SOX2 (Table 1; Figure 6D), which are pluripo_x005f_x0002_tent master transcription factors that can bind enhancer elements and recruit Mediator to activate much of the gene expression program of pluripotent ESCs. |
About TF
| TF name : | -- |
| TF experiment: | ChIP-seq,RNA-seq |
| TF experiment description: | Enhancers of undifferentiated ESCs cooperatively regulate pluripotency genes, such as POU5F1/ OCT4, NANOG, and SOX2 (Table 1; Figure 6D), which are pluripo_x005f_x0002_tent master transcription factors that can bind enhancer elements and recruit Mediator to activate much of the gene expression program of pluripotent ESCs.;Enhancers of undifferentiated ESCs cooperatively regulate pluripotency genes, such as POU5F1/ OCT4, NANOG, and SOX2 (Table 1; Figure 6D), which are pluripo_x005f_x0002_tent master transcription factors that can bind enhancer elements and recruit Mediator to activate much of the gene expression program of pluripotent ESCs.;Enhancers of undifferentiated ESCs cooperatively regulate pluripotency genes, such as POU5F1/ OCT4, NANOG, and SOX2 (Table 1; Figure 6D), which are pluripo_x005f_x0002_tent master transcription factors that can bind enhancer elements and recruit Mediator to activate much of the gene expression program of pluripotent ESCs. |
About Function
| Enhancer function : | Enhancers of undifferentiated ESCs cooperatively regulate pluripotency genes, such as POU5F1/ OCT4, NANOG, and SOX2 (Table 1; Figure 6D), which are pluripo_x005f_x0002_tent master transcription factors that can bind enhancer elements and recruit Mediator to activate much of the gene expression program of pluripotent ESCs. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Enhancers of undifferentiated ESCs cooperatively regulate pluripotency genes, such as POU5F1/ OCT4, NANOG, and SOX2 (Table 1; Figure 6D), which are pluripo_x005f_x0002_tent master transcription factors that can bind enhancer elements and recruit Mediator to activate much of the gene expression program of pluripotent ESCs. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene