About Enhancer

Enhancer ID: E_02_0634
Species: human
Position : chr10:100732618-100734618
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: Breast cancer (breast cancer)
Pubmed ID:  31408468
Enhancer experiment: RNA-seq,ChIP-seq
Enhancer experiment description: In the distal regions (up and down) of ER? binding sites contained a canonical ERE and other motifs including PAX2, ESRRB, SF1, and AP1 motifs as the most highly enriched (p-value <10?30) cis-elements.

About Target gene

Target gene : PAX2,ESRRB,SF1
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: In the distal regions (up and down) of ER? binding sites contained a canonical ERE and other motifs including PAX2, ESRRB, SF1, and AP1 motifs as the most highly enriched (p-value <10?30) cis-elements.;In the distal regions (up and down) of ER? binding sites contained a canonical ERE and other motifs including PAX2, ESRRB, SF1, and AP1 motifs as the most highly enriched (p-value <10?30) cis-elements.;In the distal regions (up and down) of ER? binding sites contained a canonical ERE and other motifs including PAX2, ESRRB, SF1, and AP1 motifs as the most highly enriched (p-value <10?30) cis-elements.

About TF

TF name : --
TF experiment: RNA-seq,ChIP-seq
TF experiment description: In the distal regions (up and down) of ER? binding sites contained a canonical ERE and other motifs including PAX2, ESRRB, SF1, and AP1 motifs as the most highly enriched (p-value <10?30) cis-elements.;In the distal regions (up and down) of ER? binding sites contained a canonical ERE and other motifs including PAX2, ESRRB, SF1, and AP1 motifs as the most highly enriched (p-value <10?30) cis-elements.;In the distal regions (up and down) of ER? binding sites contained a canonical ERE and other motifs including PAX2, ESRRB, SF1, and AP1 motifs as the most highly enriched (p-value <10?30) cis-elements.

About Function

Enhancer function : In the distal regions (up and down) of ER? binding sites contained a canonical ERE and other motifs including PAX2, ESRRB, SF1, and AP1 motifs as the most highly enriched (p-value <10?30) cis-elements.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
In the distal regions (up and down) of ER? binding sites contained a canonical ERE and other motifs including PAX2, ESRRB, SF1, and AP1 motifs as the most highly enriched (p-value <10?30) cis-elements.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs