About Enhancer
| Enhancer ID: |
E_02_0670 |
| Species: |
mouse |
| Position :
|
chr6:118561329-118563329
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Heart diseases |
| Pubmed ID: |
32308692
|
| Enhancer experiment: |
qRT-PCR,Western blotting,flow cytometry |
| Enhancer experiment description: |
Both knockdown of hypoxia inducible factor 1? (HIF-1?) and inactivation of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF?B) pathway inhibited over-expression of miR-711. |
About Target gene
| Target gene : |
Cacna1c(CACH2,CACN2,CACNL1A1,CCHL1A1,CaV1.2,LQT8,TS,TS.LQT8),FGF14 |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Both knockdown of hypoxia inducible factor 1? (HIF-1?) and inactivation of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF?B) pathway inhibited over-expression of miR-711.;Both knockdown of hypoxia inducible factor 1? (HIF-1?) and inactivation of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF?B) pathway inhibited over-expression of miR-711. |
About TF
| TF name : |
-- |
| TF experiment: |
qRT-PCR,Western blotting,flow cytometry |
| TF experiment description: |
Both knockdown of hypoxia inducible factor 1? (HIF-1?) and inactivation of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF?B) pathway inhibited over-expression of miR-711.;Both knockdown of hypoxia inducible factor 1? (HIF-1?) and inactivation of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF?B) pathway inhibited over-expression of miR-711. |
About Function
| Enhancer function : |
Both knockdown of hypoxia inducible factor 1? (HIF-1?) and inactivation of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF?B) pathway inhibited over-expression of miR-711. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Both knockdown of hypoxia inducible factor 1? (HIF-1?) and inactivation of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF?B) pathway inhibited over-expression of miR-711. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs