About Enhancer
| Enhancer ID: |
E_02_0702 |
| Species: |
mouse |
| Position :
|
chr5:75310474-75312474
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
-- |
| Pubmed ID: |
32278722
|
| Enhancer experiment: |
PCR?Immunostainings |
| Enhancer experiment description: |
We established a con_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_ditional knockout Mouse for the Pdgfra gene (N-PRa-KO) using a Nestin promoter/enhancer driven Cre recombi_x0002_nase and examined forebrain development. The expression of PDGFRa was efficiently suppressed in the Olig2+cells in N-PRa-KO mice. |
About Target gene
| Target gene : |
Pdgfra |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
We established a con_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_ditional knockout Mouse for the Pdgfra gene (N-PRa-KO) using a Nestin promoter/enhancer driven Cre recombi_x0002_nase and examined forebrain development. The expression of PDGFRa was efficiently suppressed in the Olig2+cells in N-PRa-KO mice. |
About TF
| TF name : |
-- |
| TF experiment: |
PCR?Immunostainings |
| TF experiment description: |
We established a con_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_ditional knockout Mouse for the Pdgfra gene (N-PRa-KO) using a Nestin promoter/enhancer driven Cre recombi_x0002_nase and examined forebrain development. The expression of PDGFRa was efficiently suppressed in the Olig2+cells in N-PRa-KO mice. |
About Function
| Enhancer function : |
We established a con_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_ditional knockout Mouse for the Pdgfra gene (N-PRa-KO) using a Nestin promoter/enhancer driven Cre recombi_x0002_nase and examined forebrain development. The expression of PDGFRa was efficiently suppressed in the Olig2+cells in N-PRa-KO mice. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
We established a con_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_ditional knockout Mouse for the Pdgfra gene (N-PRa-KO) using a Nestin promoter/enhancer driven Cre recombi_x0002_nase and examined forebrain development. The expression of PDGFRa was efficiently suppressed in the Olig2+cells in N-PRa-KO mice. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs