About Enhancer

Enhancer ID: E_02_0718
Species: mouse
Position : chr12:85517961-85519961
Biosample name:
Experiment class : High+Lowthroughput
Enhancer type: Enhancer
Disease: --
Pubmed ID:  32667910
Enhancer experiment: RNA-seq,RT-qPCR
Enhancer experiment description: Our findings reveal that 533 genes, including known contractility-driving genes(Gap junction alpha 1 [Gja1], FBJ osteosarcoma oncogene [Fos], Fos-like antigen 2 [Fosl2],Oxytocin receptor [Oxtr], and Prostaglandin G/H synthase 2 (Ptgs2), for example), are up_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_regulated at day 19 during active labor because of an increase in transcription at gene bod_x0002_ies.

About Target gene

Target gene : Fos(D12Rfj1,c-fos,cFos)
Strong evidence: qRT-PCR,qPCR,ChIP,3C
Less strong evidence: RNA-Seq
Target gene experiment description: Our findings reveal that 533 genes, including known contractility-driving genes(Gap junction alpha 1 [Gja1], FBJ osteosarcoma oncogene [Fos], Fos-like antigen 2 [Fosl2],Oxytocin receptor [Oxtr], and Prostaglandin G/H synthase 2 (Ptgs2), for example), are up_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_regulated at day 19 during active labor because of an increase in transcription at gene bod_x0002_ies.

About TF

TF name : --
TF experiment: RNA-seq,RT-qPCR
TF experiment description: Our findings reveal that 533 genes, including known contractility-driving genes(Gap junction alpha 1 [Gja1], FBJ osteosarcoma oncogene [Fos], Fos-like antigen 2 [Fosl2],Oxytocin receptor [Oxtr], and Prostaglandin G/H synthase 2 (Ptgs2), for example), are up_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_regulated at day 19 during active labor because of an increase in transcription at gene bod_x0002_ies.

About Function

Enhancer function : Our findings reveal that 533 genes, including known contractility-driving genes(Gap junction alpha 1 [Gja1], FBJ osteosarcoma oncogene [Fos], Fos-like antigen 2 [Fosl2],Oxytocin receptor [Oxtr], and Prostaglandin G/H synthase 2 (Ptgs2), for example), are up_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_regulated at day 19 during active labor because of an increase in transcription at gene bod_x0002_ies.
Enhancer function experiment: Immunohistochemical staining
Enhancer function
experiment description:
Our findings reveal that 533 genes, including known contractility-driving genes(Gap junction alpha 1 [Gja1], FBJ osteosarcoma oncogene [Fos], Fos-like antigen 2 [Fosl2],Oxytocin receptor [Oxtr], and Prostaglandin G/H synthase 2 (Ptgs2), for example), are up_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_regulated at day 19 during active labor because of an increase in transcription at gene bod_x0002_ies.

About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs