About Enhancer
| Enhancer ID: | E_02_0748 |
| Species: | human |
| Position : | chr14:106327635-106328903   |
| Biosample name: | |
| Experiment class : | Low+High throughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30568279 |
| Enhancer experiment: | Luciferase Reporter Assay,ChIP-seq |
| Enhancer experiment description: | Surprisingly, this enrichment stayed constant thereafter for promoter regions, and increased modestly for enhancer regions, ultimately surpassing the enrichment seen for promoters. In fact, even though promoter chromatin states were more enriched at intermediate HiDRA activity levels,enhancer chromatin states were the most enriched at the highest HiDRA activity levels , suggesting that enhancer elements have a greater dynamic range of regulatory activity potential, which has implications for the regulatory architecture of genes. |
About Target gene
| Target gene : | IGHE(IgE) |
| Strong evidence: | -- |
| Less strong evidence: | Luciferase Reporter Assay |
| Target gene experiment description: | We observed that the peak of HiDRA activity is centered precisely within the region previously identi?ed as driving Enhancer activity in low-throughput luciferase assays (Fig. 2c). |
About TF
| TF name : | -- |
| TF experiment: | -- |
| TF experiment description: | -- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene