About Enhancer
Enhancer ID: |
E_02_0844 |
Species: |
human |
Position :
|
chr7:117011495-117063767 |
Biosample name: |
|
Experiment class :
|
Low+High throughput |
Enhancer type: |
Enhancer |
Disease: |
Cystic fibrosis |
Pubmed ID: |
26615198
|
Enhancer experiment: |
Hi-C,5C,Luciferase Reporter Assay,PCR |
Enhancer experiment description: |
We tested whether any of the newly identiied looping regions displayed enhancer activity in a reporter assay. As shown in Figure 4A, two of our interacting regions significantly enhanced CFTR promoter activity.The fragment encompassing a DHS in the region E displayed a strong Enhancer function with almost 6-fold effect on the CFTR promoter. |
About Target gene
Target gene : |
CFTR(ABC35,ABCC7,CF/MRP,MRP7,TNR-CFTR,dJ760C5.1\) |
Strong evidence: |
-- |
Less strong evidence: |
Luciferase Reporter Assay |
Target gene experiment description: |
As shown in Figure 4A, two of our interacting regions significantly enhanced CFTR promoter activity.The fragment encompassing a DHS in the region E displayed a strong Enhancer function with almost 6-fold effect on the CFTR promoter. |
About TF
TF name : |
-- |
TF experiment: |
-- |
TF experiment description: |
-- |
About Function
Enhancer function : |
-- |
Enhancer function experiment: |
-- |
Enhancer function experiment description: |
-- |
About SNP
Upstream Pathway Annotation of TF
GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs