About Enhancer

Enhancer ID: E_02_0844
Species: human
Position : chr7:117011495-117063767
Biosample name:
Experiment class : Low+High throughput
Enhancer type: Enhancer
Disease: Cystic fibrosis
Pubmed ID:  26615198
Enhancer experiment: Hi-C,5C,Luciferase Reporter Assay,PCR
Enhancer experiment description: We tested whether any of the newly identiied looping regions displayed enhancer activity in a reporter assay. As shown in Figure 4A, two of our interacting regions significantly enhanced CFTR promoter activity.The fragment encompassing a DHS in the region E displayed a strong Enhancer function with almost 6-fold effect on the CFTR promoter.

About Target gene

Target gene : CFTR(ABC35,ABCC7,CF/MRP,MRP7,TNR-CFTR,dJ760C5.1\)
Strong evidence: --
Less strong evidence: Luciferase Reporter Assay
Target gene experiment description: As shown in Figure 4A, two of our interacting regions significantly enhanced CFTR promoter activity.The fragment encompassing a DHS in the region E displayed a strong Enhancer function with almost 6-fold effect on the CFTR promoter.

About TF

TF name : --
TF experiment: --
TF experiment description: --

About Function

Enhancer function : --
Enhancer function experiment: --
Enhancer function
experiment description:
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About SNP

SNP ID: --

Upstream Pathway Annotation of TF

GeneName Pathway Name Source Gene Number

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs