Gene Overview
Target Gene: GRAMD2
NCBI Official Symbol: GRAMD2A
Entrez ID: 196996
Ensembl ID: ENSG00000175318
Gene Full Name: GRAM domain containing 2A
Strand: -
Gene Locus: 15q23
External Links:

GRAMD2 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate GRAMD2   
T(co)Fs that Repress GRAMD2
The Intensity of the Gene Regulated by T(co)Fs:
GRAMD2-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
GRAMD2 TCF3 shRNA Mammary_gland MDA-MB468 0.5655 -0.82241 6.64231e-05 0.00187 DataSet_01_116
GRAMD2 ID1 siRNA Lung A549 0.34326 -1.54261 0.00757 0.13224 DataSet_01_117
GRAMD2 ZIC2 siRNA Pancreas PANC1 2.54476 1.34753 - - DataSet_01_121
GRAMD2 FOXM1 siRNA Central_nervous_system U87 5.30013 2.40603 - - DataSet_01_122
GRAMD2 POLR3A siRNA Mammary_gland MCF7 11.4795 3.52098 - - DataSet_01_139
GRAMD2 HSF1 shRNA Skin A375 1.83117 0.87276 0.10495 0.31011 DataSet_01_155
GRAMD2 ELK1 siRNA Peripheral_blood CD4+ T cells 0 -19.5754 0.50459 0.71276 DataSet_01_162
GRAMD2 GATA3 siRNA Peripheral_blood CD4+ T cells 0 -19.09 0.55223 0.80283 DataSet_01_163
GRAMD2 JUN siRNA Peripheral_blood CD4+ T cells 0 -19.9745 0.45059 0.69415 DataSet_01_164
GRAMD2 MAF siRNA Peripheral_blood CD4+ T cells 0 -19.8937 0.46213 0.78258 DataSet_01_165
GRAMD2 NFATC3 siRNA Peripheral_blood CD4+ T cells 0 -19.712 0.48627 0.75383 DataSet_01_166
GRAMD2 NFKB1 siRNA Peripheral_blood CD4+ T cells 0 -20.0284 0.44214 0.83865 DataSet_01_167
GRAMD2 STAT3 siRNA Peripheral_blood CD4+ T cells 0 -19.7343 0.47933 0.99183 DataSet_01_168
GRAMD2 TP63 shRNA Bladder UC14 1.5509 0.63311 8.88302e-05 0.0014 DataSet_01_183
GRAMD2 GATA2 siRNA Prostate LNCaP 2.70452 1.43537 0.00077 0.00481 DataSet_01_193
GRAMD2 CREB1 shRNA Parotid_gland H3118 MEC 2.49178 1.31718 0.00211 0.11309 DataSet_01_194
GRAMD2 TP63 siRNA Immortalized_keratinocyte HaCaT RG 1.67076 0.7405 - - DataSet_01_197
GRAMD2 TP63 siRNA Head_and_neck SCC-1 1.88468 0.91432 - - DataSet_01_199
GRAMD2 XBP1 shRNA Mammary_gland T47D 0.52462 -0.93065 2.14542e-05 0.00058 DataSet_01_203
GRAMD2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.13044 -2.93858 - - DataSet_01_209
GRAMD2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.30516 -1.71235 - - DataSet_01_210
GRAMD2 EGR3 shRNA Prostate M12 0.52639 -0.92579 0.00094 0.03644 DataSet_01_212
GRAMD2 PTEN shRNA Mammary_gland MCF10A 1.98691 0.99052 2.84525e-05 0.00045 DataSet_01_218
GRAMD2 SNAI2 shRNA Skin Primary human keratinocytes 3.0971 1.63092 2e-04 0.00931 DataSet_01_225
GRAMD2 KLF2 shRNA Bone_marrow RPMI8226 0.30613 -1.70778 0.02053 0.53673 DataSet_01_226
GRAMD2 TWIST1 shRNA Stomach CAF32 2.35781 1.23745 0.25496 0.41122 DataSet_01_253
GRAMD2 TWIST1 shRNA Stomach CAF 1.53862 0.62164 0.30954 0.74659 DataSet_01_254
GRAMD2 SF1 siRNA Endometrial_tissue OsisHESC 1.64323 0.71653 0.00244 0.02839 DataSet_01_271
GRAMD2 SNAI2 siRNA Mammary_gland MCFDCIS 2.44874 1.29204 0.00192 0.37809 DataSet_01_292
GRAMD2 POSTN shRNA Brain GSC272 2.06216 1.04415 0.21506 0.60665 DataSet_01_293
GRAMD2 TFAP4 siRNA Brain BE(2)-C 0.3518 -1.50717 0.49782 0.53121 DataSet_01_295
GRAMD2 PTEN shRNA Skin A431 2.53744 1.34337 0.00055 0.0655 DataSet_01_301
GRAMD2 PTEN shRNA Lung HCC827 0.61907 -0.69181 0.24228 0.69297 DataSet_01_302
GRAMD2 TFAP2C siRNA Lung NCI-H292 0.61486 -0.70166 - - DataSet_01_312
GRAMD2 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 2.40206 1.26427 0.03626 0.30112 DataSet_01_313
GRAMD2 MYC siRNA Colon HCT116 1.58069 0.66055 0.00139 0.00399 DataSet_01_324
GRAMD2 TP63 shRNA Immortalized_keratinocyte HaCaT 0.62289 -0.68295 5.82769e-06 8.51343e-05 DataSet_01_325
GRAMD2 TP63 shRNA Immortalized_keratinocyte HaCaT 0.62289 -0.68295 5.82769e-06 8.51343e-05 DataSet_01_328
GRAMD2 REST siRNA Skin NHEK 1.56091 0.64239 0.00112 0.03605 DataSet_01_337
GRAMD2 GATA3 siRNA Oral_cavity OEC-M1 0.43038 -1.2163 0.01089 0.68576 DataSet_01_347
GRAMD2 HIF1A siRNA Oral_cavity OEC-M1 4.36734 2.12676 4e-04 0.57207 DataSet_01_348
GRAMD2 CDX2 siRNA Colon COLO320 1.62181 0.6976 - - DataSet_01_357
GRAMD2 RBM17 shRNA Liver HepG2 0.05128 -4.2854 0.01633 0.26816 DataSet_02_100
GRAMD2 RBFOX2 shRNA Liver HepG2 0.02564 -5.2854 0.00959 0.65168 DataSet_02_101
GRAMD2 FIP1L1 shRNA Liver HepG2 0.57895 -0.7885 0.48938 0.58784 DataSet_02_103
GRAMD2 TAF15 shRNA Liver HepG2 0.65116 -0.61891 0.9436 0.96454 DataSet_02_106
GRAMD2 SSB shRNA Liver HepG2 0.4375 -1.19265 0.50564 0.57394 DataSet_02_107
GRAMD2 ZNF622 shRNA Liver HepG2 0.5 -1 0.15821 0.22321 DataSet_02_108
GRAMD2 RBM39 shRNA Liver HepG2 0.35897 -1.47805 0.02248 0.21556 DataSet_02_111
GRAMD2 TARDBP shRNA Liver HepG2 0.52381 -0.93289 0.80309 0.85516 DataSet_02_116
GRAMD2 SNRNP70 shRNA Liver HepG2 0.14286 -2.80735 0.13219 0.2311 DataSet_02_126
GRAMD2 SRSF3 shRNA Liver HepG2 0.42857 -1.22239 0.1269 0.26699 DataSet_02_127
GRAMD2 PRPF4 shRNA Liver HepG2 0.54167 -0.88452 0.03453 0.10284 DataSet_02_128
GRAMD2 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 15.5 3.9542 0.18588 0.47399 DataSet_02_129
GRAMD2 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 10.5 3.39232 0.47903 0.58778 DataSet_02_131
GRAMD2 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.8125 0.85798 0.93541 0.96887 DataSet_02_132
GRAMD2 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 16.5 4.04439 0.01987 0.23943 DataSet_02_133
GRAMD2 SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 11 3.45943 0.1086 0.23264 DataSet_02_134
GRAMD2 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 34.5 5.10852 0.01043 0.0964 DataSet_02_135
GRAMD2 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.47616 0.66592 DataSet_02_136
GRAMD2 PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.48805 0.69376 DataSet_02_137
GRAMD2 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.37736 -1.40599 0.61525 0.81861 DataSet_02_139
GRAMD2 RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 14.5 3.85798 0.07042 0.27068 DataSet_02_141
GRAMD2 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.40508 0.58049 DataSet_02_142
GRAMD2 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 4.33333 2.11548 0.06627 0.48869 DataSet_02_146
GRAMD2 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.21739 -2.20163 0.03061 0.12432 DataSet_02_147
GRAMD2 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.20755 -2.26849 0.46984 0.70825 DataSet_02_148
GRAMD2 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.05493 0.23625 DataSet_02_149
GRAMD2 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.24528 -2.02748 0.58518 0.85231 DataSet_02_153
GRAMD2 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 0.13043 -2.9386 0.02927 0.37594 DataSet_02_154
GRAMD2 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.30435 -1.71621 0.19377 0.99879 DataSet_02_157
GRAMD2 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47826 -1.06413 0.03499 0.12158 DataSet_02_158
GRAMD2 SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.56522 -0.82312 0.63162 0.93374 DataSet_02_161
GRAMD2 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 14 3.80735 0.04466 0.13147 DataSet_02_168
GRAMD2 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 1.8 0.848 0.08113 0.15636 DataSet_02_169
GRAMD2 MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.18151 1 DataSet_02_173
GRAMD2 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.75436 1 DataSet_02_177
GRAMD2 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.55556 -0.848 0.23603 1 DataSet_02_178
GRAMD2 ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.10248 1 DataSet_02_180
GRAMD2 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 10 3.32193 0.37037 1 DataSet_02_182
GRAMD2 MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 0.125 -3 0.03266 1 DataSet_02_183
GRAMD2 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.04589 1 DataSet_02_184
GRAMD2 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 4.33333 2.11548 0.13714 1 DataSet_02_190
GRAMD2 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.03571 -4.80735 0.0705 1 DataSet_02_193
GRAMD2 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.125 -3 0.03638 1 DataSet_02_194
GRAMD2 CHD2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.8125 0.85798 0.20378 0.32649 DataSet_02_196
GRAMD2 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.07143 -3.80735 0.14392 1 DataSet_02_199
GRAMD2 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.375 -1.41504 0.11166 1 DataSet_02_202
GRAMD2 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 1.625 0.70044 0.58832 1 DataSet_02_205
GRAMD2 ZFX siRNA Mammary_gland MCF7 2.63158 1.39593 0.05966 0.22388 DataSet_02_206
GRAMD2 TET1 CRISPR Mammary_gland MDA-MB-231 0.583737 -0.776611 2.838481e-02 1.198470e-01 DataSet_03_347
GRAMD2 ZFX siRNA Mammary_gland MCF7 2.23821 1.16234 2.731720e-02 1.164230e-01 DataSet_03_349
GRAMD2 ETV5 knockdown Colon HT29 0.533981 -0.905141 6.505665e-02 0.288611321 DataSet_03_353
GRAMD2 PARP1 siRNA Prostate LNCaP 1.87661 0.908125 4.405393e-01 0.700766903 DataSet_03_354
GRAMD2 CREBBP CRISPR Brain U5-NPC 0.5 -1 0.5726558255 0.7615550 DataSet_03_356
GRAMD2 PTPN14 CRISPR Brain U5-NPC 0.5 -1 5.582034e-01 0.71454579 DataSet_03_357
GRAMD2 NCOA3 siRNA Mammary_gland MDA-MB-231 1.53332 0.616662 3.856408e-01 0.8538322 DataSet_03_361
GRAMD2 ZNF148 shRNA Mammary_gland MDA-MB-231 1.74629 0.804294 4.760541e-02 0.171886994 DataSet_03_366
GRAMD2 USP22 shRNA Liver PLC_PRF_5 cells 2.85714 1.51457 1.355856e-01 0.34549708 DataSet_03_368
GRAMD2 ZNF213 siRNA Mammary_gland MCF7 1.84478 0.883451 3.664564e-01 6.599240e-01 DataSet_03_376
GRAMD2 DNMT1 siRNA Skin Human melanoma cells 3.68024 1.8798 4.035508e-01 5.152756e-01 DataSet_03_382
GRAMD2 NFKBIA shRNA Bone_marrow U2OS 0.00951437 -6.71568 2.720061e-01 0.87005461 DataSet_03_389
GRAMD2 EHF shRNA Stomach MKN7 0.0094318 -6.72825 - - DataSet_03_402
GRAMD2 TFAP2A knockout Embryo H9 0.0251127 -5.31544 3.812666e-05 0.01552045 DataSet_03_405
GRAMD2 CHD1 shRNA Prostate LNCaP 0.634483 -0.656347 2.210180e-02 3.341235e-01 DataSet_03_407
GRAMD2 FOXP3 CRISPR Peripheral_blood Naive Treg 4 2 1.800251e-01 0.538428774 DataSet_03_427
GRAMD2 LHX2 shRNA Bone_marrow ES-derived RPE cells 0.557252 -0.843598 1.700278e-01 1.000000e+00 DataSet_03_428
GRAMD2 CBX2 siRNA Mammary_gland MDA-MB-231 3.31517 1.72908 2.496229e-04 3.493687e-03 DataSet_03_450
GRAMD2 EZH2 siRNA Prostate LNCaP 0.542243 -0.882987 - - DataSet_03_472
GRAMD2 EZH2 siRNA Umbilical_vein HUVEC 0.652174 -0.616671 3.203229e-01 0.589727239 DataSet_03_473
Regulation Region
 
T(co)Fs that significantly regulate NFATC3 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of GRAMD2
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines