Gene Overview
Target Gene: KCNT1
NCBI Official Symbol: KCNT1
Entrez ID: 57582
Ensembl ID: ENSG00000107147
Gene Full Name: potassium sodium-activated channel subfamily T member 1
Strand: +
Gene Locus: 9q34.3
External Links:

KCNT1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate KCNT1   
T(co)Fs that Repress KCNT1
The Intensity of the Gene Regulated by T(co)Fs:
KCNT1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
KCNT1 HOXA1 siRNA Lung_fibroblast IMR-90 1.69003 0.75705 0.457 0.70568 DataSet_01_110
KCNT1 ID1 siRNA Lung A549 1.68928 0.75641 0.53591 0.72184 DataSet_01_117
KCNT1 ELK1 siRNA Peripheral_blood CD4+ T cells 2.14893 1.10362 0.00011 0.00263 DataSet_01_162
KCNT1 GATA3 siRNA Peripheral_blood CD4+ T cells 1.68541 0.7531 0.00378 0.11561 DataSet_01_163
KCNT1 JUN siRNA Peripheral_blood CD4+ T cells 1.62757 0.70272 0.00731 0.05591 DataSet_01_164
KCNT1 NFATC3 siRNA Peripheral_blood CD4+ T cells 439.63 8.78015 0.05624 0.24853 DataSet_01_166
KCNT1 NFKB1 siRNA Peripheral_blood CD4+ T cells 1.51674 0.60097 0.00869 0.26863 DataSet_01_167
KCNT1 HOXB7 siRNA Pancreas MIA PaCa-2 1.5482 0.6306 0.07509 0.62516 DataSet_01_169
KCNT1 TP53 siRNA Lung SAECs 2.21845 1.14955 0.03953 0.37227 DataSet_01_175
KCNT1 CREB1 shRNA Parotid_gland H3118 MEC 3.1728 1.66576 0.35152 0.70113 DataSet_01_194
KCNT1 TP63 siRNA Head_and_neck SCC-6 1.77581 0.82848 - - DataSet_01_202
KCNT1 HIC1 shRNA Mammary_gland HBL100 1.63806 0.71199 - - DataSet_01_205
KCNT1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.66098 -0.59731 - - DataSet_01_208
KCNT1 LIN28A siRNA Embryo H9 0.52958 -0.91708 0.01041 0.0505 DataSet_01_215
KCNT1 IRX1 shRNA Bone_marrow 143B 0.65023 -0.62097 0.46283 0.69012 DataSet_01_227
KCNT1 POSTN shRNA Brain GSC272 3.36057 1.7487 0.02881 0.51529 DataSet_01_293
KCNT1 TFAP4 siRNA Brain BE(2)-C 0.15296 -2.70879 0.28529 0.51625 DataSet_01_295
KCNT1 PTEN shRNA Skin A431 1.90908 0.93288 0.00322 0.0727 DataSet_01_301
KCNT1 GATA3 siRNA Oral_cavity OEC-M1 1.51012 0.59466 0.14183 0.99787 DataSet_01_347
KCNT1 MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.58333 -0.77761 0.16286 1 DataSet_02_173
KCNT1 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.14286 -2.80735 0.02429 1 DataSet_02_174
KCNT1 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.04605 1 DataSet_02_175
KCNT1 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 3.83333 1.9386 0.56851 1 DataSet_02_176
KCNT1 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 1.58333 0.66297 0.09022 1 DataSet_02_177
KCNT1 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.31579 -1.66297 0.10994 1 DataSet_02_178
KCNT1 ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.56088 1 DataSet_02_181
KCNT1 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.58333 -0.77761 0.0406 1 DataSet_02_184
KCNT1 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 1.71429 0.77761 0.66313 1 DataSet_02_185
KCNT1 BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.05074 1 DataSet_02_186
KCNT1 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.5054 1 DataSet_02_189
KCNT1 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 2.63636 1.39855 0.31915 1 DataSet_02_191
KCNT1 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.29142 1 DataSet_02_192
KCNT1 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.09091 1.06413 0.0597 1 DataSet_02_194
KCNT1 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.42672 1 DataSet_02_195
KCNT1 CHD2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.75 0.80735 0.1982 0.32081 DataSet_02_196
KCNT1 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 2 1 1 1 DataSet_02_197
KCNT1 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 1 1 DataSet_02_202
KCNT1 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 0.31579 -1.66297 0.109 1 DataSet_02_203
KCNT1 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 4.16667 2.05889 0.17289 1 DataSet_02_205
KCNT1 ASCL1 siRNA Lung DMS79 0.629291 -0.668202 0.101334726523141 0.767005768213426 DataSet_03_016
KCNT1 ATF4 siRNA Skin A375 0.659643 -0.600241 0.213927494953367 0.775512819201899 DataSet_03_018
KCNT1 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.531248 -0.912543 0.244537913903066 0.835808552701308 DataSet_03_025
KCNT1 GATA4 siRNA Stomach AGS 1.9519 0.964876 0.172114257254316 0.817533283799563 DataSet_03_105
KCNT1 GATA6 siRNA Stomach AGS 1.84949 0.887124 0.1557227348761 0.656056287187411 DataSet_03_108
KCNT1 GATA6 siRNA Stomach YCC3 1.50506 0.589819 0.21992893343732 0.814033790684719 DataSet_03_110
KCNT1 KLF5 siRNA Stomach AGS 1.55394 0.635935 0.275790395567217 0.732790308712648 DataSet_03_149
KCNT1 KLF5 siRNA Stomach KatoIII 0.641881 -0.639623 0.175891493990566 0.625806020872147 DataSet_03_150
KCNT1 KLF5 siRNA Stomach YCC3 1.52463 0.608459 0.237575631776102 0.605116479194483 DataSet_03_151
KCNT1 MEF2D siRNA Liver HuH7 0.417561 -1.25994 - - DataSet_03_163
KCNT1 MYC siRNA Colon HT29 2.37894 1.25032 - - DataSet_03_177
KCNT1 PHB shRNA Embryo Embryonic stem cells (ESCs) 1.64061 0.714232 0.152721122571777 0.269422794426619 DataSet_03_211
KCNT1 REST siRNA Adrenal_gland H295R/TR 1.64734 0.720142 0.0435840103960369 0.382946860572629 DataSet_03_228
KCNT1 SOX11 siRNA Lung_fibroblast NHLF 1.79428 0.843403 0.0124752537103651 0.208250452787578 DataSet_03_238
KCNT1 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 1.68421 0.752072 - - DataSet_03_246
KCNT1 STAT3 CRISPR Embryo hESC 7.05423 2.81849 0.00178992769482291 0.0310548613630627 DataSet_03_258
KCNT1 STAT6 siRNA Umbilical_vein HUVEC 0.483235 -1.0492 0.175908518500175 0.837635960915423 DataSet_03_264
KCNT1 TFAP2C siRNA Mammary_gland MCF7 2.21668 1.1484 0.072698126653092 0.411842311578222 DataSet_03_274
KCNT1 TFE3 siRNA Kidney UOK257-2 0.487401 -1.03682 - - DataSet_03_275
KCNT1 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 248 7.9542 5.07605745280753e-05 0.00260888698448343 DataSet_04_014
KCNT1 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.419355 -1.25376 0.0297086734336284 0.482324531218369 DataSet_04_022
KCNT1 CNOT7 CRISPR Liver HepG2 2 1 0.700430746820031 0.824013322732581 DataSet_04_045
KCNT1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.44444 1.78427 0.351244692324268 0.608976919230298 DataSet_02_38
KCNT1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.419355 -1.25376 0.102210451198804 0.489495240580444 DataSet_02_75
KCNT1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 6.59259 2.72085 0.00746653347067308 0.408966926633667 DataSet_02_45
KCNT1 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.66667 0.736966 0.371041703600419 0.554387155159659 DataSet_02_35
KCNT1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.48148 1.7997 0.268279795418329 0.533325401293353 DataSet_02_32
KCNT1 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.405405 -1.30256 0.293781205242438 0.699753365614809 DataSet_02_49
KCNT1 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.518519 -0.947533 0.243240040150191 0.40788723441742 DataSet_02_53
KCNT1 CNOT3 shRNA Lung A549 1.61443 0.691024 1.504875e-01 0.8830540 DataSet_03_340
KCNT1 ELF3 CRISPR Bile_duct HBDEC2 0.640442 -0.642859 4.910891e-03 2.028005e-02 DataSet_03_304
KCNT1 SNAI2 shRNA Pancreas KLM1 1.73232 0.792701 8.856328e-02 0.39128779 DataSet_03_307
KCNT1 BRCA1 siRNA Mammary_gland MCF7 1.63637 0.7105 9.830724e-02 0.9999931 DataSet_03_308
KCNT1 TET1 CRISPR Mammary_gland MDA-MB-231 20.3206 4.34487 5.778511e-01 7.405950e-01 DataSet_03_347
KCNT1 TET1 CRISPR Mammary_gland Hs578T 0.361082 -1.4696 8.017419e-01 8.968887e-01 DataSet_03_355
KCNT1 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 0.0371301 -4.75127 4.956313e-02 2.425727e-01 DataSet_03_359
KCNT1 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 1.71047 0.774389 6.212115e-01 7.041552e-01 DataSet_03_362
KCNT1 MYC siRNA Peripheral_blood T lymphocyte 1.5922 0.671025 5.448481e-01 0.759918907 DataSet_03_363
KCNT1 TP53 knockout Stomach SNU1 0.342006 -1.54791 0.0334857429 0.9301241 DataSet_03_365
KCNT1 DNMT3A knockout Embryo_kidney HEK293T 0.529531 -0.917212 - - DataSet_03_369
KCNT1 ZFP36L1 siRNA Urinary_bladder J82 3.5 1.80735 - - DataSet_03_371
KCNT1 EZH2 CRISPR Ovary SKOV3 2.5 1.32193 2.937428e-02 0.1415536441 DataSet_03_378
KCNT1 ZBTB7A siRNA Stomach BGC823 0.21663 -2.20669 - - DataSet_03_380
KCNT1 TCF19 CRISPR Oral_squamous CAL27 3.15682 1.65847 2.068795e-02 0.1209629954 DataSet_03_383
KCNT1 YY1 shRNA Brain GSC1517 0.0769231 -3.70044 - - DataSet_03_384
KCNT1 YY1 shRNA Brain GSC23 3.5 1.80736 - - DataSet_03_385
KCNT1 YY1 shRNA Brain GSC3028 5 2.32193 - - DataSet_03_386
KCNT1 TRIM8 siRNA Mammary_gland MCF7 2.6 1.37851 3.678164e-01 0.5721548344 DataSet_03_388
KCNT1 NFKBIA shRNA Bone_marrow U2OS 0.0362992 -4.78392 6.882644e-01 0.87696698 DataSet_03_389
KCNT1 KDM5A CRISPR Lung GLC16 0.299861 -1.73763 2.727615e-02 0.080198055 DataSet_03_392
KCNT1 ILF2 siRNA Stomach SGC-7901 0.25 -2 0.0599040506 0.17949356 DataSet_03_393
KCNT1 BMI1 shRNA Bile_duct QBC-939 0.337258 -1.56807 7.581976e-01 0.8724802786 DataSet_03_395
KCNT1 IKZF2 CRISPR Lymph CAR T Cell 10.308 3.36569 3.758908e-01 0.781165820 DataSet_03_397
KCNT1 TLE4 CRISPR Lymph CAR T Cell 0.411252 -1.28191 9.057841e-01 0.98482206 DataSet_03_398
KCNT1 RELA CRISPR Brain T30 0.000453238 -11.1074 0.3259418932 0.8400824 DataSet_03_399
KCNT1 EHF shRNA Stomach MKN7 26.0093 4.70096 - - DataSet_03_402
KCNT1 CDK7 shRNA Bone_marrow D458 2.33333 1.22239 7.243555e-01 0.86638865 DataSet_03_404
KCNT1 TFAP2A knockout Embryo H9 2 1 7.561071e-01 0.82701905 DataSet_03_405
KCNT1 SATB2 CRISPR Colon Colon organoid 1.83333 0.874469 3.181762e-01 0.95735254 DataSet_03_406
KCNT1 STRAP knockout Nerve SK-N-AS 14.3758 3.84558 - - DataSet_03_409
KCNT1 ZKSCAN3 CRISPR Colon HCT116 0.311828 -1.68118 1.215857e-01 0.518553205 DataSet_03_415
KCNT1 FOXK2 shRNA Ovary OVCAR-5 0.428571 -1.22239 7.174716e-02 0.22469284 DataSet_03_419
KCNT1 STAT5B CRISPR Embryo_kidney HEK293 2.66667 1.41504 1.280387e-01 0.657354120 DataSet_03_424
KCNT1 NFE2L1 knockout Lung A549 1.98804 0.991349 7.833338e-01 9.984904e-01 DataSet_03_433
KCNT1 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 8 3 2.504852e-01 0.574894029 DataSet_03_434
KCNT1 SUFU shRNA Mammary_gland HCC1954 cells 0.5 -1 0.7512259100 0.9077059 DataSet_03_437
KCNT1 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.333333 -1.58496 3.827322e-01 0.90558273 DataSet_03_439
KCNT1 SETDB1 shRNA Colon HCT116 0.511908 -0.966045 - - DataSet_03_440
KCNT1 CAMTA1 knockout Embryo_kidney HEK293T 2.14286 1.09954 1.215617e-02 0.11693143 DataSet_03_448
KCNT1 RELB CRISPR Colon SW480 2.36842 1.24393 7.767692e-02 2.544543e-01 DataSet_03_449
KCNT1 CBX2 siRNA Mammary_gland MDA-MB-231 3.09089 1.62802 4.305013e-01 6.481864e-01 DataSet_03_450
KCNT1 ZFP36L1 CRISPR Lung NCI-H1876 0.439064 -1.1875 3.337517e-02 0.756872327 DataSet_03_454
KCNT1 PPARG siRNA Aortic_valve Valvular endothelial cell 0.333333 -1.58496 2.202948e-02 2.152169e-01 DataSet_03_456
KCNT1 ARID1A shRNA Bile_duct MMNK1 1.55223 0.634341 9.021264e-01 0.972301787 DataSet_03_458
KCNT1 PARP1 knockout Embryo_kidney HEK293a 1.58333 0.662965 8.451009e-03 2.758992e-02 DataSet_03_464
KCNT1 LIN28A siRNA Mammary_gland MCF7M 0.660134 -0.599168 8.352113e-01 0.9811006 DataSet_03_469
KCNT1 LIN28A siRNA Mammary_gland MCF7M 0.660134 -0.599168 8.352113e-01 0.9811006 DataSet_03_470
KCNT1 EZH2 siRNA Prostate LNCaP 0.602409 -0.731185 - - DataSet_03_472
Regulation Region
 
T(co)Fs that significantly regulate YY1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of KCNT1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines