Gene Overview
| Target Gene: | Marco |
| NCBI Official Symbol: | Marco |
| Entrez ID: | 17167 |
| Ensembl ID: | ENSMUSG00000026390 |
| Gene Full Name: | macrophage receptor with collagenous structure |
| Strand: | - |
| Gene Locus: | 1|1 E2.3 |
| External Links: |
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Marco Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Marco
T(co)Fs
that Repress Marco
The Intensity of the Gene Regulated by T(co)Fs:
Marco-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Marco | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.526549 | -0.925361 | 0.23508239953178 | 0.606956845527733 | DataSet_11_014 |
| Marco | Cebpb | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.169831 | -2.55783 | - | - | DataSet_11_021 |
| Marco | Cebpe | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.0671341 | -3.89681 | - | - | DataSet_11_023 |
| Marco | Dmrt1 | knockout | Testis | Juvenile testes | 1.98935 | 0.992296 | 0.273096638776498 | 0.781319786250083 | DataSet_11_025 |
| Marco | Dmrt1 | knockout | Testis | Juvenile testes | 2.49635 | 1.31982 | 0.16276422098009 | 0.932139260123802 | DataSet_11_026 |
| Marco | Dmrt1 | knockout | Testis | Juvenile testes | 1.50262 | 0.587481 | 0.0674744513283869 | 0.820677870410133 | DataSet_11_027 |
| Marco | Dmrt1 | knockout | Testis | Juvenile testes | 2.56083 | 1.35661 | 0.045797823919937 | 0.830739734023206 | DataSet_11_028 |
| Marco | E2f4 | knockout | Brain | Forebrain | 0.426434 | -1.2296 | - | - | DataSet_11_034 |
| Marco | Elf5 | knockout | Mammary_gland | Mammary gland | 5.30485 | 2.40731 | 0.00419066238714903 | 0.184241472964188 | DataSet_11_035 |
| Marco | Foxp1 | knockout | Eye | Lens | 0.415441 | -1.26728 | - | - | DataSet_11_044 |
| Marco | Gata3 | siRNA | Peripheral_blood | CD4+ T helper (Th) cells | 1.51374 | 0.598115 | 0.186250821486703 | 0.987135756219234 | DataSet_11_048 |
| Marco | Gfi1 | knockout | Cord_Blood | T-cells | 0.590909 | -0.758992 | 0.308249117627573 | 0.691026533951482 | DataSet_11_053 |
| Marco | Junb | shRNA | Tibialis_anterior_muscle | Tibialis anterior muscle | 0.272257 | -1.87696 | 0.00855309153403779 | 0.107343910621671 | DataSet_11_065 |
| Marco | Lhx8 | knockout | Ovary | Ovary | 0.248488 | -2.00875 | 0.0415518193927077 | 0.123294175396874 | DataSet_11_070 |
| Marco | Lmx1b | knockout | Kidney | Kidney | 0.586584 | -0.76959 | 0.177495854683275 | 0.574925862388877 | DataSet_11_072 |
| Marco | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 1.9 | 0.925999 | - | - | DataSet_11_074 |
| Marco | Neurod1 | knockout | Eye | Pineal gland | 0.496882 | -1.00903 | 0.0371903525282393 | 0.315626016141501 | DataSet_11_087 |
| Marco | Neurod1 | knockout | Eye | Pineal gland | 0.620365 | -0.68881 | 0.770049430787032 | 0.999269041168372 | DataSet_11_089 |
| Marco | Nhlh2 | knockout | Eye | Retina | 0.608696 | -0.716207 | 0.455747283670028 | 0.598463914163373 | DataSet_11_092 |
| Marco | Nr2f2 | knockout | Ovary | E14.5 Ovary | 2.23742 | 1.16183 | 0.076374300848354 | 0.834975080343504 | DataSet_11_094 |
| Marco | Nrf1 | knockdown | Liver | Liver | 10.106 | 3.33713 | 0.0301524410702066 | 0.0844283979065732 | DataSet_11_096 |
| Marco | Plagl2 | knockout | Intestine | Small intestine | 0.589744 | -0.76184 | 0.201336604012028 | 0.509142092147341 | DataSet_11_104 |
| Marco | Prox1 | knockout | Liver | Liver | 2.77173 | 1.47079 | - | - | DataSet_11_109 |
| Marco | Runx1 | knockout | Mammary_gland | Luminal epithelial cells | 1.61975 | 0.695771 | 0.18687457919759 | 0.999784944667092 | DataSet_11_117 |
| Marco | Smad4 | knockout | Aorta | Aortic arteries | 18.9754 | 4.24606 | 0.321732331848247 | 0.729520926231896 | DataSet_11_128 |
| Marco | Sp3 | knockout | Heart | Heart | 0.307371 | -1.70195 | 0.045612882978224 | 0.692225500100343 | DataSet_11_145 |
| Marco | Spdef | knockout | Colon | Colon | 0.191394 | -2.38538 | 0.144670107481591 | 0.997507742354799 | DataSet_11_146 |
| Marco | Spdef | knockout | Stomach | Stomach | 0.296869 | -1.7521 | 0.496888285954744 | 0.927008425161439 | DataSet_11_147 |
| Marco | Stat3 | knockout | Lung | Lung typeII cells | 1.90286 | 0.928166 | 0.00674572965636029 | 0.536336682740396 | DataSet_11_151 |
| Marco | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 0.660256 | -0.598903 | 0.117833830953298 | 0.891113978028878 | DataSet_11_152 |
| Marco | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 1.64025 | 0.713918 | 0.16062610711889 | 0.343777328217202 | DataSet_11_153 |
| Marco | Tbx1 | knockout | Ear | Otic vesicles | 2.09513 | 1.06704 | 0.446293272314112 | 0.996209135879357 | DataSet_11_154 |
| Marco | Tsc22d4 | shRNA | Liver | Liver | 0.649884 | -0.621745 | 0.0328997810827009 | 0.0915203182194441 | DataSet_11_169 |
| Marco | Yy1 | knockout | White_adipose_tissue | Subcutaneous white adipose tissue | 0.544678 | -0.876523 | 0.684735653700192 | 0.914923085367501 | DataSet_11_184 |
| Marco | Yy1 | knockout | White_adipose_tissue | Visceral white adipose tissue | 3.10182 | 1.63311 | 0.00397781503427851 | 0.041006260170383 | DataSet_11_185 |
| Marco | Pogz | knockdown | Liver | fetal liver | 1.52623 | 0.609973 | 1.238719e-01 | 0.4307237 | DataSet_11_188 |
| Marco | Cpeb1 | siRNA | Neuron | Neuro-2a | 2.06542 | 1.04643 | - | - | DataSet_11_189 |
| Marco | Kdm5b | knockout | Heart | left ventricles | 1.98146 | 0.986561 | 0.4031769452 | 0.9999827 | DataSet_11_210 |
| Marco | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 2.50667 | 1.32577 | 7.104380e-02 | 1.966439e-01 | DataSet_11_192 |
| Marco | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 2.88571 | 1.52893 | - | - | DataSet_11_196 |
| Marco | Prdm11 | knockout | Lung | Lung | 1.5189 | 0.603025 | 2.686509e-03 | 0.085770328 | DataSet_11_198 |
| Marco | Dnmt1 | knockout | Liver | Liver | 2.19074 | 1.13142 | 2.972289e-04 | 1.384521e-02 | DataSet_11_232 |
| Marco | Dnmt3a | siRNA | Peritoneum | peritoneal macrophages | 0.644228 | -0.634357 | - | - | DataSet_11_222 |
| Marco | Ncl | siRNA | Embryo | ES cells | 0.5 | -1 | 5.387640e-01 | 0.7602370600 | DataSet_11_240 |
| Marco | Dnmt3a | siRNA | Embryo | iPSC | 67.57 | 6.07831 | - | - | DataSet_11_241 |
| Marco | Lin28a | knockout | Heart | Heart | 0.136345 | -2.87466 | 0.2612732071 | 0.8777652 | DataSet_11_243 |
| Marco | Tet1 | shRNA | Muscle | MLL-ENL-ERtm | 2.55817 | 1.35511 | 3.031610e-02 | 6.111932e-02 | DataSet_11_249 |
| Marco | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.428571 | -1.22239 | 8.785292e-01 | 9.265043e-01 | DataSet_11_250 |
| Marco | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 2.37092 | 1.24545 | 7.519314e-01 | 0.862590960 | DataSet_11_252 |
| Marco | Eed | knockout | Brain | Forebrain | 0.562849 | -0.829179 | 9.604258e-01 | 9.946579e-01 | DataSet_11_258 |
| Marco | Eed | knockout | Spinal_cord | spinal cord | 0.563157 | -0.828391 | 7.384091e-01 | 9.999790e-01 | DataSet_11_261 |
| Marco | Fubp1 | shRNA | Bone_marrow | BM cells | 4.5 | 2.16992 | 2.257122e-04 | 0.069358999 | DataSet_11_262 |
| Marco | Ctnnb1 | knockout | Embryo | MGE cells | 0.191389 | -2.38542 | 6.250923e-02 | 0.271460896 | DataSet_11_266 |
| Marco | Mef2d | CRISPR | Heart | Cardiac ventricle | 2.33912 | 1.22597 | 6.172315e-01 | 0.7969997585 | DataSet_11_270 |
| Marco | Lin28b | knockout | Bone_marrow | Bone marrow immature B cells | 3.33333 | 1.73697 | 3.628919e-01 | 0.9643594 | DataSet_11_274 |
| Marco | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 1.55556 | 0.63743 | - | - | DataSet_11_285 |
| Marco | Pdx1 | CRISPR | Liver | Liver | 0.515028 | -0.957277 | 4.344600e-01 | 0.596024894 | DataSet_11_286 |
| Marco | Mkl1 | knockout | Bone_marrow | Bone marrow differentiated macrophages | 2.04445 | 1.03171 | 2.475693e-01 | 0.6162668943 | DataSet_11_294 |
| Marco | Hmg20a | siRNA | Hypothalamus | Primary hypothalamic astrocytes | 10 | 3.32193 | 0.0145194812 | 0.2501520 | DataSet_11_300 |
| Marco | Arid2 | knockout | Muscle | LSK | 63.0909 | 5.97936 | 4.322443e-27 | 8.631487e-23 | DataSet_11_301 |
| Marco | Cited2 | knockout | Haematopoietic_and_lymphoid_tissue | Hematopoietic stem cell (HSC) | 4.16667 | 2.05889 | - | - | DataSet_11_308 |
| Marco | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 0.0699035 | -3.83849 | 4.074554e-01 | 0.80359421 | DataSet_11_310 |
| Marco | Suz12 | knockout | Lung | Alveolar macrophage | 4.97998 | 2.31614 | 4.111712e-03 | 0.0953292766 | DataSet_11_311 |
| Marco | Suz12 | knockout | Lung | Alveolar macrophage | 2.64803 | 1.40492 | 5.667318e-03 | 5.275016e-02 | DataSet_11_312 |
| Marco | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 0.0737705 | -3.76081 | - | - | DataSet_11_313 |
| Marco | Ahr | knockout | Liver | Liver | 1.74923 | 0.80672 | 6.208509e-01 | 0.8484638063 | DataSet_11_315 |
| Marco | Satb2 | knockout | Colon | Intestine epithelium | 0.0857143 | -3.54432 | 1.565771e-03 | 0.0703533597 | DataSet_11_316 |
| Marco | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 10.5 | 3.39232 | 9.190456e-03 | 0.1184907785 | DataSet_11_317 |
| Marco | Arid2 | knockout | Bone_marrow | bone marrow leukemia cells | 4.4 | 2.1375 | 1.163644e-01 | 0.7021662 | DataSet_11_318 |
| Marco | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.320611 | -1.64111 | 4.162667e-02 | 3.727509e-01 | DataSet_11_319 |
| Marco | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.516729 | -0.952521 | 4.718456e-01 | 6.661530e-01 | DataSet_11_320 |
| Marco | Bud31 | knockout | Testis | Spermatogonial stem cells | 2 | 1 | 6.274740e-01 | 0.8746401 | DataSet_11_321 |
| Marco | Prmt1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.6 | -0.736966 | 6.013705e-01 | 0.9832045 | DataSet_11_325 |
| Marco | Tet1 | siRNA | Embryo | Embryonic fibroblasts | 1.98684 | 0.990477 | 5.921504e-01 | 0.9609895 | DataSet_11_327 |
| Marco | Dnmt3l | knockout | Testis | Spermatogonial progenitor cells | 1.97143 | 0.979243 | - | - | DataSet_11_328 |
| Marco | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 2 | 1 | 5.871495e-01 | 8.207834e-01 | DataSet_11_332 |
| Marco | Dnmt3a | siRNA | Heart | embryonic cardiomyocytes | 0.454545 | -1.1375 | 2.580165e-01 | 0.69832724 | DataSet_11_337 |
| Marco | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 5.45455 | 2.44746 | 1.508323e-02 | 0.38745156 | DataSet_11_338 |
| Marco | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.181818 | -2.45943 | 5.471006e-02 | 0.112429184 | DataSet_11_340 |
Regulation Region
Expression Atlas of Marco