Gene Overview
Target Gene: NAT8B
NCBI Official Symbol: NAT8B
Entrez ID: 51471
Ensembl ID: ENSG00000204872
Gene Full Name: N-acetyltransferase 8B (putative, gene/pseudogene)
Strand: -
Gene Locus: 2p13.1
External Links:

NAT8B Significantly Regulated by These T(co)Fs

T(co)Fs that Activate NAT8B   
T(co)Fs that Repress NAT8B
The Intensity of the Gene Regulated by T(co)Fs:
NAT8B-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
NAT8B AR siRNA Prostate abl cells 1.52941 0.612977 0.55961192938139 0.999852161656754 DataSet_03_004
NAT8B AR siRNA Prostate LNCaP 0.261194 -1.93681 0.0530918261296206 1 DataSet_03_005
NAT8B ATF4 siRNA Skin A375 0.62832 -0.670428 0.165221503112717 0.775512819201899 DataSet_03_018
NAT8B BCL6 siRNA Lymph Pfeiffer DLBCL 1.59629 0.674727 0.532125665999537 0.854860942458915 DataSet_03_026
NAT8B GATA2 siRNA Uterus Decidual stromal cells 3.40148 1.76616 0.00655119407677268 0.361903336052328 DataSet_03_100
NAT8B GATA4 siRNA Stomach KatoIII 0.490094 -1.02887 0.129126065940655 0.901745195691908 DataSet_03_106
NAT8B GATA4 siRNA Stomach YCC3 0.413116 -1.27538 0.226740334310586 0.74955837950513 DataSet_03_107
NAT8B GATA6 siRNA Stomach YCC3 0.491566 -1.02454 0.148793142340252 0.762734747231135 DataSet_03_110
NAT8B HNF4a siRNA Liver HepG2 0.345529 -1.53312 0.00947933943557468 0.488750227327071 DataSet_03_126
NAT8B KLF5 siRNA Stomach AGS 1.56614 0.647214 0.370580230944594 0.782653054257089 DataSet_03_149
NAT8B KLF5 siRNA Stomach KatoIII 0.48847 -1.03366 0.224698435744825 0.672135648456465 DataSet_03_150
NAT8B MEF2D shRNA Liver HuH7 0.547863 -0.868113 - - DataSet_03_162
NAT8B MITF siRNA Skin Ma-Mel-15 0.66621 -0.585951 0.154181287058536 0.608390010805494 DataSet_03_166
NAT8B MITF siRNA Skin Ma-Mel-15 0.623413 -0.68174 0.00979611025793687 0.135212049505292 DataSet_03_167
NAT8B MITF siRNA Skin SK-MEL-5 0.57486 -0.798718 0.000558658393815043 0.00212940988659325 DataSet_03_168
NAT8B MYB siRNA Cord_Blood CD34+ progenitor cells 10.3817 3.37597 - - DataSet_03_170
NAT8B MYC siRNA Colon HT29 0.15093 -2.72804 - - DataSet_03_177
NAT8B PHB shRNA Embryo Embryonic stem cells (ESCs) 0.5285 -0.920025 0.317775601914271 0.465433253936661 DataSet_03_211
NAT8B SOX11 siRNA Lung_fibroblast NHLF 0.371675 -1.42789 0.062215043972873 0.418155840896771 DataSet_03_237
NAT8B SOX11 siRNA Lung_fibroblast NHLF 0.325927 -1.61738 0.0521014158676494 0.333655912023507 DataSet_03_238
NAT8B SOX2 CRISPR Seminoma-like TCam-2 1.79526 0.844193 0.271475836832445 0.999580851453413 DataSet_03_244
NAT8B SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 8.4 3.07039 - - DataSet_03_246
NAT8B STAT3 CRISPR Embryo hESC 0.44499 -1.16815 0.299212759339562 0.374170749981193 DataSet_03_258
NAT8B STAT6 siRNA Umbilical_vein HUVEC 0.234848 -2.0902 0.250753964544656 0.864148112296434 DataSet_03_264
NAT8B TFAP2C siRNA Mammary_gland MCF7 2.62108 1.39016 0.225411687109943 0.572652520455867 DataSet_03_274
NAT8B TFE3 siRNA Kidney UOK257-2 2.73016 1.44898 - - DataSet_03_275
NAT8B APTX CRISPR Liver HepG2 2 1 0.773288057175258 0.993351530715001 DataSet_04_069
NAT8B SEPT11 CRISPR Liver HepG2 0.458333 -1.12553 0.321778650807186 0.584775140483071 DataSet_04_068
NAT8B SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.57143 0.652077 0.78776287671089 1 DataSet_04_077
NAT8B SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.57143 1.36257 0.387182761206454 0.741737580181896 DataSet_04_073
NAT8B HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.14286 2.05063 0.439612641636282 0.773921284697302 DataSet_02_75
NAT8B UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.717730826725766 0.879618370631228 DataSet_04_062
NAT8B CNOT3 shRNA Lung A549 1.63242 0.707008 5.489730e-01 0.9339408 DataSet_03_340
NAT8B NFKBIZ knockout Colon Colon organoid 0.560426 -0.835403 1.598925e-01 0.668541256 DataSet_03_323
NAT8B SNAI2 shRNA Pancreas pancreatic cancer stem cells 0.602999 -0.729773 1.216049e-01 0.6510154 DataSet_03_306
NAT8B INO80 siRNA Muscle RD 0.414527 -1.27046 - - DataSet_03_344
NAT8B BRCA1 siRNA Mammary_gland MCF7 0.480093 -1.05861 1.481382e-01 0.9999931 DataSet_03_308
NAT8B ESR1 siRNA Mammary_gland MCF7 0.236284 -2.0814 8.693078e-03 0.0629907253 DataSet_03_352
NAT8B SMARCA2 shRNA Lung NCI-H1944 2 1 5.456354e-01 7.902236e-01 DataSet_03_377
NAT8B ILF2 siRNA Stomach SGC-7901 0.25 -2 0.3132694608 0.50566494 DataSet_03_393
NAT8B SATB2 CRISPR Colon Colon organoid 1.64286 0.716207 4.524589e-01 0.96870441 DataSet_03_406
NAT8B E2F1 siRNA Prostate LNCaP 5 2.32193 1.680504e-01 0.7152214543 DataSet_03_413
NAT8B MAEL CRISPR Liver Alexander cells 17 4.08746 - - DataSet_03_423
NAT8B USP7 shRNA Skin xenograft cells 0.461538 -1.11548 0.06545492 0.4348960 DataSet_03_431
NAT8B PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.380952 -1.39232 - - DataSet_03_432
NAT8B FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 4.30769 2.10692 7.309444e-02 0.90558273 DataSet_03_439
NAT8B CBX2 siRNA Mammary_gland MCF7 0.224409 -2.1558 4.296665e-02 0.0959335361 DataSet_03_451
NAT8B OGT siRNA Embryo BeWo cells 22 4.45943 3.694896e-04 0.13877926 DataSet_03_453
NAT8B PPARG siRNA Aortic_valve Valvular endothelial cell 2.04545 1.03242 1.511867e-01 5.789082e-01 DataSet_03_456
NAT8B IRF2 shRNA Cord_Blood CD34+ cells 1.92105 0.941897 - - DataSet_03_460
NAT8B TXNIP shRNA Cord_Blood CD34+ cells 0.6 -0.736966 - - DataSet_03_461
NAT8B SOX9 knockout Liver HuH7 14 3.80735 8.624206e-05 1.908794e-03 DataSet_03_463
NAT8B EZH2 siRNA Umbilical_vein HUVEC 0.5 -1 2.240764e-01 0.495154344 DataSet_03_473
Regulation Region
 
T(co)Fs that significantly regulate OGT by the evidences of both expression and ChIP-seq/motif
Expression Atlas of NAT8B
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines