Gene Overview
Target Gene: PABPC4L
NCBI Official Symbol: PABPC4L
Entrez ID: 132430
Ensembl ID: ENSG00000254535
Gene Full Name: poly(A) binding protein cytoplasmic 4 like
Strand: -
Gene Locus: 4q28.3
External Links:

PABPC4L Significantly Regulated by These T(co)Fs

T(co)Fs that Activate PABPC4L   
T(co)Fs that Repress PABPC4L
The Intensity of the Gene Regulated by T(co)Fs:
PABPC4L-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
PABPC4L IRF2 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 2.58589 1.37066 0.05902 0.323 DataSet_01_100
PABPC4L IRF6 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 2.81525 1.49326 0.05775 0.20852 DataSet_01_101
PABPC4L MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 7.22185 2.85237 4.51191e-11 7.56606e-09 DataSet_01_102
PABPC4L ARID1A shRNA Ovary OSE4 0.66485 -0.5889 - - DataSet_01_108
PABPC4L ARID1A shRNA Ovary IOSE80pc 0.54943 -0.864 - - DataSet_01_109
PABPC4L HOXA1 siRNA Lung_fibroblast IMR-90 0.60758 -0.71886 0.04163 0.21854 DataSet_01_110
PABPC4L ESR1 siRNA Mammary_gland MCF7 0.65176 -0.61758 0.00022 0.01969 DataSet_01_111
PABPC4L ID1 siRNA Lung H1650 3.69707 1.88638 0.13247 0.4842 DataSet_01_118
PABPC4L ZIC2 siRNA Pancreas PANC1 1.68766 0.75503 - - DataSet_01_121
PABPC4L FOXM1 siRNA Central_nervous_system U87 0.02993 -5.06224 - - DataSet_01_122
PABPC4L EGR4 siRNA Lung SBC-5 1.79137 0.84107 0.03621 0.29188 DataSet_01_132
PABPC4L POLR3A siRNA Mammary_gland MCF7 0.54278 -0.88157 - - DataSet_01_139
PABPC4L HSF1 shRNA Skin A375 0.61489 -0.7016 0.00035 0.00575 DataSet_01_155
PABPC4L GATA2 siRNA Prostate LNCaP 0.41489 -1.26919 0.17919 0.29776 DataSet_01_193
PABPC4L CREB1 shRNA Parotid_gland H3118 MEC 1.73671 0.79636 0.8595 0.94981 DataSet_01_194
PABPC4L TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.103 -3.2793 - - DataSet_01_197
PABPC4L TP63 siRNA Head_and_neck SCC-1 0.16914 -2.56369 - - DataSet_01_199
PABPC4L TP63 siRNA Immortalized_keratinocyte HaCaT 0.63992 -0.64405 - - DataSet_01_200
PABPC4L TP63 siRNA Head_and_neck SCC-6 0.19788 -2.33728 - - DataSet_01_202
PABPC4L FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 7.89391 2.98074 - - DataSet_01_208
PABPC4L FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 7.34684 2.87712 - - DataSet_01_209
PABPC4L FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 2.84273 1.50728 - - DataSet_01_210
PABPC4L REST siRNA Prostate LNCaP 2.21955 1.15027 0.00207 0.10556 DataSet_01_211
PABPC4L KLF2 shRNA Bone_marrow RPMI8226 0.11842 -3.07801 0.00235 0.415 DataSet_01_226
PABPC4L YBX1 shRNA Mammary_gland MDA 2.10095 1.07104 1.39337e-09 1.64985e-07 DataSet_01_255
PABPC4L YBX1 shRNA Mammary_gland MDA 3.74662 1.90559 2.10369e-09 3.10408e-06 DataSet_01_257
PABPC4L SOX4 shRNA Mammary_gland MDA-MB-231 0.23204 -2.10755 4.32575e-06 0.00185 DataSet_01_260
PABPC4L SIX4 siRNA Ovary PEO1 0.51231 -0.9649 0.01211 0.07782 DataSet_01_269
PABPC4L ZIC5 siRNA Skin A375 0.50789 -0.97743 - - DataSet_01_284
PABPC4L POSTN shRNA Brain GSC272 2.5051 1.32487 0.08956 0.54319 DataSet_01_293
PABPC4L TFAP4 siRNA Brain BE(2)-C 0.35123 -1.50952 0.5408 0.55944 DataSet_01_295
PABPC4L PTEN shRNA Lung HCC827 0.48922 -1.03144 0.34211 0.74908 DataSet_01_302
PABPC4L PTEN shRNA Mammary_gland SKBR3 1.57508 0.65542 0.51196 0.8276 DataSet_01_303
PABPC4L RUNX1 shRNA Embryo H9 0.45615 -1.13242 6.22746e-06 0.00229 DataSet_01_314
PABPC4L ELK3 shRNA Mammary_gland MDA-MB-231 7.79597 2.96273 1.66481e-07 1.36895e-05 DataSet_01_318
PABPC4L STAT3 siRNA Liver LX-2 0.59079 -0.75929 0.00047 0.00381 DataSet_01_334
PABPC4L PAX3 shRNA Soft_tissue Rh30 0.61406 -0.70355 - - DataSet_01_359
PABPC4L SOX17 siRNA Umbilical_vein HUVEC 1.69564 0.76183 - - DataSet_01_360
PABPC4L GTF2B siRNA Cervix HeLa 0.64923 -0.62319 - - DataSet_01_362
PABPC4L TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.51724 -0.95109 0.9634 0.99292 DataSet_02_129
PABPC4L PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.58621 -0.77052 0.02282 0.0698 DataSet_02_131
PABPC4L AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.62745 -0.67243 0.03695 0.1569 DataSet_02_132
PABPC4L RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 0.64286 -0.63743 0.01993 0.26029 DataSet_02_138
PABPC4L FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.65217 -0.61667 0.05303 0.15856 DataSet_02_147
PABPC4L PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.54639 -0.87199 0.02141 0.10062 DataSet_02_158
PABPC4L U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.64925 -0.62315 0.02468 0.09382 DataSet_02_170
PABPC4L MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 0.5873 -0.76783 0.18194 1 DataSet_02_183
PABPC4L AR siRNA Prostate abl cells 2.65 1.40599 0.392743560617491 0.999852161656754 DataSet_03_004
PABPC4L ASCL1 siRNA Lung DMS79 1.50833 0.592955 0.187643168060748 0.828013100186986 DataSet_03_016
PABPC4L BCL6 siRNA Lymph OCI-Ly7 DLBCL 2.7301 1.44895 0.186759823354701 0.80231333311012 DataSet_03_025
PABPC4L FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.19906 -2.32873 - - DataSet_03_096
PABPC4L GATA4 siRNA Stomach KatoIII 0.289618 -1.78777 0.320583082641665 0.935201600037567 DataSet_03_106
PABPC4L HNF4a siRNA Liver HepG2 1.60331 0.68105 0.309571106067096 0.859123716068413 DataSet_03_126
PABPC4L KLF5 siRNA Stomach KatoIII 1.59371 0.672388 0.677422952256867 0.900472287221315 DataSet_03_150
PABPC4L KLF5 siRNA Stomach YCC3 1.71934 0.781857 0.628269852990895 0.863271098673203 DataSet_03_151
PABPC4L MYC siRNA Colon HT29 0.134661 -2.8926 - - DataSet_03_177
PABPC4L NR2F2 siRNA Uterus Primary eutopic stromal cells 1.52774 0.611401 0.147537740101789 0.99947668859931 DataSet_03_202
PABPC4L PBX1 siRNA Mammary_gland MCF7 2.25915 1.17578 1.18941816671195e-08 6.85937456742781e-05 DataSet_03_209
PABPC4L PHB shRNA Embryo Embryonic stem cells (ESCs) 0.599634 -0.737847 0.0287007058483157 0.0727256944939476 DataSet_03_211
PABPC4L PPARG siRNA Peripheral_blood GM-CSF Macrophage 1.73708 0.796667 0.0586803568614543 0.859074593625825 DataSet_03_214
PABPC4L SOX2 CRISPR Seminoma-like TCam-2 1.67875 0.747385 0.235047182443675 0.999580851453413 DataSet_03_244
PABPC4L SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.405405 -1.30256 - - DataSet_03_246
PABPC4L SP1 siRNA Ovary OVSAYO 0.242998 -2.04099 0.104325086982325 0.390882668636218 DataSet_03_251
PABPC4L STAT3 CRISPR Embryo hESC 2.54399 1.34709 0.0128220609085286 0.0704371497485178 DataSet_03_258
PABPC4L TP63 siRNA Skin Primary neonatal keratinocytes 1.74973 0.807133 0.00114923966792202 0.0114523571296288 DataSet_03_281
PABPC4L ZNF750 siRNA Skin Primary neonatal keratinocytes 1.75215 0.809126 0.107068892138433 0.307422017933938 DataSet_03_294
PABPC4L MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.618182 -0.693897 0.101719570485435 0.156584211275916 DataSet_04_012
PABPC4L NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 73.9546 6.20857 0.0731494702246443 0.175273827274859 DataSet_04_014
PABPC4L NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.418182 -1.2578 0.0432087756445384 0.0852488264155924 DataSet_04_015
PABPC4L DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.81818 0.862496 0.421442334342299 0.585809323400347 DataSet_02_14
PABPC4L HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.363636 -1.45943 0.749326439957795 0.94675493785481 DataSet_02_45
PABPC4L NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.68182 0.750022 0.639359209861396 0.803673328620396 DataSet_02_32
PABPC4L HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.463636 -1.10893 0.0626136311086141 0.121890033247164 DataSet_04_059
PABPC4L CNOT3 shRNA Lung A549 4.21614 2.07592 3.207578e-01 0.8903147 DataSet_03_340
PABPC4L EZH2 knockdown Uterus Ishikawa (ISK) cell 0.4954 -1.01333 - - DataSet_03_324
PABPC4L ACTR5 siRNA Muscle RD 1.70701 0.771474 - - DataSet_03_343
PABPC4L PBX1 siRNA Mammary_gland MCF7 2.25915 1.17578 1.678742e-08 7.716789e-05 DataSet_03_326
PABPC4L TET1 CRISPR Mammary_gland Hs578T 2.05048 1.03596 8.086083e-03 4.195859e-02 DataSet_03_355
PABPC4L PTPN14 CRISPR Brain U5-NPC 2.72222 1.44478 3.542916e-02 0.26465378 DataSet_03_357
PABPC4L TP53 CRISPR Brain U5-NPC 2.05882 1.04182 1.038485e-01 2.399859e-01 DataSet_03_358
PABPC4L RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 2.41753 1.27354 3.654991e-02 2.195557e-01 DataSet_03_359
PABPC4L USP22 shRNA Liver PLC_PRF_5 cells 0.333333 -1.58496 4.098051e-01 0.62040721 DataSet_03_368
PABPC4L TPR shRNA Bone_marrow U2OS 1.71824 0.780931 1.001906e-01 4.686930e-01 DataSet_03_370
PABPC4L ZFP36L1 siRNA Urinary_bladder J82 3.42246 1.77503 - - DataSet_03_371
PABPC4L E2F1 siRNA Nasopharynx HK1 0.378173 -1.40288 8.605475e-04 1.889462e-02 DataSet_03_373
PABPC4L EZH2 CRISPR Ovary SKOV3 1.87425 0.906315 2.241242e-02 0.1210013520 DataSet_03_378
PABPC4L NFKB2 siRNA Bone_marrow U2OS 0.427807 -1.22497 1.511979e-01 0.47021567 DataSet_03_381
PABPC4L DNMT1 siRNA Skin Human melanoma cells 0.49378 -1.01806 9.293957e-04 2.971193e-03 DataSet_03_382
PABPC4L NFKBIA shRNA Bone_marrow U2OS 0.57153 -0.807099 5.394381e-01 0.87005461 DataSet_03_389
PABPC4L ILF2 siRNA Stomach SGC-7901 2.26667 1.18057 0.2140998097 0.40346604 DataSet_03_393
PABPC4L RELA CRISPR Brain T30 1.68892 0.756104 0.4296142112 0.8400824 DataSet_03_399
PABPC4L HMGA1 shRNA Bile_duct HUCCT1 6.4375 2.6865 2.280326e-02 0.180760659 DataSet_03_400
PABPC4L JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.62745 0.702614 7.797772e-01 0.8522011 DataSet_03_403
PABPC4L E2F6 shRNA Liver HuH7 0.2798 -1.83753 - - DataSet_03_412
PABPC4L USP7 shRNA Skin xenograft cells 0.480374 -1.05777 0.25955722 0.4348960 DataSet_03_431
PABPC4L POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 2 1 6.607549e-01 0.789153159 DataSet_03_434
PABPC4L DAXX shRNA Mammary_gland MDA-MB-231 0.268478 -1.89712 3.701676e-01 0.67624177 DataSet_03_441
PABPC4L PURA siRNA Cervix HeLa 1.76049 0.815977 9.173071e-03 0.091221753 DataSet_03_444
PABPC4L CAMTA1 knockout Embryo_kidney HEK293T 2.0578 1.04111 5.137410e-02 0.18789654 DataSet_03_448
PABPC4L CBX2 siRNA Mammary_gland MDA-MB-231 0.56904 -0.813398 2.332131e-02 8.672509e-02 DataSet_03_450
PABPC4L OGT siRNA Embryo BeWo cells 1.7 0.765535 4.178164e-01 0.75295123 DataSet_03_453
PABPC4L SMARCA2 shRNA Lung HCC2302 0.204841 -2.28742 2.155584e-10 1.594890e-09 DataSet_03_455
PABPC4L IRF2 shRNA Cord_Blood CD34+ cells 2.20968 1.14384 - - DataSet_03_460
PABPC4L TXNIP shRNA Cord_Blood CD34+ cells 2.16129 1.11189 - - DataSet_03_461
PABPC4L SOX9 knockout Liver HuH7 4.59155 2.19898 6.279909e-04 6.659152e-03 DataSet_03_463
PABPC4L SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.67634 0.745313 - - DataSet_03_467
PABPC4L SMARCA1 shRNA Embryo_kidney HEK293T 0.635719 -0.653539 - - DataSet_03_468
PABPC4L EZH2 siRNA Prostate LNCaP 4 2 4.626521e-01 1.0000000 DataSet_03_475
Regulation Region
 
T(co)Fs that significantly regulate PBX1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of PABPC4L
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines