Gene Overview
Target Gene: REEP5
NCBI Official Symbol: REEP5
Entrez ID: 7905
Ensembl ID: ENSG00000129625
Gene Full Name: receptor accessory protein 5
Strand: -
Gene Locus: 5q22.2
External Links:

REEP5 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate REEP5   
T(co)Fs that Repress REEP5
The Intensity of the Gene Regulated by T(co)Fs:
REEP5-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
REEP5 FOXA1 shRNA Prostate 22RV1 0.60252 -0.73091 - - DataSet_01_105
REEP5 ARID1A shRNA Ovary OSE4 0.6252 -0.6776 - - DataSet_01_108
REEP5 ID1 siRNA Lung A549 0.45697 -1.12983 0.00164 0.09442 DataSet_01_117
REEP5 ID1 siRNA Lung H1650 0.41438 -1.27099 0.00082 0.32206 DataSet_01_118
REEP5 ZIC2 siRNA Pancreas PANC1 0.44643 -1.1635 - - DataSet_01_121
REEP5 ID1 shRNA Neuroepithelium GSC2 0.53178 -0.91111 9.02279e-12 2.86479e-10 DataSet_01_133
REEP5 ID1 shRNA Neuroepithelium GSC8 0.40331 -1.31002 6.31293e-13 1.8369e-11 DataSet_01_134
REEP5 ELK1 siRNA Peripheral_blood CD4+ T cells 366.695 8.51844 0.0366 0.12767 DataSet_01_162
REEP5 JUN siRNA Peripheral_blood CD4+ T cells 870.998 9.76653 0.00768 0.05782 DataSet_01_164
REEP5 MAF siRNA Peripheral_blood CD4+ T cells 636.696 9.31446 0.01127 0.11366 DataSet_01_165
REEP5 NFATC3 siRNA Peripheral_blood CD4+ T cells 403.859 8.65771 0.07291 0.28003 DataSet_01_166
REEP5 STAT3 siRNA Peripheral_blood CD4+ T cells 189.726 7.56777 0.19374 0.99183 DataSet_01_168
REEP5 ESRRG siRNA Placenta_tissue Trophoblast cells 0.33134 -1.59363 0.00015 0.01155 DataSet_01_173
REEP5 GATA2 siRNA Prostate LNCaP 1.71154 0.7753 0.00022 0.00184 DataSet_01_193
REEP5 STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 1.57113 0.6518 0.00123 0.00833 DataSet_01_239
REEP5 EGR2 siRNA Neuroepithelium SK-N-MC 0.65845 -0.60285 0.08767 0.69629 DataSet_01_243
REEP5 MYT1L shRNA Fetal_spinal_cord SPC04 0.64932 -0.623 0.00031 0.05587 DataSet_01_264
REEP5 TP53 shRNA Haematopoietic_and_lymphoid_tissue JVM2 1.7174 0.78023 2.04032e-07 7.35858e-06 DataSet_01_286
REEP5 TFAP4 siRNA Brain BE(2)-C 0.21457 -2.22045 0.36815 0.51625 DataSet_01_295
REEP5 SOX17 siRNA Umbilical_vein HUVEC 0.62941 -0.66792 0.10885 0.99998 DataSet_01_300
REEP5 ERG siRNA Cervix HeLa 0.25695 -1.96047 1.80465e-22 5.40887e-20 DataSet_01_316
REEP5 GTF2B siRNA Cervix HeLa 1.59627 0.67471 - - DataSet_01_362
REEP5 RBM17 shRNA Liver HepG2 0.61201 -0.70838 0.02623 0.26938 DataSet_02_100
REEP5 FIP1L1 shRNA Liver HepG2 1.83906 0.87897 0.00077 0.01352 DataSet_02_103
REEP5 U2AF2 shRNA Liver HepG2 1.93528 0.95254 0.95085 0.97192 DataSet_02_105
REEP5 ZNF622 shRNA Liver HepG2 2.14673 1.10214 0.00033 0.00615 DataSet_02_108
REEP5 RBM39 shRNA Liver HepG2 0.65742 -0.60511 0.04586 0.24856 DataSet_02_111
REEP5 PTBP1 shRNA Liver HepG2 1.92207 0.94266 0.00493 0.01465 DataSet_02_120
REEP5 FUS shRNA Liver HepG2 1.84833 0.88622 0.00355 0.06329 DataSet_02_124
REEP5 SNRNP70 shRNA Liver HepG2 1.82606 0.86874 0.01515 0.06211 DataSet_02_126
REEP5 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 1.53778 0.62085 0.14865 0.43458 DataSet_02_129
REEP5 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.14375 1.10014 0.00055 0.02779 DataSet_02_131
REEP5 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.6239 0.69946 0.0146 0.19832 DataSet_02_144
REEP5 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 1.54885 0.6312 0.54077 0.71788 DataSet_02_163
REEP5 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 1.5057 0.59044 0.20195 1 DataSet_02_182
REEP5 E2F7 siRNA Upper_aerodigestive_tract SCC25 0.450564 -1.1502 8.367726012093e-09 2.05291944112315e-06 DataSet_03_063
REEP5 ESR1 siRNA Mammary_gland MCF7 1.61109 0.688034 6.66379640885257e-05 0.00472360066719516 DataSet_03_071
REEP5 FOXA1 siRNA Mammary_gland MCF7 2.14566 1.10142 1.44960217329805e-05 0.000521160157686763 DataSet_03_080
REEP5 GATA3 siRNA Mammary_gland MCF7 0.536718 -0.897762 0.0241006695542756 0.136182306342904 DataSet_03_103
REEP5 JARID1A siRNA Autonomic_ganglia SKNBE2 1.61761 0.69386 0.00149033756260825 0.187135558512686 DataSet_03_135
REEP5 JUN siRNA Skin Ma-Mel-15 1.57506 0.655405 0.00635271747080122 0.514766499186304 DataSet_03_143
REEP5 KDM3A siRNA Mammary_gland MCF7 3.51077 1.81179 2.41535845025357e-07 0.00024352302720347 DataSet_03_146
REEP5 Klf4 siRNA Skin Primary neonatal keratinocytes 2.13299 1.09287 0.000378811983674708 0.00496571317268218 DataSet_03_147
REEP5 MITF siRNA Skin SK-MEL-5 0.386072 -1.37306 3.32363694809443e-09 1.71989180441745e-07 DataSet_03_168
REEP5 MYCN CRISPR Neuroblastoma CHP-134 0.63444 -0.656446 6.39307851523653e-06 0.000437586438815779 DataSet_03_183
REEP5 MYCN CRISPR Neuroblastoma CHP-134 0.63444 -0.656446 6.39307851523653e-06 0.000437586438815779 DataSet_03_184
REEP5 NFAT5 siRNA Synovial Primary fibroblast-like synoviocytes 1.70802 0.772329 0.000616381370794441 0.0483643627097691 DataSet_03_194
REEP5 PBX1 siRNA Mammary_gland LTED 0.40276 -1.31201 4.94378734219398e-05 0.644454904907285 DataSet_03_208
REEP5 PBX1 siRNA Mammary_gland MCF7 0.464015 -1.10776 9.28767282717227e-08 0.000200857534478634 DataSet_03_209
REEP5 RARA siRNA Mammary_gland MCF7 0.659973 -0.599522 0.000394553102719234 0.0191303514315271 DataSet_03_218
REEP5 RELB siRNA Immortalized_keratinocyte HaCaT 3.52338 1.81696 2.67798065120141e-06 6.31222660033183e-05 DataSet_03_227
REEP5 SP1 siRNA Mammary_gland MDA-MB-231 1.75675 0.812913 0.304260412009405 0.51050821604028 DataSet_03_250
REEP5 SRF siRNA Prostate LNCaP 0.66454 -0.589572 0.00351396329189114 0.0265787199042622 DataSet_03_254
REEP5 TP63 siRNA Skin Primary neonatal keratinocytes 1.62933 0.704278 0.00683314291240498 0.0369559714705619 DataSet_03_281
REEP5 ZNF750 siRNA Skin Primary neonatal keratinocytes 2.12329 1.0863 0.000653923488707122 0.0260052133138878 DataSet_03_294
REEP5 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 0.466749 -1.09928 0.169125010693538 0.303641855005735 DataSet_04_014
REEP5 NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.587958 -0.766215 0.0112445036194804 0.0348348197921616 DataSet_04_015
REEP5 YBX1 CRISPR Liver HepG2 0.386931 -1.36985 0.268851785169468 0.972884761036538 DataSet_04_039
REEP5 CNOT7 CRISPR Liver HepG2 0.653274 -0.614241 7.4726691675774e-05 0.00989897872298064 DataSet_04_045
REEP5 ABT1 shRNA Liver HepG2 1.98311 0.987766 0.000484840403384571 0.00560040119303583 DataSet_04_052
REEP5 CALR shRNA Liver HepG2 1.64303 0.71636 0.000840063488476226 0.00923079974611582 DataSet_04_053
REEP5 CNOT7 shRNA Liver HepG2 1.7518 0.80884 0.00051723704786417 0.00490899210457589 DataSet_04_051
REEP5 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.517517 -0.950321 0.000189296253349728 0.0108014837024223 DataSet_02_34
REEP5 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.607535 -0.718962 0.0114692445926677 0.0716359490773946 DataSet_04_064
REEP5 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.63366 -0.65822 0.0027259983023197 0.0123249050041982 DataSet_04_059
REEP5 EZH2 siRNA Uterus Hec-1A 1.80667 0.853333 1.467170e-06 4.643666e-04 DataSet_03_314
REEP5 TET1 siRNA Lung A549 0.588841 -0.76405 - - DataSet_03_318
REEP5 TET1 siRNA Lung A549 0.588841 -0.76405 - - DataSet_03_320
REEP5 SMARCA4 siRNA Colon HCT116 1.51982 0.603905 1.769690e-02 0.1525852 DataSet_03_302
REEP5 EZH2 siRNA Ovary SKOV3 1.63779 0.71175 4.399383e-04 3.603565e-02 DataSet_03_325
REEP5 PBX1 siRNA Mammary_gland MCF7 0.464015 -1.10776 1.277751e-07 2.391077e-04 DataSet_03_326
REEP5 ETV5 knockdown Colon HT29 0.492118 -1.02292 1.400135e-03 0.049972955 DataSet_03_353
REEP5 CREBBP CRISPR Brain U5-NPC 2.32763 1.21886 0.2358547344 0.7490853 DataSet_03_356
REEP5 TP53 CRISPR Brain U5-NPC 2.57282 1.36335 1.001532e-02 1.623145e-01 DataSet_03_358
REEP5 DNMT3A knockout Embryo_kidney HEK293T 2.02093 1.01502 - - DataSet_03_369
REEP5 ZFP36L1 siRNA Urinary_bladder J82 3.3455 1.74222 - - DataSet_03_371
REEP5 TRIM8 siRNA Mammary_gland MCF7 0.495935 -1.01178 7.021683e-05 0.0035208444 DataSet_03_388
REEP5 PRDM15 CRISPR Kidney Immortalized human podocytes 1.59601 0.674466 1.217680e-06 1.323213e-04 DataSet_03_391
REEP5 KDM5A CRISPR Lung GLC16 0.640418 -0.642914 4.434371e-03 0.028430848 DataSet_03_392
REEP5 ILF2 siRNA Stomach SGC-7901 1.61152 0.688424 0.2615147809 0.45928020 DataSet_03_393
REEP5 EHF shRNA Stomach MKN7 8.64228 3.11141 - - DataSet_03_402
REEP5 CDK7 shRNA Bone_marrow D458 1.84515 0.883735 1.404890e-01 0.46545280 DataSet_03_404
REEP5 USP22 shRNA Liver HuH7 1.55094 0.633141 - - DataSet_03_411
REEP5 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 0.640869 -0.641899 2.778639e-02 0.110884533 DataSet_03_418
REEP5 USP7 shRNA Skin xenograft cells 0.467784 -1.09608 0.26801963 0.4348960 DataSet_03_431
REEP5 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.608888 -0.715752 - - DataSet_03_432
REEP5 SETDB1 shRNA Colon HCT116 1.6148 0.691359 - - DataSet_03_440
REEP5 CBX2 siRNA Mammary_gland MDA-MB-231 1.7612 0.816556 2.145974e-08 2.706742e-05 DataSet_03_450
REEP5 CBX2 siRNA Mammary_gland MCF7 1.66334 0.734082 2.733697e-03 0.0113866209 DataSet_03_451
REEP5 SMARCA2 shRNA Lung HCC2302 1.59922 0.677371 2.929130e-10 2.077120e-09 DataSet_03_455
REEP5 IRF2 shRNA Cord_Blood CD34+ cells 1.61611 0.692529 - - DataSet_03_460
REEP5 TXNIP shRNA Cord_Blood CD34+ cells 2.51947 1.33312 - - DataSet_03_461
REEP5 TXNIP shRNA Cord_blood ST3 1.91911 0.940438 1.307774e-02 0.1706945454 DataSet_03_462
REEP5 SOX9 knockout Liver HuH7 0.527176 -0.923643 3.160012e-04 4.382641e-03 DataSet_03_463
REEP5 SMARCA1 Cas13 Embryo_kidney HEK293T 0.582112 -0.780631 - - DataSet_03_466
REEP5 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.6195 0.695553 - - DataSet_03_467
Regulation Region
 
T(co)Fs that significantly regulate PBX1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of REEP5
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines