Gene Overview
Target Gene: SERTAD3
NCBI Official Symbol: SERTAD3
Entrez ID: 29946
Ensembl ID: ENSG00000167565
Gene Full Name: SERTA domain containing 3
Strand: -
Gene Locus: 19q13.2
External Links:

SERTAD3 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate SERTAD3   
T(co)Fs that Repress SERTAD3
The Intensity of the Gene Regulated by T(co)Fs:
SERTAD3-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
SERTAD3 ZIC2 siRNA Pancreas PANC1 2.50955 1.32743 - - DataSet_01_121
SERTAD3 ID1 shRNA Neuroepithelium GSC8 1.87129 0.90404 1.30817e-10 8.07961e-10 DataSet_01_134
SERTAD3 TFAP2C shRNA Mammary_gland MCF7 0.36262 -1.46348 2.62838e-11 8.27352e-10 DataSet_01_150
SERTAD3 MYCN siRNA Autonomic_ganglia SKNBE2 1.7356 0.79543 0.01459 0.1587 DataSet_01_160
SERTAD3 TCF4 siRNA Autonomic_ganglia SH-SY5Y 1.74373 0.80218 0.00407 0.05583 DataSet_01_185
SERTAD3 GABPA shRNA Prostate C4-2B 1984.55 10.9546 0.23577 0.43934 DataSet_01_190
SERTAD3 GABPA shRNA Prostate LNCaP 643.386 9.32954 0.46147 0.7048 DataSet_01_191
SERTAD3 TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.6599 -0.59969 - - DataSet_01_196
SERTAD3 XBP1 shRNA Mammary_gland T47D 1.8873 0.91633 1.71622e-05 0.00051 DataSet_01_203
SERTAD3 ERG siRNA Prostate VCaP 1.62323 0.69887 3.53352e-05 0.00229 DataSet_01_216
SERTAD3 ETS1 siRNA Haematopoietic_and_lymphoid_tissue ALLSIL 1.55522 0.63712 0.07941 0.64074 DataSet_01_244
SERTAD3 YBX1 shRNA Mammary_gland MDA 0.65247 -0.61602 3.0593e-05 3e-04 DataSet_01_259
SERTAD3 POSTN shRNA Brain GSC272 2.21629 1.14815 0.09851 0.54681 DataSet_01_293
SERTAD3 TFAP4 siRNA Brain BE(2)-C 0.09885 -3.3386 0.21417 0.51625 DataSet_01_295
SERTAD3 SOX9 siRNA Prostate VCaP 1.52911 0.61269 0.26771 0.93253 DataSet_01_308
SERTAD3 SOX9 siRNA Prostate VCaP 1.52911 0.61269 0.26771 0.93253 DataSet_01_309
SERTAD3 MYC siRNA Colon HCT116 1.83055 0.87227 3.20535e-06 2.25666e-05 DataSet_01_324
SERTAD3 KLF4 siRNA Embryo HCE 1.59601 0.67447 0.00544 0.37336 DataSet_01_341
SERTAD3 CDX2 siRNA Colon COLO320 0.44566 -1.166 - - DataSet_01_357
SERTAD3 PAX3 shRNA Soft_tissue Rh30 0.64594 -0.63054 - - DataSet_01_359
SERTAD3 GTF2B siRNA Cervix HeLa 2.10887 1.07647 - - DataSet_01_362
SERTAD3 RBM17 shRNA Liver HepG2 1.80182 0.84945 0.09638 0.3571 DataSet_02_100
SERTAD3 RBFOX2 shRNA Liver HepG2 1.60364 0.68135 0.15973 0.65738 DataSet_02_101
SERTAD3 RBM25 shRNA Liver HepG2 1.85209 0.88915 0.0081 0.03612 DataSet_02_119
SERTAD3 PTBP1 shRNA Liver HepG2 1.96249 0.97268 0.00458 0.01399 DataSet_02_120
SERTAD3 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.65708 -0.60586 0.11325 0.33265 DataSet_02_140
SERTAD3 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 2.81339 1.49231 0.00147 0.02045 DataSet_02_143
SERTAD3 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.56579 0.64689 0.00499 0.08524 DataSet_02_147
SERTAD3 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 1.51497 0.59929 0.00523 0.06227 DataSet_02_168
SERTAD3 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.59723 0.67557 0.11234 1 DataSet_02_178
SERTAD3 BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 1.59128 0.67019 0.1106 1 DataSet_02_186
SERTAD3 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.51135 0.59584 0.20689 1 DataSet_02_204
SERTAD3 ATR siRNA Mammary_gland MCF7 0.639014 -0.646081 0.154044271423505 0.999819450785634 DataSet_03_020
SERTAD3 BCL6 siRNA Mammary_gland MCF7 0.66471 -0.589203 0.187947613952603 0.989541443114508 DataSet_03_024
SERTAD3 CDK2 siRNA Mammary_gland MCF7 0.658165 -0.603479 0.178842389724563 0.99987175116756 DataSet_03_044
SERTAD3 CEBPD siRNA Mammary_gland MCF7 0.569538 -0.812135 0.085326539885673 0.999848455332859 DataSet_03_050
SERTAD3 CHEK1 siRNA Mammary_gland MCF7 0.594396 -0.750504 0.106344894447773 0.999587656258211 DataSet_03_053
SERTAD3 CREBBP siRNA Mammary_gland MCF7 0.632758 -0.660274 0.146526763396998 0.966455540764243 DataSet_03_055
SERTAD3 ERF siRNA Mammary_gland MCF7 0.591566 -0.75739 0.10376297448789 0.999855523449227 DataSet_03_067
SERTAD3 ESRRA siRNA Mammary_gland MCF7 1.56272 0.644057 0.155145152909596 0.999964003642835 DataSet_03_072
SERTAD3 FOS siRNA Mammary_gland MCF7 0.571604 -0.806912 0.0869347654471881 0.999966427400474 DataSet_03_079
SERTAD3 FOXC1 siRNA Mammary_gland MCF7 0.586584 -0.769591 0.0993389771849817 0.999669928105298 DataSet_03_084
SERTAD3 HDAC3 siRNA Mammary_gland MCF7 0.634735 -0.655774 0.148871634091587 0.99997791025972 DataSet_03_114
SERTAD3 HDAC5 siRNA Mammary_gland MCF7 0.654521 -0.61149 0.173912489032602 0.999966625300244 DataSet_03_115
SERTAD3 HOXB7 siRNA Mammary_gland MCF7 1.67322 0.742628 0.109374859249892 0.999977683706165 DataSet_03_127
SERTAD3 JUND siRNA Mammary_gland MCF7 0.66003 -0.599397 0.237835170643004 0.999848956486105 DataSet_03_145
SERTAD3 KDM3A siRNA Mammary_gland MCF7 1.66651 0.736827 0.00170105565989316 0.0275391624191943 DataSet_03_146
SERTAD3 MAPK14 siRNA Mammary_gland MCF7 0.638246 -0.647816 0.357051935462378 0.999824418484635 DataSet_03_157
SERTAD3 MAX siRNA Mammary_gland MCF7 0.641196 -0.641163 0.156733046661195 0.999907009675999 DataSet_03_158
SERTAD3 MYB siRNA Cord_Blood CD34+ progenitor cells 1.94947 0.963081 - - DataSet_03_170
SERTAD3 MYCN siRNA Autonomic_ganglia SKNBE2 1.7356 0.795434 0.0140375673430054 0.161923786357852 DataSet_03_185
SERTAD3 NCOR2 siRNA Mammary_gland MCF7 0.645786 -0.630873 0.162502373615773 0.999834929103349 DataSet_03_193
SERTAD3 NMI siRNA Mammary_gland MCF7 0.592988 -0.753926 0.105053909508492 0.711292853383598 DataSet_03_199
SERTAD3 NR4A3 siRNA Pancreas 1.1B4 1.61455 0.691131 2.68331801539959e-05 0.000304552041514703 DataSet_03_203
SERTAD3 PHB shRNA Embryo Embryonic stem cells (ESCs) 0.653764 -0.613158 0.0134901638004669 0.0399794029148912 DataSet_03_211
SERTAD3 RBL2 siRNA Mammary_gland MCF7 0.603121 -0.729482 0.114622687833908 0.999927471951507 DataSet_03_220
SERTAD3 RELA siRNA Mammary_gland MCF7 0.607381 -0.719326 0.118843910479679 0.999993711976373 DataSet_03_224
SERTAD3 SMAD7 siRNA Mammary_gland MCF7 0.565713 -0.821858 0.0824116659410057 0.99858912864726 DataSet_03_234
SERTAD3 SP100 siRNA Mammary_gland MCF7 2.27753 1.18747 0.0228722990970537 0.999952086018951 DataSet_03_252
SERTAD3 SRF siRNA Prostate LNCaP 1.7924 0.841891 2.04869128394553e-07 1.60740615050146e-05 DataSet_03_254
SERTAD3 STAT1 siRNA Mammary_gland MCF7 0.648971 -0.623774 0.166597742842227 0.999890411872485 DataSet_03_256
SERTAD3 TP53 siRNA Mammary_gland MCF7 0.588802 -0.764145 0.101290381725066 0.999938217444253 DataSet_03_277
SERTAD3 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 1.92006 0.941149 0.0740746562353579 0.732269517420315 DataSet_03_282
SERTAD3 WT1 siRNA Mammary_gland MCF7 0.501803 -0.994807 0.0445591197741659 0.999957852801679 DataSet_03_285
SERTAD3 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 0.585501 -0.772255 0.196505639670888 0.336515907936396 DataSet_04_014
SERTAD3 NFX1 CRISPR Liver HepG2 1.63242 0.707009 0.00385576405409138 0.0217432735850461 DataSet_04_032
SERTAD3 CNOT7 shRNA Liver HepG2 1.66306 0.733843 0.00542585675962931 0.0190191852125677 DataSet_04_051
SERTAD3 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.6617 -0.595751 0.00148766567665246 0.0175554160252624 DataSet_02_34
SERTAD3 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.5298 -0.916481 0.00017380194066945 0.0125682918939438 DataSet_02_35
SERTAD3 SMARCA4 siRNA Colon HCT116 1.87944 0.910306 7.497422e-02 8.868714e-01 DataSet_03_301
SERTAD3 ELF3 knockdown Bile_duct HBDEC2 1.53714 0.620251 1.081004e-04 7.361426e-03 DataSet_03_305
SERTAD3 ARID3B CRISPR Colon HCT15 1.59064 0.66961 - - DataSet_03_335
SERTAD3 ETV5 knockdown Colon HT29 0.618659 -0.692784 1.004912e-02 0.115240038 DataSet_03_353
SERTAD3 PARP1 siRNA Prostate LNCaP 0.630562 -0.66529 4.150717e-04 0.035544990 DataSet_03_354
SERTAD3 CREBBP CRISPR Brain U5-NPC 1.61265 0.689437 0.7407050093 0.8386546 DataSet_03_356
SERTAD3 PTPN14 CRISPR Brain U5-NPC 0.502975 -0.991442 5.775207e-02 0.28251891 DataSet_03_357
SERTAD3 ZFP36L1 siRNA Urinary_bladder J82 3.1413 1.65136 - - DataSet_03_371
SERTAD3 HNRNPU siRNA Colon RKO 0.658883 -0.601906 - - DataSet_03_374
SERTAD3 EZH2 CRISPR Ovary SKOV3 1.5881 0.667299 3.336607e-02 0.1535284717 DataSet_03_378
SERTAD3 YY1 shRNA Brain GSC1517 1.6859 0.753517 - - DataSet_03_384
SERTAD3 ILF2 siRNA Stomach SGC-7901 1.91815 0.939719 0.2496896120 0.44509719 DataSet_03_393
SERTAD3 HMGA1 shRNA Bile_duct HUCCT1 1.51297 0.597386 1.600915e-02 0.151762231 DataSet_03_400
SERTAD3 EHF shRNA Stomach MKN7 0.121027 -3.0466 - - DataSet_03_402
SERTAD3 CDK7 shRNA Bone_marrow D458 1.52063 0.604674 1.616798e-01 0.49537519 DataSet_03_404
SERTAD3 USP22 shRNA Liver HuH7 0.295987 -1.75639 - - DataSet_03_411
SERTAD3 FOXK2 shRNA Ovary OVCAR-5 0.575955 -0.795971 3.193879e-02 0.14584782 DataSet_03_419
SERTAD3 USP7 shRNA Skin xenograft cells 0.442784 -1.17532 0.26034663 0.4348960 DataSet_03_431
SERTAD3 SUFU shRNA Mammary_gland HCC1954 cells 1.78055 0.832325 0.1509549826 0.6455297 DataSet_03_437
SERTAD3 SETDB1 shRNA Colon HCT116 2.91117 1.5416 - - DataSet_03_440
SERTAD3 CBX2 siRNA Mammary_gland MCF7 1.62074 0.69665 5.142367e-04 0.0036147654 DataSet_03_451
SERTAD3 TXNIP shRNA Cord_blood ST3 0.596154 -0.746243 6.033288e-01 0.7493927496 DataSet_03_462
SERTAD3 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.50181 1.32297 - - DataSet_03_467
SERTAD3 SMARCA1 shRNA Embryo_kidney HEK293T 1.54348 0.626185 - - DataSet_03_468
Regulation Region
 
T(co)Fs that significantly regulate SP100 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of SERTAD3
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines