Gene Overview
Target Gene: TBX22
NCBI Official Symbol: TBX22
Entrez ID: 50945
Ensembl ID: ENSG00000122145
Gene Full Name: T-box 22
Strand: +
Gene Locus: Xq21.1
External Links:

TBX22 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate TBX22   
T(co)Fs that Repress TBX22
The Intensity of the Gene Regulated by T(co)Fs:
TBX22-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
TBX22 ID1 siRNA Lung A549 2.55914 1.35566 0.08156 0.2866 DataSet_01_117
TBX22 ID1 siRNA Lung H1650 0.52913 -0.9183 0.58416 0.82091 DataSet_01_118
TBX22 BRD4 shRNA Embryo_kidney HEK293 1.7106 0.7745 - - DataSet_01_119
TBX22 ZIC2 siRNA Pancreas PANC1 1.56541 0.64654 - - DataSet_01_121
TBX22 FOXM1 siRNA Central_nervous_system U87 2.73276 1.45036 - - DataSet_01_122
TBX22 POLR3A siRNA Mammary_gland MCF7 3.85714 1.94753 - - DataSet_01_139
TBX22 TP53 siRNA Lung SAECs 2.41667 1.27302 0.05702 0.41799 DataSet_01_175
TBX22 GABPA shRNA Prostate C4-2B 1372.33 10.4224 0.23735 0.43934 DataSet_01_190
TBX22 GABPA shRNA Prostate LNCaP 1381.7 10.4322 0.46061 0.7048 DataSet_01_191
TBX22 CREB1 shRNA Parotid_gland H3118 MEC 5.38592 2.42919 0.43042 0.74924 DataSet_01_194
TBX22 CREB1 shRNA Parotid_gland HSY 0.25837 -1.9525 0.8475 0.98718 DataSet_01_195
TBX22 TP63 siRNA Head_and_neck SCC-1 6.76829 2.75879 - - DataSet_01_199
TBX22 TP63 siRNA Immortalized_keratinocyte HaCaT 3.46377 1.79234 - - DataSet_01_200
TBX22 TP63 siRNA Head_and_neck SCC-012 0.33459 -1.57955 - - DataSet_01_201
TBX22 TP63 siRNA Head_and_neck SCC-6 2.11828 1.08289 - - DataSet_01_202
TBX22 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 5.28365 2.40154 - - DataSet_01_210
TBX22 SNAI2 shRNA Skin Primary human keratinocytes 0.51133 -0.96768 0.65341 0.75521 DataSet_01_225
TBX22 KLF2 shRNA Bone_marrow RPMI8226 0.50239 -0.99312 0.27742 0.82659 DataSet_01_226
TBX22 POSTN shRNA Brain GSC272 3.40618 1.76815 0.38376 0.6991 DataSet_01_293
TBX22 TFAP4 siRNA Brain BE(2)-C 0.30487 -1.71372 0.50198 0.53363 DataSet_01_295
TBX22 PTEN shRNA Skin A431 0.51612 -0.95422 0.28487 0.48606 DataSet_01_301
TBX22 PTEN shRNA Lung HCC827 0.17197 -2.5398 0.09672 0.60043 DataSet_01_302
TBX22 PTEN shRNA Mammary_gland SKBR3 3.42825 1.77747 0.58023 0.85484 DataSet_01_303
TBX22 GATA3 siRNA Oral_cavity OEC-M1 0.52154 -0.93916 0.09083 0.99787 DataSet_01_347
TBX22 ZFX siRNA Prostate C4-2B 0.17647 -2.5025 0.03012 0.07133 DataSet_02_172
TBX22 AR siRNA Prostate abl cells 2.22857 1.15612 0.19433394183167 0.999852161656754 DataSet_03_004
TBX22 ASCL1 siRNA Lung DMS79 10 3.32193 0.00252855213655948 0.577978708511504 DataSet_03_016
TBX22 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.652463 -0.616032 0.695875572211315 0.953338043288894 DataSet_03_025
TBX22 BCL6 siRNA Lymph Pfeiffer DLBCL 1.68923 0.756363 0.544632395000227 0.859622049105679 DataSet_03_026
TBX22 GATA4 siRNA Stomach KatoIII 0.464165 -1.10729 0.270075576498133 0.924237866158102 DataSet_03_106
TBX22 GATA4 siRNA Stomach YCC3 0.20061 -2.31754 0.154098955516567 0.695424360256517 DataSet_03_107
TBX22 GATA6 siRNA Stomach AGS 2.45997 1.29864 0.450176759252475 0.843375527434238 DataSet_03_108
TBX22 GATA6 siRNA Stomach KatoIII 2.62735 1.39361 0.328161344038682 0.794358808982524 DataSet_03_109
TBX22 GATA6 siRNA Stomach YCC3 0.388287 -1.3648 0.373886178585641 0.868644051081322 DataSet_03_110
TBX22 HNF4a siRNA Liver HepG2 7.5 2.90689 0.140556912504909 0.762067871531399 DataSet_03_126
TBX22 KLF5 siRNA Stomach KatoIII 1.6725 0.74201 0.643900507649056 0.889548037839892 DataSet_03_150
TBX22 MEF2D shRNA Liver HuH7 1.62629 0.701585 - - DataSet_03_162
TBX22 MEF2D siRNA Liver HuH7 16.7299 4.06436 - - DataSet_03_163
TBX22 MYC siRNA Colon HT29 0.327839 -1.60894 - - DataSet_03_177
TBX22 MYCN siRNA Brain BE(2)C cells 1.61653 0.6929 - - DataSet_03_188
TBX22 NR2F2 siRNA Uterus Primary eutopic stromal cells 0.108421 -3.20528 0.0242835033853972 0.99947668859931 DataSet_03_202
TBX22 PHB shRNA Embryo Embryonic stem cells (ESCs) 2.64463 1.40307 0.0568476446563251 0.12502344634309 DataSet_03_211
TBX22 SOX2 siRNA Embryo 2102Ep 5.5218 2.46514 2.70390735019054e-09 1.49880159570919e-06 DataSet_03_242
TBX22 SOX2 siRNA Embryo NTera-2 1.58976 0.66881 0.000223989587749976 0.0118785913266679 DataSet_03_243
TBX22 SP1 siRNA Mammary_gland MDA-MB-231 0.345984 -1.53122 0.101040342686548 0.413972819854456 DataSet_03_250
TBX22 STAT6 siRNA Umbilical_vein HUVEC 3.8 1.926 0.239851668200848 0.862294572327306 DataSet_03_264
TBX22 TFE3 siRNA Kidney UOK257-2 2.50126 1.32265 - - DataSet_03_275
TBX22 BRCA1 siRNA Mammary_gland MCF7 0.381285 -1.39106 2.801057e-01 0.9999931 DataSet_03_308
TBX22 E2F1 siRNA Nasopharynx HK1 0.583333 -0.777608 5.404242e-01 1.000000e+00 DataSet_03_373
TBX22 ZNF213 siRNA Mammary_gland MCF7 2.10316 1.07256 7.769666e-01 9.149356e-01 DataSet_03_376
TBX22 NFKBIA shRNA Bone_marrow U2OS 0.0893658 -3.48413 1.661862e-01 0.87005461 DataSet_03_389
TBX22 TFAP2A knockout Embryo H9 2 1 2.812777e-01 0.42275578 DataSet_03_405
TBX22 CHD1 shRNA Prostate LNCaP 3.42857 1.77761 8.957841e-03 2.152945e-01 DataSet_03_407
TBX22 USP7 shRNA Skin xenograft cells 0.513158 -0.962525 0.24850678 0.4348960 DataSet_03_431
TBX22 CIC knockout Brain Immortalized Astrocyte Cells 0.5 -1 6.852342e-01 8.942591e-01 DataSet_03_438
TBX22 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.333333 -1.58496 3.953288e-01 0.90558273 DataSet_03_439
TBX22 PARP1 knockout Embryo_kidney HEK293a 0.25 -2 6.110465e-01 7.066398e-01 DataSet_03_464
TBX22 LIN28A siRNA Mammary_gland MCF7M 0.456999 -1.12974 8.917470e-01 0.9936218 DataSet_03_469
TBX22 LIN28A siRNA Mammary_gland MCF7M 0.456999 -1.12974 8.917470e-01 0.9936218 DataSet_03_470
Regulation Region
 
T(co)Fs that significantly regulate BCL11A by the evidences of both expression and ChIP-seq/motif
Expression Atlas of TBX22
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines