Gene Overview
Target Gene: TTC39C
NCBI Official Symbol: TTC39C
Entrez ID: 125488
Ensembl ID: ENSG00000168234
Gene Full Name: tetratricopeptide repeat domain 39C
Strand: +
Gene Locus: 18q11.2
External Links:

TTC39C Significantly Regulated by These T(co)Fs

T(co)Fs that Activate TTC39C   
T(co)Fs that Repress TTC39C
The Intensity of the Gene Regulated by T(co)Fs:
TTC39C-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
TTC39C ZIC2 siRNA Pancreas PANC1 1.51474 0.59907 - - DataSet_01_121
TTC39C LIN28B siRNA Embryo_kidney HEK293 0.33228 -1.58952 1.37949e-05 0.0063 DataSet_01_153
TTC39C ELK1 siRNA Peripheral_blood CD4+ T cells 0.30018 -1.73612 0.87526 0.94046 DataSet_01_162
TTC39C GATA3 siRNA Peripheral_blood CD4+ T cells 5.95339 2.57371 0.38148 0.70727 DataSet_01_163
TTC39C JUN siRNA Peripheral_blood CD4+ T cells 2.64592 1.40377 0.61749 0.79921 DataSet_01_164
TTC39C MAF siRNA Peripheral_blood CD4+ T cells 0.01303 -6.2623 0.38755 0.73288 DataSet_01_165
TTC39C NFATC3 siRNA Peripheral_blood CD4+ T cells 2.0814 1.05755 0.673 0.85878 DataSet_01_166
TTC39C NFKB1 siRNA Peripheral_blood CD4+ T cells 9.38763 3.23076 0.11681 0.67337 DataSet_01_167
TTC39C STAT3 siRNA Peripheral_blood CD4+ T cells 0.01348 -6.21253 0.39582 0.99183 DataSet_01_168
TTC39C ESRRG siRNA Placenta_tissue Trophoblast cells 1.70047 0.76594 0.02326 0.21222 DataSet_01_173
TTC39C FOXA1 siRNA Prostate LNCaP 1.87454 0.90654 0.00032 0.03547 DataSet_01_233
TTC39C YBX1 shRNA Mammary_gland MDA 0.53117 -0.91276 9.99539e-09 6.82319e-07 DataSet_01_255
TTC39C YBX1 shRNA Mammary_gland MDA 0.41469 -1.26991 8.56582e-07 0.00012 DataSet_01_257
TTC39C SOX4 shRNA Mammary_gland MDA-MB-231 1.57686 0.65705 0.00271 0.05953 DataSet_01_260
TTC39C SIX4 siRNA Ovary PEO1 3.22063 1.68734 7.49518e-05 0.00307 DataSet_01_269
TTC39C ZIC5 siRNA Skin A375 1.54603 0.62857 - - DataSet_01_284
TTC39C ZIC5 siRNA Skin SK-MEL-28 1.89913 0.92534 - - DataSet_01_285
TTC39C TFAP4 siRNA Brain BE(2)-C 0.26875 -1.89567 0.46902 0.51914 DataSet_01_295
TTC39C SOX7 siRNA Umbilical_vein HUVEC 0.65401 -0.61261 0.10816 0.89788 DataSet_01_299
TTC39C PTEN shRNA Skin A431 0.65649 -0.60715 0.01134 0.10013 DataSet_01_301
TTC39C HIF1A siRNA Oral_cavity OEC-M1 1.69374 0.76021 0.04143 0.85151 DataSet_01_348
TTC39C RBM17 shRNA Liver HepG2 0.60917 -0.71507 0.10752 0.3694 DataSet_02_100
TTC39C SAFB2 shRNA Liver HepG2 1.62148 0.69731 0.00364 0.02715 DataSet_02_102
TTC39C FIP1L1 shRNA Liver HepG2 0.63506 -0.65504 0.00226 0.02032 DataSet_02_103
TTC39C HDGF shRNA Liver HepG2 0.55256 -0.85581 0.00233 0.06599 DataSet_02_104
TTC39C U2AF2 shRNA Liver HepG2 1.7201 0.78249 0.35069 0.49954 DataSet_02_105
TTC39C SSB shRNA Liver HepG2 2.01708 1.01227 0.00543 0.01805 DataSet_02_107
TTC39C RBM39 shRNA Liver HepG2 0.56615 -0.82076 0.06593 0.27931 DataSet_02_111
TTC39C BCLAF1 shRNA Liver HepG2 1.7452 0.80339 0.0153 0.06098 DataSet_02_112
TTC39C PCBP1 shRNA Liver HepG2 0.66262 -0.59376 0.01303 0.03825 DataSet_02_115
TTC39C HNRNPLL shRNA Liver HepG2 2.21698 1.14859 0.00187 0.01531 DataSet_02_125
TTC39C TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 4.25 2.08746 0.00126 0.23905 DataSet_02_129
TTC39C PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.25 1.16993 0.00137 0.02779 DataSet_02_131
TTC39C SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.03988 0.26384 DataSet_02_133
TTC39C SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 5.25 2.39232 0.02301 0.11691 DataSet_02_134
TTC39C PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 12.5 3.64386 0.19382 0.34853 DataSet_02_135
TTC39C HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 10.25 3.35755 0.0042 0.14579 DataSet_02_136
TTC39C PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 20.5 4.35755 0.00077 0.18403 DataSet_02_137
TTC39C RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 0.07692 -3.70044 0.01929 0.26029 DataSet_02_138
TTC39C RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.00115 0.20864 DataSet_02_141
TTC39C BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.07273 -3.78136 0.00765 0.10306 DataSet_02_142
TTC39C RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.14286 -2.80735 0.0194 0.05348 DataSet_02_143
TTC39C DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 0.06061 -4.04439 0.22979 0.5719 DataSet_02_145
TTC39C FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.6 -0.73697 0.66099 0.76914 DataSet_02_147
TTC39C SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.03226 -4.9542 0.06159 0.48872 DataSet_02_150
TTC39C RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.27273 -1.87447 0.87821 0.93498 DataSet_02_151
TTC39C ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.04167 -4.58496 0.01233 0.25114 DataSet_02_152
TTC39C FUS shRNA Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.01183 0.22733 DataSet_02_155
TTC39C HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.45455 -1.1375 0.61104 0.8133 DataSet_02_156
TTC39C PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 76 6.24793 0.12295 0.2372 DataSet_02_158
TTC39C AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.02043 0.53443 DataSet_02_162
TTC39C SSB shRNA Haematopoietic_and_lymphoid_tissue K562 2.25 1.16993 0.05082 0.23796 DataSet_02_164
TTC39C EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.12195 -3.03562 0.13226 0.35072 DataSet_02_167
TTC39C RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 11.25 3.49185 0.29275 0.42646 DataSet_02_168
TTC39C TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.03571 -4.80735 0.00069 0.04354 DataSet_02_169
TTC39C U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.66667 1.87447 0.03605 0.1137 DataSet_02_170
TTC39C RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 14.3333 3.8413 0.24403 0.44948 DataSet_02_171
TTC39C MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.55882 -0.83954 0.65791 1 DataSet_02_173
TTC39C LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 0.19231 -2.37851 0.0847 1 DataSet_02_175
TTC39C CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.16 -2.64386 0.11142 1 DataSet_02_176
TTC39C VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.51111 -0.96829 0.14273 1 DataSet_02_179
TTC39C ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 1.9375 0.9542 0.82328 1 DataSet_02_180
TTC39C STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 0.52 -0.94342 0.89177 1 DataSet_02_182
TTC39C MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 0.09375 -3.41504 0.00662 1 DataSet_02_183
TTC39C BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 0.52941 -0.91754 0.01722 1 DataSet_02_186
TTC39C BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.06 -4.05889 0.02613 1 DataSet_02_188
TTC39C MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 0.36 -1.47393 0.07618 1 DataSet_02_189
TTC39C RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 0.2963 -1.75489 0.90957 1 DataSet_02_190
TTC39C LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.03846 -4.70044 0.00842 1 DataSet_02_191
TTC39C MAX siRNA Haematopoietic_and_lymphoid_tissue K562 0.64 -0.64386 0.53906 1 DataSet_02_192
TTC39C ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.11765 -3.08746 0.00572 1 DataSet_02_193
TTC39C TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.94829 1 DataSet_02_194
TTC39C LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.04 -4.64386 0.0168 1 DataSet_02_195
TTC39C CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.26 -1.94342 0.30379 1 DataSet_02_197
TTC39C UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 0.14706 -2.76553 0.04538 1 DataSet_02_198
TTC39C TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.27027 -1.88753 0.45471 1 DataSet_02_201
TTC39C BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.35294 -1.5025 0.22128 1 DataSet_02_202
TTC39C ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 4.25 2.08746 0.05733 1 DataSet_02_203
TTC39C RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.6 -0.73697 0.44867 1 DataSet_02_204
TTC39C E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 0.34 -1.55639 0.54379 1 DataSet_02_205
TTC39C BCL6 siRNA Lymph Pfeiffer DLBCL 2.1495 1.104 0.00189618188984133 0.18911606855337 DataSet_03_026
TTC39C CENPF siRNA Mammary_gland MCF7 1.5057 0.590436 0.0866378746338549 0.999662524742916 DataSet_03_052
TTC39C GATA3 siRNA Mammary_gland MCF7 1.52984 0.613383 0.0774406919065054 0.999831535534034 DataSet_03_102
TTC39C GATA3 siRNA Mammary_gland MCF7 1.50882 0.593419 0.108167230461668 0.25246080179619 DataSet_03_103
TTC39C Klf4 siRNA Skin Primary neonatal keratinocytes 3.05997 1.61352 0.000660702693097667 0.00704127156720257 DataSet_03_147
TTC39C MITF siRNA Skin MZ7 3.33503 1.7377 8.5342306533425e-13 8.45961709391613e-11 DataSet_03_165
TTC39C MITF siRNA Skin Ma-Mel-15 1.95063 0.963941 0.0271423028495158 0.328801336459043 DataSet_03_166
TTC39C MITF siRNA Skin Ma-Mel-15 1.77578 0.828457 0.00563576962037376 0.095683947651632 DataSet_03_167
TTC39C MYCN siRNA Brain BE(2)C cells 0.506067 -0.9826 - - DataSet_03_188
TTC39C PHB shRNA Embryo Embryonic stem cells (ESCs) 0.293106 -1.7705 1.27053383188837e-05 0.00041311426620935 DataSet_03_211
TTC39C RELB siRNA Immortalized_keratinocyte HaCaT 0.541057 -0.886146 0.000518067949050183 0.00485147149473191 DataSet_03_227
TTC39C SOX2 siRNA Embryo NTera-2 0.639618 -0.644718 0.000120701571367596 0.00780570356391387 DataSet_03_243
TTC39C STAT3 CRISPR Embryo hESC 1.73286 0.793159 0.00299272998739413 0.0393086162600926 DataSet_03_258
TTC39C STAT6 siRNA Umbilical_vein HUVEC 1.64557 0.718587 0.308514015905548 0.876741320594925 DataSet_03_264
TTC39C TP53 knockout Haematopoietic_and_lymphoid_tissue MM1S 1.64024 0.71391 0.109670506477363 0.994828053448528 DataSet_03_279
TTC39C ZNF750 siRNA Skin Primary neonatal keratinocytes 3.02274 1.59586 0.00624357919011327 0.0638621144254673 DataSet_03_294
TTC39C APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 5.42857 2.44057 0.00145238635419007 0.287551764612054 DataSet_04_001
TTC39C FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.233333 -2.09954 0.0159322839045612 0.077619812956107 DataSet_04_010
TTC39C NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 36.2683 5.18064 0.630440067000957 0.741281632947214 DataSet_04_014
TTC39C NPM1 shRNA Liver HepG2 0.647185 -0.627749 0.120225518398236 0.499292071268128 DataSet_04_058
TTC39C ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.181818 -2.45943 0.464407748688054 0.669371880700527 DataSet_04_048
TTC39C NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 7 2.80735 0.538240757168989 0.71871692816812 DataSet_04_046
TTC39C RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.419753 -1.25239 0.204586259667241 0.708274573662385 DataSet_04_076
TTC39C SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.57143 1.36257 0.567383780995702 1 DataSet_04_077
TTC39C SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 7.85714 2.974 0.0165150649053685 0.473368010655576 DataSet_04_073
TTC39C SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.71429 0.777608 0.75082789740884 0.929291073064613 DataSet_04_075
TTC39C SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 8.28571 3.05063 0.107901239339428 0.218446827233314 DataSet_04_049
TTC39C DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.390244 -1.35755 0.351645881612345 0.514245524717986 DataSet_02_14
TTC39C HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 8.25 3.04439 0.0410506415831295 0.405123309920551 DataSet_02_75
TTC39C LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.585366 -0.77259 0.506418376036606 0.682505677834825 DataSet_02_35
TTC39C NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.57317 1.36355 0.156742899576359 0.456661818419083 DataSet_02_32
TTC39C SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.585366 -0.77259 0.506482832335727 0.660687691960169 DataSet_02_47
TTC39C SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.292683 -1.77259 0.289971497480991 0.696313733988711 DataSet_02_49
TTC39C TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.390244 -1.35755 0.314044119135546 0.501835231777451 DataSet_02_43
TTC39C TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.585366 -0.77259 0.487190053680696 0.649988138371443 DataSet_02_53
TTC39C ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.116529953178809 0.238226258961604 DataSet_04_060
TTC39C CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.0208333 -5.58496 0.26146597841175 0.457179253012049 DataSet_04_061
TTC39C DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 7.5 2.90689 0.385508146343057 0.773882841277463 DataSet_04_063
TTC39C HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.0833333 -3.58496 0.0634819495560417 0.123260785387981 DataSet_04_059
TTC39C UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.222222 -2.16992 0.168982450819092 0.405402725100008 DataSet_04_062
TTC39C EZH2 knockdown Uterus Ishikawa (ISK) cell 2.01857 1.01333 - - DataSet_03_324
TTC39C TET1 CRISPR Mammary_gland MDA-MB-231 0.379124 -1.39926 5.506457e-04 8.612943e-03 DataSet_03_347
TTC39C PARP1 siRNA Prostate LNCaP 0.568044 -0.815927 4.523992e-03 0.094664232 DataSet_03_354
TTC39C CREBBP CRISPR Brain U5-NPC 2 1 0.4829254105 0.7505923 DataSet_03_356
TTC39C PTPN14 CRISPR Brain U5-NPC 0.659091 -0.601451 4.503442e-01 0.66128882 DataSet_03_357
TTC39C TP53 CRISPR Brain U5-NPC 2.15385 1.10692 4.319893e-02 1.767578e-01 DataSet_03_358
TTC39C RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 1.56477 0.645953 2.146509e-02 1.851750e-01 DataSet_03_359
TTC39C ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 0.501913 -0.994491 5.317481e-04 2.088715e-03 DataSet_03_362
TTC39C MYC siRNA Peripheral_blood T lymphocyte 0.264707 -1.91753 6.859528e-01 0.850660914 DataSet_03_363
TTC39C DNMT3A knockout Embryo_kidney HEK293T 1.65461 0.726489 - - DataSet_03_369
TTC39C ZFP36L1 siRNA Urinary_bladder J82 2.2638 1.17875 - - DataSet_03_371
TTC39C EZH2 CRISPR Ovary SKOV3 2.47406 1.30688 1.101446e-03 0.0222472703 DataSet_03_378
TTC39C NFKBIA shRNA Bone_marrow U2OS 0.289838 -1.78668 4.010857e-01 0.87005461 DataSet_03_389
TTC39C ILF2 siRNA Stomach SGC-7901 1.65185 0.724084 0.3489716832 0.55004493 DataSet_03_393
TTC39C ASXL1 CRISPR Embryo iPSC 1.50842 0.593033 0.0830406215 0.8048302 DataSet_03_394
TTC39C TFAP2A knockout Embryo H9 1.9019 0.927438 5.088293e-03 0.04991890 DataSet_03_405
TTC39C E2F6 shRNA Liver HuH7 0.608071 -0.717687 - - DataSet_03_412
TTC39C FOXK2 shRNA Ovary OVCAR-5 0.646288 -0.62975 1.213359e-01 0.31561202 DataSet_03_419
TTC39C MAEL CRISPR Liver Alexander cells 4.20023 2.07047 - - DataSet_03_423
TTC39C FOXP3 CRISPR Peripheral_blood Naive Treg 0.665015 -0.588542 1.394757e-01 0.485921028 DataSet_03_427
TTC39C USP7 shRNA Skin xenograft cells 0.437051 -1.19413 0.25981964 0.4348960 DataSet_03_431
TTC39C POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 2.23554 1.16063 6.535770e-05 0.040206003 DataSet_03_434
TTC39C POU2AF1 CRISPR Lymph SUDHL4 2.56965 1.36157 2.234015e-03 0.017522875 DataSet_03_435
TTC39C EP300 knockout Pancreas HPAF-II orthotopic cells 0.629178 -0.668459 6.894192e-03 3.207651e-02 DataSet_03_436
TTC39C SETDB1 shRNA Colon HCT116 0.538067 -0.894144 - - DataSet_03_440
TTC39C SMARCA2 shRNA Lung HCC2302 3.82723 1.9363 1.848530e-15 9.301436e-14 DataSet_03_455
TTC39C IRF2 shRNA Cord_Blood CD34+ cells 1.82622 0.868864 - - DataSet_03_460
TTC39C TXNIP shRNA Cord_Blood CD34+ cells 2.26316 1.17834 - - DataSet_03_461
TTC39C SMARCA1 Cas13 Embryo_kidney HEK293T 0.482289 -1.05203 - - DataSet_03_466
TTC39C SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.57312 0.653624 - - DataSet_03_467
TTC39C APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 5.42857 2.44057 0.03313585 0.4304265 DataSet_04_072
Regulation Region
 
T(co)Fs that significantly regulate CNOT7 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of TTC39C
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines