Gene Overview
| Target Gene: | Tff3 |
| NCBI Official Symbol: | Tff3 |
| Entrez ID: | 21786 |
| Ensembl ID: | ENSMUSG00000024029 |
| Gene Full Name: | trefoil factor 3, intestinal |
| Strand: | - |
| Gene Locus: | 17 A3.3|17 15.8 cM |
| External Links: |
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Tff3 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Tff3
T(co)Fs
that Repress Tff3
The Intensity of the Gene Regulated by T(co)Fs:
Tff3-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Tff3 | Ahr | knockout | Liver | Liver | 50.6953 | 5.66378 | 3.2919622924735e-12 | 9.75408427259897e-09 | DataSet_11_002 |
| Tff3 | Arid1a | knockout | Liver | Liver | 3.15506 | 1.65767 | 0.549253409238263 | 0.999999999999956 | DataSet_11_004 |
| Tff3 | Arid1a | knockout | Ovary | Ovary | 1.50624 | 0.590952 | 0.306259078880347 | 0.94648870498129 | DataSet_11_005 |
| Tff3 | Atoh1 | knockout | Gastrointestinal_tissue | Intestinal epithelial Lgr5(hi) stem cells | 0.0115154 | -6.44029 | 9.60599101184134e-07 | 0.00161545421369194 | DataSet_11_010 |
| Tff3 | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.617647 | -0.695145 | 0.187959334841446 | 0.566129627439398 | DataSet_11_014 |
| Tff3 | Elf5 | knockout | Mammary_gland | Mammary gland | 0.324427 | -1.62403 | 0.0600734245139695 | 0.328628362508208 | DataSet_11_035 |
| Tff3 | Foxp1 | knockout | Eye | Lens | 0.347295 | -1.52577 | - | - | DataSet_11_044 |
| Tff3 | Gata3 | siRNA | Peripheral_blood | CD4+ T helper (Th) cells | 0.388388 | -1.36443 | 0.349236125452002 | 0.987135756219234 | DataSet_11_048 |
| Tff3 | Hsf4 | knockout | Eye | Lens | 0.303086 | -1.7222 | 0.214097927625582 | 0.987999303842427 | DataSet_11_058 |
| Tff3 | Irf6 | knockout | Skin | Skin | 1.52526 | 0.609056 | 0.186001049143724 | 0.503044433471115 | DataSet_11_062 |
| Tff3 | Lhx8 | knockout | Ovary | Ovary | 1.65392 | 0.725894 | 0.655672263400549 | 0.781389244724821 | DataSet_11_070 |
| Tff3 | Lmx1b | knockout | Kidney | Kidney | 0.39176 | -1.35196 | 0.476708905238833 | 0.758131009376662 | DataSet_11_072 |
| Tff3 | Meis1 | knockout | Hematopoietic | KSL hematopoietic cells | 0.648876 | -0.623984 | 0.25290413342753 | 0.995635220774426 | DataSet_11_081 |
| Tff3 | Neurod1 | knockout | Eye | Retina | 0.614555 | -0.702385 | 0.179443890203202 | 0.363106900166303 | DataSet_11_088 |
| Tff3 | Npas4 | RNAi | Brain | Hippocampal Neurons | 0.580172 | -0.785447 | 0.019835264312012 | 0.0979998135053454 | DataSet_11_093 |
| Tff3 | Nr2f2 | knockout | Ovary | E14.5 Ovary | 1.72319 | 0.785082 | 0.150629689095056 | 0.836069454533427 | DataSet_11_094 |
| Tff3 | Nrf1 | knockdown | Liver | Liver | 5.12955 | 2.35883 | 0.00554189798196449 | 0.0368358859332209 | DataSet_11_096 |
| Tff3 | Otx2 | knockout | Eye | Retina | 1.68343 | 0.751401 | 0.971841253142486 | 0.999923528647439 | DataSet_11_097 |
| Tff3 | Pitx2 | knockout | Eye | Cornea | 0.422966 | -1.24139 | 0.00313331877152581 | 0.0893811419581343 | DataSet_11_103 |
| Tff3 | Prdm2 | shRNA | Muscle | C2C12 | 1.67578 | 0.744832 | 0.336724012096822 | 0.963242451950825 | DataSet_11_108 |
| Tff3 | Prox1 | knockout | Liver | Liver | 3.18474 | 1.67118 | - | - | DataSet_11_109 |
| Tff3 | Runx1 | knockout | Lymph | ProB cells | 1.61193 | 0.688788 | 0.0671020193525628 | 0.282008568752404 | DataSet_11_116 |
| Tff3 | Runx1 | knockout | Mammary_gland | Luminal epithelial cells | 0.307417 | -1.70173 | 0.0472407284042864 | 0.999784944667092 | DataSet_11_117 |
| Tff3 | Runx2 | knockout | Humeri | Embryonic humeri | 2.73248 | 1.45021 | 0.117954516092347 | 0.998727525190751 | DataSet_11_118 |
| Tff3 | Smad4 | knockout | Aorta | Aortic arteries | 25.1891 | 4.65473 | 0.0181867135089431 | 0.208379117644689 | DataSet_11_128 |
| Tff3 | Snai1 | knockout | Embryo | Embryoid body | 0.0580851 | -4.10569 | - | - | DataSet_11_129 |
| Tff3 | Sox11 | knockout | Brain | Cortex | 0.649059 | -0.623578 | - | - | DataSet_11_138 |
| Tff3 | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 0.581073 | -0.78321 | 0.564783318860433 | 0.924261066168849 | DataSet_11_152 |
| Tff3 | Tbx1 | knockout | Ear | Otic vesicles | 1.64814 | 0.720837 | 0.618567693114499 | 0.929083389303195 | DataSet_11_155 |
| Tff3 | Vdr | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.36157 | -1.46765 | 0.0988345749361775 | 0.999827445128963 | DataSet_11_174 |
| Tff3 | Xbp1 | siRNA | Liver | Liver | 3.02899 | 1.59883 | 0.129463034893757 | 0.386894224861972 | DataSet_11_181 |
| Tff3 | Dnmt1 | siRNA | Pituitary_gland | AtT-20 | 0.289335 | -1.78919 | 3.750822e-03 | 0.8131470 | DataSet_11_187 |
| Tff3 | Cpeb1 | siRNA | Neuron | Neuro-2a | 1.79858 | 0.846861 | - | - | DataSet_11_189 |
| Tff3 | Hipk2 | knockout | Heart | cardiac tissue | 2.0084 | 1.00604 | 2.740028e-02 | 2.174777e-01 | DataSet_11_238 |
| Tff3 | Kdm5b | knockout | Heart | left ventricles | 3.30755 | 1.72576 | 0.0008322754 | 0.9999827 | DataSet_11_210 |
| Tff3 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 0.410341 | -1.2851 | 7.702074e-04 | 1.204996e-02 | DataSet_11_192 |
| Tff3 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 0.64554 | -0.631422 | - | - | DataSet_11_196 |
| Tff3 | Dnmt3a | siRNA | Peritoneum | peritoneal macrophages | 2.76053 | 1.46494 | - | - | DataSet_11_222 |
| Tff3 | Bcl11b | knockout | Main_olfactory_epithelium | main olfactory epithelium (MOE) | 1.61633 | 0.692723 | - | - | DataSet_11_207 |
| Tff3 | Dux | siRNA | Embryo | ES cells | 1.72222 | 0.784271 | 2.804495e-01 | 0.8774371149 | DataSet_11_239 |
| Tff3 | Ncl | siRNA | Embryo | ES cells | 1.66667 | 0.736966 | 3.206648e-01 | 0.6196502073 | DataSet_11_240 |
| Tff3 | Eed | knockout | Brain | Forebrain | 2.07534 | 1.05335 | 8.314194e-03 | 2.430786e-01 | DataSet_11_258 |
| Tff3 | Eed | knockout | Brain | hindbrain | 10.8876 | 3.44461 | 2.419804e-03 | 2.114082e-01 | DataSet_11_259 |
| Tff3 | Eed | knockout | Brain | midbrain | 1.81511 | 0.860056 | 9.466080e-02 | 9.156792e-01 | DataSet_11_260 |
| Tff3 | Eed | knockout | Spinal_cord | spinal cord | 3.09568 | 1.63026 | 6.571885e-02 | 9.999790e-01 | DataSet_11_261 |
| Tff3 | Bcl3 | knockout | Bone | Osteoblast | 0.5 | -1 | 5.553937e-01 | 8.088142e-01 | DataSet_11_263 |
| Tff3 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 914.298 | 9.83652 | 1.005806e-03 | 0.05796889 | DataSet_11_272 |
| Tff3 | Ssrp1 | CRISPR | Embryo | ES cells | 0.333333 | -1.58496 | 6.308313e-01 | 0.8882485 | DataSet_11_278 |
| Tff3 | Pdx1 | CRISPR | Liver | Liver | 0.344 | -1.53952 | 8.371637e-02 | 0.396148877 | DataSet_11_286 |
| Tff3 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 4.82857 | 2.2716 | 8.156435e-01 | 9.476761e-01 | DataSet_11_297 |
| Tff3 | Phf8 | knockout | prostate | Prostate | 277.32 | 8.11541 | 0.0964707532 | 0.3368299 | DataSet_11_298 |
| Tff3 | Satb2 | knockout | Colon | Intestine epithelium | 2.95261 | 1.56199 | 1.017861e-03 | 0.0540286485 | DataSet_11_316 |
| Tff3 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.496124 | -1.01123 | 7.102554e-02 | 3.949298e-01 | DataSet_11_319 |
| Tff3 | Ezh2 | knockout | Eye | Retina | 2.64721 | 1.40447 | 0.6691862365 | 1.0000000 | DataSet_11_334 |
| Tff3 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 2.09924 | 1.06986 | 0.1196077282 | 0.1926526 | DataSet_11_341 |
Regulation Region
Expression Atlas of Tff3