Gene Overview
| Target Gene: | Upp2 |
| NCBI Official Symbol: | Upp2 |
| Entrez ID: | 76654 |
| Ensembl ID: | ENSMUSG00000026839 |
| Gene Full Name: | uridine phosphorylase 2 |
| Strand: | + |
| Gene Locus: | 2|2 C1.1 |
| External Links: |
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Upp2 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Upp2
T(co)Fs
that Repress Upp2
The Intensity of the Gene Regulated by T(co)Fs:
Upp2-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Upp2 | Ahr | knockout | Liver | Liver | 2.43033 | 1.28115 | 6.30520865006434e-06 | 0.000628732368322041 | DataSet_11_002 |
| Upp2 | Bcl11a | knockout | Bone_marrow | Bone marrow erythoid progenitors | 0.561483 | -0.832686 | 0.0100011301487424 | 0.249907758174599 | DataSet_11_013 |
| Upp2 | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 1.90821 | 0.932222 | 0.17372914990477 | 0.553616742129962 | DataSet_11_014 |
| Upp2 | Bhlha9 | knockout | Limb | Whole limb bud | 4.55237 | 2.18662 | - | - | DataSet_11_016 |
| Upp2 | Foxp1 | knockout | Eye | Lens | 0.553797 | -0.85257 | - | - | DataSet_11_044 |
| Upp2 | Gata3 | siRNA | Peripheral_blood | CD4+ T helper (Th) cells | 2.19288 | 1.13283 | 0.0751844130212738 | 0.987135756219234 | DataSet_11_048 |
| Upp2 | Gata4 | knockout | Intestine | Jejunum | 0.591837 | -0.756729 | 0.125232661644709 | 0.624917386051946 | DataSet_11_049 |
| Upp2 | Hsf4 | knockout | Eye | Lens | 0.431298 | -1.21324 | 0.775721926678252 | 0.987999303842427 | DataSet_11_058 |
| Upp2 | Junb | shRNA | Tibialis_anterior_muscle | Tibialis anterior muscle | 0.483573 | -1.04819 | 0.175853208368423 | 0.45016421353215 | DataSet_11_065 |
| Upp2 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.405941 | -1.30066 | - | - | DataSet_11_074 |
| Upp2 | Mef2a | shRNA | Muscle | C2C12 | 2.07417 | 1.05253 | 9.9587283656983e-07 | 5.35696596671521e-05 | DataSet_11_077 |
| Upp2 | Nr2f2 | knockout | Ovary | E14.5 Ovary | 0.516396 | -0.953449 | 0.0141933881463175 | 0.773851838642894 | DataSet_11_094 |
| Upp2 | Nr2f2 | knockout | Ovary | E16.5 Ovary | 0.58542 | -0.772456 | 0.534987101037534 | 0.8160460799287 | DataSet_11_095 |
| Upp2 | Nrf1 | knockdown | Liver | Liver | 0.394827 | -1.34071 | 0.0181259573059556 | 0.0626993412014986 | DataSet_11_096 |
| Upp2 | Pitx2 | knockout | Eye | Cornea | 2.70665 | 1.43651 | 0.0113137273482042 | 0.168229903947482 | DataSet_11_103 |
| Upp2 | Plagl2 | knockout | Intestine | Small intestine | 0.477273 | -1.06711 | 0.101302323028043 | 0.371328939165359 | DataSet_11_104 |
| Upp2 | Prox1 | knockout | Liver | Liver | 2.27768 | 1.18757 | - | - | DataSet_11_109 |
| Upp2 | Rest | knockout | Brain | Brain | 0.517467 | -0.95046 | 0.0491775813169847 | 1 | DataSet_11_113 |
| Upp2 | Smad4 | siRNA | Brain | bEnd3 | 2.26273 | 1.17806 | - | - | DataSet_11_127 |
| Upp2 | Smad4 | knockout | Aorta | Aortic arteries | 10.1008 | 3.3364 | 0.102134258435821 | 0.470325775611112 | DataSet_11_128 |
| Upp2 | Spdef | knockout | Stomach | Stomach | 0.523793 | -0.932931 | 0.701146116215272 | 0.952586694604925 | DataSet_11_147 |
| Upp2 | Stat3 | knockout | Lung | Lung typeII cells | 2.47776 | 1.30903 | 0.0728744438970796 | 0.702198270155099 | DataSet_11_151 |
| Upp2 | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 3.31739 | 1.73005 | 0.060548817054847 | 0.810515522259952 | DataSet_11_152 |
| Upp2 | Vdr | knockout | Bone_marrow | Bone marrow-derived macrophages | 1.7684 | 0.822442 | 0.258434939246351 | 0.999827445128963 | DataSet_11_174 |
| Upp2 | Wt1 | siRNA | Embryo_kidney | LB-22 | 1.8117 | 0.857345 | 0.0958437699305201 | 0.28927468453564 | DataSet_11_179 |
| Upp2 | Dnmt1 | siRNA | Pituitary_gland | AtT-20 | 1.94163 | 0.957267 | 2.672748e-01 | 0.9999923 | DataSet_11_187 |
| Upp2 | Pogz | knockdown | Liver | fetal liver | 0.246947 | -2.01772 | 2.881178e-02 | 0.3285648 | DataSet_11_188 |
| Upp2 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 1.79487 | 0.843881 | 1.764095e-01 | 3.442074e-01 | DataSet_11_192 |
| Upp2 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 0.609882 | -0.713399 | - | - | DataSet_11_196 |
| Upp2 | Ezh2 | knockdown | Brain | Brain | 0.61969 | -0.690382 | 3.480868e-02 | 0.2056870363 | DataSet_11_221 |
| Upp2 | Dnmt1 | knockout | Liver | Liver | 0.613074 | -0.705866 | 1.448069e-01 | 4.893513e-01 | DataSet_11_232 |
| Upp2 | Dux | siRNA | Embryo | ES cells | 1.66667 | 0.736966 | 5.137745e-01 | 0.8774371149 | DataSet_11_239 |
| Upp2 | Twist1 | knockout | Bone_marrow | stromal cells | 0.0672498 | -3.89433 | - | - | DataSet_11_244 |
| Upp2 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 0.266667 | -1.90689 | 2.298853e-02 | 0.1777021711 | DataSet_11_245 |
| Upp2 | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 1.62391 | 0.699474 | 5.557972e-01 | 0.730434835 | DataSet_11_252 |
| Upp2 | Crebbp | shRNA | Lung | preSC | 0.361702 | -1.46713 | 1.130058e-02 | 0.31419422 | DataSet_11_255 |
| Upp2 | Ctnnb1 | knockout | Embryo | MGE cells | 2.36093 | 1.23935 | 1.159220e-04 | 0.012271095 | DataSet_11_266 |
| Upp2 | Kat6b | shRNA | Bone_marrow | LT-HSCs | 31 | 4.9542 | 3.233269e-03 | 0.4282073 | DataSet_11_271 |
| Upp2 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 24.1775 | 4.59559 | 3.365462e-03 | 0.12684280 | DataSet_11_272 |
| Upp2 | Ezh2 | siRNA | Bone_marrow | Mesenchymal stem cells | 2 | 1 | 5.861427e-01 | 7.837272e-01 | DataSet_11_276 |
| Upp2 | Usp7 | knockout | Embryo | ES cells | 2.125 | 1.08746 | 1.226412e-01 | 0.5913015 | DataSet_11_279 |
| Upp2 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 1.54909 | 0.631422 | - | - | DataSet_11_285 |
| Upp2 | Ssrp1 | CRISPR | Embryo | ES cells | 0.5 | -1 | 2.739724e-02 | 0.22170999 | DataSet_11_296 |
| Upp2 | Phf8 | knockout | prostate | Prostate | 0.482143 | -1.05247 | 0.1968670415 | 0.4468311 | DataSet_11_298 |
| Upp2 | Hmg20a | siRNA | Hypothalamus | Primary hypothalamic astrocytes | 0.5 | -1 | 0.0092399494 | 0.2412574 | DataSet_11_300 |
| Upp2 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.445545 | -1.16636 | - | - | DataSet_11_305 |
| Upp2 | Jmjd6 | knockout | Bone_marrow | Lin-Sca1+Kit+ (LSK) haematopoietic stem and progenitor cells | 2 | 1 | - | - | DataSet_11_306 |
| Upp2 | Cited2 | knockout | Haematopoietic_and_lymphoid_tissue | Hematopoietic stem cell (HSC) | 2.10526 | 1.074 | - | - | DataSet_11_308 |
| Upp2 | Actl6a | knockout | Nerve | sciatic nerve | 1.61143 | 0.68834 | 3.255871e-02 | 0.250498196 | DataSet_11_314 |
| Upp2 | Satb2 | knockout | Colon | Intestine epithelium | 0.589474 | -0.762501 | 5.491057e-03 | 0.1398958288 | DataSet_11_316 |
| Upp2 | Setdb1 | shRNA | Neuron | NE-4C | 4.77988 | 2.25698 | - | - | DataSet_11_323 |
| Upp2 | Dnmt3l | knockout | Testis | Spermatogonial progenitor cells | 0.605097 | -0.724762 | - | - | DataSet_11_328 |
| Upp2 | Ezh2 | knockout | Eye | Retina | 2.45619 | 1.29642 | 0.8946982478 | 1.0000000 | DataSet_11_334 |
| Upp2 | Dnmt3a | knockout | Peritoneum | peritoneal macrophages | 1.94382 | 0.958897 | - | - | DataSet_11_336 |
| Upp2 | Gtf2ird1 | knockout | Lip | Lip | 0.654639 | -0.611228 | 1.166326e-01 | 5.032000e-01 | DataSet_11_339 |
| Upp2 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.526316 | -0.925999 | 5.627998e-03 | 0.016996401 | DataSet_11_340 |
| Upp2 | Hnrnpk | siRNA | Embryo | ES cells | 0.564097 | -0.825985 | 2.673080e-01 | 0.369646706 | DataSet_11_342 |
| Upp2 | Dux | shRNA | Embryo | ES cells | 0.614286 | -0.703018 | 7.111571e-02 | 5.425219e-01 | DataSet_11_345 |
Regulation Region
Expression Atlas of Upp2