Gene Overview
Target Gene: VWA3A
NCBI Official Symbol: VWA3A
Entrez ID: 146177
Ensembl ID: ENSG00000175267
Gene Full Name: von Willebrand factor A domain containing 3A
Strand: +
Gene Locus: 16p12.2
External Links:

VWA3A Significantly Regulated by These T(co)Fs

T(co)Fs that Activate VWA3A   
T(co)Fs that Repress VWA3A
The Intensity of the Gene Regulated by T(co)Fs:
VWA3A-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
VWA3A AR siRNA Prostate abl cells 0.639121 -0.645838 0.601040583918819 0.999852161656754 DataSet_03_004
VWA3A ARID1A siRNA Mammary_gland MDA-MB-157 1.57884 0.658867 - - DataSet_03_014
VWA3A ASCL1 siRNA Lung DMS79 0.279221 -1.84052 0.102554331202159 0.770244386916434 DataSet_03_016
VWA3A BCL6 siRNA Lymph Pfeiffer DLBCL 0.646752 -0.628715 0.207110348119029 0.682010396643827 DataSet_03_026
VWA3A KLF5 siRNA Stomach KatoIII 2.05218 1.03716 0.0345379612318309 0.387990583256591 DataSet_03_150
VWA3A MEF2D shRNA Liver HuH7 1.68919 0.75633 - - DataSet_03_162
VWA3A PRRX1 CRISPR Neuroblastoma 691-MES 0.464501 -1.10625 0.00153669992177391 0.878656003669909 DataSet_03_217
VWA3A SOX11 siRNA Lung_fibroblast NHLF 0.282873 -1.82177 0.411987656195136 0.626906426787479 DataSet_03_237
VWA3A SOX11 siRNA Lung_fibroblast NHLF 0.275631 -1.85919 0.14032850623328 0.512365867484229 DataSet_03_238
VWA3A TFE3 siRNA Kidney UOK257-2 0.559029 -0.839004 - - DataSet_03_275
VWA3A ZNF746 siRNA Colon HCT116 1.74291 0.8015 - - DataSet_03_293
VWA3A APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.238095 -2.07039 0.0166238854422747 0.467894202746221 DataSet_04_001
VWA3A NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 19.2581 4.26739 0.0962455520935437 0.208670394135278 DataSet_04_014
VWA3A RPS3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.571429 -0.807355 0.290488912012383 0.675176148840809 DataSet_04_017
VWA3A YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.0921053 -3.44057 0.0218124166083803 0.480420090826274 DataSet_04_022
VWA3A CIZ1 CRISPR Liver HepG2 1.625 0.70044 0.50103393857589 0.69607056442153 DataSet_04_026
VWA3A E4F1 CRISPR Liver HepG2 1.55556 0.63743 0.881076474614925 0.948944132378436 DataSet_04_028
VWA3A ERN1 CRISPR Liver HepG2 0.482759 -1.05063 0.317009847432284 0.516801926409455 DataSet_04_029
VWA3A PAN2 CRISPR Liver HepG2 0.416667 -1.26303 0.0577305953164618 0.195890426708569 DataSet_04_033
VWA3A SMAD2 CRISPR Liver HepG2 0.625 -0.678072 0.926358760914965 0.985488580099516 DataSet_04_034
VWA3A SMAD4 CRISPR Liver HepG2 0.2 -2.32193 0.0911663630176696 0.223630720036315 DataSet_04_035
VWA3A SRPK2 CRISPR Liver HepG2 0.517241 -0.95109 0.356423310802559 0.551560969009005 DataSet_04_037
VWA3A WRN shRNA Liver HepG2 0.62069 -0.688056 0.508657506186793 0.705800656769428 DataSet_04_038
VWA3A YBX1 CRISPR Liver HepG2 11.8 3.56071 0.00807370896449121 0.972884761036538 DataSet_04_039
VWA3A ZNF574 CRISPR Liver HepG2 0.5 -1 0.0116632815076722 0.0755318638556184 DataSet_04_041
VWA3A APTX CRISPR Liver HepG2 0.428571 -1.22239 0.44385568877809 0.916061173353702 DataSet_04_069
VWA3A CHCHD3 CRISPR Liver HepG2 0.322581 -1.63227 0.27855270321916 0.623541952632125 DataSet_04_067
VWA3A CNOT7 CRISPR Liver HepG2 1.625 0.70044 0.507786380920102 0.671008273585708 DataSet_04_045
VWA3A PAN2 CRISPR Liver HepG2 0.2 -2.32193 0.239533511880721 0.410042354802371 DataSet_04_066
VWA3A SEPT11 CRISPR Liver HepG2 8 3 0.0534326328951459 0.226034768186008 DataSet_04_068
VWA3A CALR shRNA Liver HepG2 4 2 0.764483198942121 0.861129103561243 DataSet_04_053
VWA3A CCAR1 shRNA Liver HepG2 9.5 3.24793 0.316727993717171 0.474262032019721 DataSet_04_054
VWA3A CNOT7 shRNA Liver HepG2 0.510638 -0.969626 0.34302550572551 0.451156632931823 DataSet_04_051
VWA3A DDX1 shRNA Liver HepG2 0.375 -1.41504 0.247659319502659 0.490075969334382 DataSet_04_057
VWA3A NPM1 shRNA Liver HepG2 2.2 1.1375 0.731610927891077 0.954660231447794 DataSet_04_058
VWA3A UBE2L3 shRNA Liver HepG2 0.25 -2 0.189641781419392 0.321547617332531 DataSet_04_055
VWA3A YBX3 shRNA Liver HepG2 0.25 -2 0.167322534908387 0.340997838537627 DataSet_02_98
VWA3A SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.452852069519985 1 DataSet_04_077
VWA3A CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.58065 0.660514 0.550257911452527 0.761939009935032 DataSet_02_38
VWA3A DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.612903 -0.706269 0.647232531164271 0.785203417000649 DataSet_02_14
VWA3A LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.290323 -1.78427 0.357239712685868 0.540348670491191 DataSet_02_35
VWA3A NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.8871 0.916168 0.38544219453726 0.625980671451775 DataSet_02_32
VWA3A SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.645161 -0.632268 0.679658789706306 0.803622699678113 DataSet_02_47
VWA3A SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.911218885800143 0.996474203139664 DataSet_02_49
VWA3A TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.645161 -0.632268 0.68036463017532 0.825433668105814 DataSet_02_43
VWA3A TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.129032 -2.9542 0.242546696729045 0.385726215424669 DataSet_02_33
VWA3A TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.6129 0.68966 0.380351739974985 0.551438208065955 DataSet_02_53
VWA3A HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.83883149032863 0.908758529409085 DataSet_04_059
VWA3A UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.599746945996815 0.809054535820149 DataSet_04_062
VWA3A DNMT1 siRNA Lung_fibroblast IMR-90 1.54692 0.629403 3.299324e-01 0.9999458 DataSet_03_317
VWA3A AEBP1 siRNA Umbilical_vein HUVEC 1.55254 0.63463 1.273019e-02 0.563238092 DataSet_03_300
VWA3A TET1 CRISPR Mammary_gland Hs578T 1.92265 0.943093 4.713308e-01 6.569658e-01 DataSet_03_355
VWA3A CREBBP CRISPR Brain U5-NPC 0.286487 -1.80346 0.5679152123 0.7615550 DataSet_03_356
VWA3A PTPN14 CRISPR Brain U5-NPC 0.5 -1 5.425144e-01 0.71454579 DataSet_03_357
VWA3A TP53 CRISPR Brain U5-NPC 0.232432 -2.10512 6.038891e-01 6.793437e-01 DataSet_03_358
VWA3A RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 0.212151 -2.23684 2.933185e-01 5.351221e-01 DataSet_03_359
VWA3A ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 1.92452 0.944502 5.161385e-02 9.418951e-02 DataSet_03_362
VWA3A MYC siRNA Peripheral_blood T lymphocyte 2.62829 1.39412 4.871976e-02 0.202392812 DataSet_03_363
VWA3A TP53 knockout Stomach SNU1 1.54302 0.625756 0.9533797650 1.0000000 DataSet_03_365
VWA3A TPR shRNA Bone_marrow U2OS 0.342653 -1.54518 7.112499e-02 3.992156e-01 DataSet_03_370
VWA3A E2F1 siRNA Nasopharynx HK1 2.33333 1.22239 3.571404e-01 9.722824e-01 DataSet_03_373
VWA3A GLI1 siRNA Skeletal_muscle RMS13 3.91258 1.96812 1.725318e-02 0.103465424 DataSet_03_375
VWA3A SMARCA2 shRNA Lung NCI-H1944 1.7 0.765535 1.149842e-01 5.185246e-01 DataSet_03_377
VWA3A EZH2 CRISPR Ovary SKOV3 2.75 1.45943 8.981993e-02 0.2587389415 DataSet_03_378
VWA3A TCF19 CRISPR Oral_squamous CAL27 1.93571 0.952866 7.418631e-01 0.8881756132 DataSet_03_383
VWA3A YY1 shRNA Brain GSC1517 4 2 - - DataSet_03_384
VWA3A TRIM8 siRNA Mammary_gland MCF7 0.538462 -0.893085 6.157334e-01 0.7682312849 DataSet_03_388
VWA3A ILF2 siRNA Stomach SGC-7901 0.5 -1 0.3701861526 0.57377107 DataSet_03_393
VWA3A BMI1 shRNA Bile_duct QBC-939 0.579397 -0.787375 8.467138e-01 0.9241293751 DataSet_03_395
VWA3A IKZF2 CRISPR Lymph CAR T Cell 5.91827 2.56518 3.298096e-01 0.756470688 DataSet_03_397
VWA3A TLE4 CRISPR Lymph CAR T Cell 12.2363 3.61309 1.942198e-01 0.52311127 DataSet_03_398
VWA3A JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 2.66667 1.41504 1.969501e-01 0.3942892 DataSet_03_403
VWA3A TFAP2A knockout Embryo H9 1.76471 0.819428 1.370630e-01 0.27304180 DataSet_03_405
VWA3A SATB2 CRISPR Colon Colon organoid 2.66667 1.41504 4.557441e-01 0.96954396 DataSet_03_406
VWA3A STRAP knockout Nerve SK-N-AS 0.144169 -2.79417 - - DataSet_03_409
VWA3A ZKSCAN3 CRISPR Colon HCT116 1.7 0.765535 1.818803e-01 0.614857172 DataSet_03_415
VWA3A FOXK2 shRNA Ovary OVCAR-5 3.33333 1.73697 3.406538e-02 0.14993555 DataSet_03_419
VWA3A BRD4 CRISPR Lymph CD8+ T cells 2.85714 1.51457 - - DataSet_03_420
VWA3A PRDM1 CRISPR Lymph CD8+ T cells 1.57143 0.652077 - - DataSet_03_421
VWA3A FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.6625 -0.594008 - - DataSet_03_422
VWA3A MAEL CRISPR Liver Alexander cells 2 1 - - DataSet_03_423
VWA3A FOXP3 CRISPR Peripheral_blood Naive Treg 0.571429 -0.807355 3.416937e-01 0.666366628 DataSet_03_427
VWA3A LHX2 shRNA Bone_marrow ES-derived RPE cells 0.5 -1 6.572623e-01 1.000000e+00 DataSet_03_428
VWA3A USP7 shRNA Skin xenograft cells 0.474683 -1.07496 0.26369300 0.4348960 DataSet_03_431
VWA3A PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 1.66667 0.736966 - - DataSet_03_432
VWA3A POU2AF1 CRISPR Lymph SUDHL4 2.78138 1.4758 2.371320e-01 0.415404129 DataSet_03_435
VWA3A EP300 knockout Pancreas HPAF-II orthotopic cells 0.506544 -0.981239 4.234978e-01 6.160894e-01 DataSet_03_436
VWA3A SUFU shRNA Mammary_gland HCC1954 cells 6 2.58496 0.4764545635 0.7691935 DataSet_03_437
VWA3A FOSL1 siRNA Prostate MSKPCa3 0.5 -1 0.0621091164 0.4571758 DataSet_03_445
VWA3A CBX2 siRNA Mammary_gland MCF7 6.62813 2.7286 2.645501e-01 0.4157485759 DataSet_03_451
VWA3A PPARG siRNA Aortic_valve Valvular endothelial cell 0.555556 -0.847997 6.281545e-01 8.704240e-01 DataSet_03_456
VWA3A HAND1 siRNA Placenta HPMVEC 0.535714 -0.900464 1.114119e-01 0.9463341 DataSet_03_459
VWA3A SOX9 knockout Liver HuH7 3 1.58496 3.300835e-01 4.505005e-01 DataSet_03_463
VWA3A PARP1 knockout Embryo_kidney HEK293a 5 2.32193 1.999274e-04 1.197096e-03 DataSet_03_464
VWA3A SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 17.4 4.12102 - - DataSet_03_467
VWA3A SMARCA1 shRNA Embryo_kidney HEK293T 4.4 2.1375 - - DataSet_03_468
VWA3A LIN28A siRNA Mammary_gland MCF7M 0.501142 -0.99671 3.318343e-01 0.7059059 DataSet_03_469
VWA3A LIN28A siRNA Mammary_gland MCF7M 0.501142 -0.99671 3.318343e-01 0.7059059 DataSet_03_470
VWA3A EZH2 siRNA Umbilical_vein HUVEC 2 1 5.498224e-02 0.268503412 DataSet_03_473
VWA3A CREBBP CRISPR Lymph U2932 1.66667 0.736966 1.228259e-01 1.0000000 DataSet_03_474
VWA3A EZH2 siRNA Prostate LNCaP 0.388889 -1.36257 4.264620e-01 1.0000000 DataSet_03_475
VWA3A APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.238095 -2.07039 0.1768372 0.6286134 DataSet_04_072
VWA3A CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.166667 -2.58496 0.6011382 0.745469757 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate YBX1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of VWA3A
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines