Gene Overview
Target Gene: ZNF704
NCBI Official Symbol: ZNF704
Entrez ID: 619279
Ensembl ID: ENSG00000164684
Gene Full Name: zinc finger protein 704
Strand: -
Gene Locus: 8q21.13
External Links:

ZNF704 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate ZNF704   
T(co)Fs that Repress ZNF704
The Intensity of the Gene Regulated by T(co)Fs:
ZNF704-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
ZNF704 IRF2 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 0.62678 -0.67396 0.00021 0.02267 DataSet_01_100
ZNF704 MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 0.60328 -0.72911 6.19585e-07 9.17409e-06 DataSet_01_102
ZNF704 HNF1B shRNA Ovary RMG2 2.42467 1.27779 0.00014 0.00084 DataSet_01_103
ZNF704 ID1 siRNA Lung A549 2.8493 1.51061 0.00515 0.11792 DataSet_01_117
ZNF704 ID1 siRNA Lung H1650 2.42733 1.27937 0.02244 0.33588 DataSet_01_118
ZNF704 BRD4 shRNA Embryo_kidney HEK293 0.64322 -0.63662 - - DataSet_01_119
ZNF704 ZIC2 siRNA Pancreas PANC1 0.49834 -1.0048 - - DataSet_01_121
ZNF704 FOXM1 siRNA Central_nervous_system U87 0.11238 -3.15351 - - DataSet_01_122
ZNF704 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.98606 0.98991 0.06158 0.72634 DataSet_01_137
ZNF704 SF1 siRNA Adrenal_gland H295R/TR 0.6459 -0.63062 3.2531e-05 0.00119 DataSet_01_146
ZNF704 ELK1 siRNA Peripheral_blood CD4+ T cells 0.45179 -1.14629 0.00276 0.02188 DataSet_01_162
ZNF704 JUN siRNA Peripheral_blood CD4+ T cells 0.4416 -1.17919 0.0041 0.03866 DataSet_01_164
ZNF704 MAF siRNA Peripheral_blood CD4+ T cells 0.23596 -2.08339 8.13385e-06 0.00137 DataSet_01_165
ZNF704 NFATC3 siRNA Peripheral_blood CD4+ T cells 0.29958 -1.73896 4.94284e-05 0.00561 DataSet_01_166
ZNF704 GATA2 siRNA Prostate LNCaP 0.60222 -0.73164 0.02463 0.0692 DataSet_01_193
ZNF704 TP63 siRNA Immortalized_keratinocyte HaCaT RG 1.90308 0.92834 - - DataSet_01_197
ZNF704 TP63 siRNA Immortalized_keratinocyte HaCaT 1.70264 0.76778 - - DataSet_01_200
ZNF704 TP63 siRNA Head_and_neck SCC-012 1.65527 0.72706 - - DataSet_01_201
ZNF704 MITF shRNA Skin COLO829 0.46408 -1.10757 0.00099 0.02181 DataSet_01_207
ZNF704 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 2.83106 1.50134 - - DataSet_01_209
ZNF704 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.62218 -0.68459 - - DataSet_01_210
ZNF704 LIN28A siRNA Embryo H9 1.57018 0.65093 0.01237 0.05606 DataSet_01_215
ZNF704 FOXC2 siRNA Lymph Lymphatic endothelial cells 1.96298 0.97305 0.00018 0.19196 DataSet_01_236
ZNF704 GATA6 siRNA Colon HT29 1.74981 0.8072 - - DataSet_01_247
ZNF704 ZIC5 siRNA Skin SK-MEL-28 1.69962 0.76522 - - DataSet_01_285
ZNF704 NFYA shRNA Lung H322 0.49919 -1.00233 1.98102e-05 0.00067 DataSet_01_288
ZNF704 TFAP4 siRNA Brain BE(2)-C 0.22052 -2.18103 0.37109 0.51625 DataSet_01_295
ZNF704 MYCN siRNA Brain BE(2)-C 1.58091 0.66076 0.92678 1 DataSet_01_296
ZNF704 SOX7 siRNA Umbilical_vein HUVEC 1.68811 0.75541 0.08832 0.89788 DataSet_01_299
ZNF704 SOX17 siRNA Umbilical_vein HUVEC 1.99117 0.99362 0.03035 0.99998 DataSet_01_300
ZNF704 PTEN shRNA Skin A431 1.64824 0.72093 0.00742 0.08696 DataSet_01_301
ZNF704 FOXO1 shRNA Haematopoietic_and_lymphoid_tissue RS4;11 0.60835 -0.71703 0.00196 0.03983 DataSet_01_321
ZNF704 TOX shRNA Haematopoietic_and_lymphoid_tissue CCRF-CEM 0.40909 -1.2895 9.96219e-05 0.33729 DataSet_01_331
ZNF704 HIF1A siRNA Oral_cavity OEC-M1 1.75067 0.8079 0.02528 0.85151 DataSet_01_348
ZNF704 CDX2 siRNA Colon COLO320 0.46185 -1.11451 - - DataSet_01_357
ZNF704 SOX17 siRNA Umbilical_vein HUVEC 1.97849 0.9844 - - DataSet_01_360
ZNF704 GTF2B siRNA Cervix HeLa 1.56603 0.64711 - - DataSet_01_362
ZNF704 SAFB2 shRNA Liver HepG2 0.585 -0.77349 0.01278 0.04601 DataSet_02_102
ZNF704 ZNF622 shRNA Liver HepG2 0.59137 -0.75787 0.00174 0.01059 DataSet_02_108
ZNF704 BCLAF1 shRNA Liver HepG2 0.57639 -0.79489 0.01513 0.06059 DataSet_02_112
ZNF704 PCBP1 shRNA Liver HepG2 1.77437 0.82731 0.00175 0.01526 DataSet_02_115
ZNF704 TARDBP shRNA Liver HepG2 0.58624 -0.77043 0.02884 0.07033 DataSet_02_116
ZNF704 HNRNPLL shRNA Liver HepG2 0.50748 -0.97858 0.00155 0.01443 DataSet_02_125
ZNF704 ZFX siRNA Prostate C4-2B 0.56203 -0.83128 0.00296 0.01322 DataSet_02_172
ZNF704 ARID1A siRNA Mammary_gland MDA-MB-157 1.54404 0.626711 - - DataSet_03_014
ZNF704 HIC1 CRISPR Prostate PC3 0.654936 -0.610574 - - DataSet_03_118
ZNF704 JARID1A siRNA Autonomic_ganglia SKNBE2 1.74843 0.806062 0.00252062300455548 0.191653934632633 DataSet_03_135
ZNF704 MEF2D shRNA Liver HuH7 0.552675 -0.855496 - - DataSet_03_162
ZNF704 MITF siRNA Skin MZ7 0.531743 -0.911199 3.53289722268638e-08 8.25945662020763e-07 DataSet_03_165
ZNF704 MITF siRNA Skin SK-MEL-5 0.466731 -1.09934 1.69383542871734e-06 2.39819390848061e-05 DataSet_03_168
ZNF704 MYC siRNA Colon HT29 2.54638 1.34845 - - DataSet_03_177
ZNF704 NFKB1 siRNA Central_nervous_system U251 0.623506 -0.681524 0.00187215179372422 0.0190445559728839 DataSet_03_197
ZNF704 NR4A3 siRNA Pancreas 1.1B4 3.0164 1.59283 1.89072769422611e-06 4.64020364358237e-05 DataSet_03_203
ZNF704 PHB shRNA Embryo Embryonic stem cells (ESCs) 2.11624 1.0815 0.00225307394909927 0.0101625320491032 DataSet_03_211
ZNF704 SOX11 siRNA Lung_fibroblast NHLF 0.481375 -1.05477 0.284009420002404 0.612273876569061 DataSet_03_237
ZNF704 SOX2 siRNA Embryo 2102Ep 1.85197 0.88906 0.00010698920621887 0.00374617181763559 DataSet_03_242
ZNF704 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 1.64444 0.7176 - - DataSet_03_246
ZNF704 STAT3 CRISPR Embryo hESC 4.1846 2.06509 0.0326488717430531 0.102395618269811 DataSet_03_258
ZNF704 TFAP2C siRNA Mammary_gland MCF7 0.616879 -0.696942 0.0550807971850675 0.385402259687002 DataSet_03_274
ZNF704 TFE3 siRNA Kidney UOK257-2 1.77654 0.829073 - - DataSet_03_275
ZNF704 ZNF746 siRNA Colon HCT116 0.52015 -0.943 - - DataSet_03_293
ZNF704 YBX1 CRISPR Liver HepG2 0.660346 -0.598705 0.102344345768311 0.972884761036538 DataSet_04_039
ZNF704 ABT1 shRNA Liver HepG2 0.496943 -1.00885 0.000741735350636945 0.006998860747062 DataSet_04_052
ZNF704 CALR shRNA Liver HepG2 0.466895 -1.09883 0.000245275094415124 0.00511707114702432 DataSet_04_053
ZNF704 CNOT7 shRNA Liver HepG2 0.489691 -1.03006 0.000950721144993948 0.00664440267874465 DataSet_04_051
ZNF704 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 6.36842 2.67094 0.329704453712407 0.589752079499267 DataSet_02_38
ZNF704 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.0263158 -5.24793 0.251077244775933 0.419612267970946 DataSet_02_34
ZNF704 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.394737 -1.34104 0.430954735708637 0.660791994151468 DataSet_02_32
ZNF704 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.63158 0.706269 0.419143048146525 0.579809522431551 DataSet_02_47
ZNF704 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.447368 -1.16046 0.545323055725224 0.69956782399314 DataSet_02_53
ZNF704 CNOT3 shRNA Lung A549 0.647098 -0.627944 1.101253e-01 0.8830540 DataSet_03_340
ZNF704 EZH2 shRNA Colon SW480 2.46473 1.30143 - - DataSet_03_298
ZNF704 SMARCA4 siRNA Colon HCT116 1.59757 0.675877 2.317146e-01 9.892536e-01 DataSet_03_301
ZNF704 ELF3 CRISPR Bile_duct HBDEC2 0.338677 -1.56202 1.427603e-03 7.948163e-03 DataSet_03_304
ZNF704 ELF3 knockdown Bile_duct HBDEC2 0.458046 -1.12643 8.456371e-02 2.642232e-01 DataSet_03_305
ZNF704 ACTR5 siRNA Muscle RD 0.655128 -0.61015 - - DataSet_03_343
ZNF704 EZH2 knockdown Colon HCT116 0.395545 -1.33809 0.308369457 0.9301183 DataSet_03_334
ZNF704 ARID3B CRISPR Colon HCT15 0.643573 -0.635825 - - DataSet_03_335
ZNF704 TET1 CRISPR Mammary_gland MDA-MB-231 5.1321 2.35955 1.055837e-01 2.733736e-01 DataSet_03_347
ZNF704 ZFX siRNA Prostate C4-2B 0.547548 -0.868941 6.797785e-07 3.583055e-05 DataSet_03_348
ZNF704 ZFX siRNA Mammary_gland MCF7 0.516836 -0.952221 2.381436e-05 1.487805e-03 DataSet_03_349
ZNF704 SKI CRISPR Blood HL60 0.0212454 -5.5567 4.534750e-07 0.003512680 DataSet_03_351
ZNF704 TET1 CRISPR Mammary_gland Hs578T 0.460807 -1.11776 2.201346e-05 2.345391e-03 DataSet_03_355
ZNF704 CREBBP CRISPR Brain U5-NPC 1.66667 0.736966 0.6508931918 0.7766311 DataSet_03_356
ZNF704 PTPN14 CRISPR Brain U5-NPC 0.5 -1 2.249523e-01 0.44626712 DataSet_03_357
ZNF704 TP53 CRISPR Brain U5-NPC 1.63768 0.711654 7.375307e-01 7.987799e-01 DataSet_03_358
ZNF704 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 0.441549 -1.17936 5.010496e-01 7.250918e-01 DataSet_03_359
ZNF704 EP300 shRNA Mammary_gland MCF10AT 3.91453 1.96884 7.686213e-04 0.019179932 DataSet_03_364
ZNF704 DNMT3A knockout Embryo_kidney HEK293T 0.344228 -1.53856 - - DataSet_03_369
ZNF704 ZFP36L1 siRNA Urinary_bladder J82 1.66667 0.736966 - - DataSet_03_371
ZNF704 E2F1 siRNA Nasopharynx HK1 1.75761 0.813612 2.806134e-01 9.722824e-01 DataSet_03_373
ZNF704 HNRNPU siRNA Colon RKO 0.574206 -0.800359 - - DataSet_03_374
ZNF704 EZH2 CRISPR Ovary SKOV3 1.84463 0.883329 5.321807e-03 0.0529277623 DataSet_03_378
ZNF704 DDX5 shRNA Stomach HGC-27 0.548673 -0.865983 - - DataSet_03_379
ZNF704 NFKB2 siRNA Bone_marrow U2OS 0.570193 -0.810477 5.049172e-02 0.29260110 DataSet_03_381
ZNF704 DNMT1 siRNA Skin Human melanoma cells 0.455144 -1.1356 1.478264e-05 1.379103e-04 DataSet_03_382
ZNF704 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 2.35774 1.2374 0.6188598968 0.9227643 DataSet_03_387
ZNF704 TRIM8 siRNA Mammary_gland MCF7 0.462049 -1.11388 9.786328e-04 0.0126574761 DataSet_03_388
ZNF704 NFKBIA shRNA Bone_marrow U2OS 0.613239 -0.705479 2.729584e-01 0.87005461 DataSet_03_389
ZNF704 YY1 knockdown Liver HepG2 2.30241 1.20314 3.312773e-09 1.153457e-07 DataSet_03_390
ZNF704 ILF2 siRNA Stomach SGC-7901 5.69231 2.50901 0.1029251036 0.25965043 DataSet_03_393
ZNF704 IKZF2 CRISPR Lymph CAR T Cell 3.07547 1.62081 4.149344e-02 0.403599120 DataSet_03_397
ZNF704 RELA CRISPR Brain T30 0.0722649 -3.79056 0.2977608378 0.8400824 DataSet_03_399
ZNF704 EHF shRNA Stomach MKN7 0.134454 -2.89482 - - DataSet_03_402
ZNF704 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.80386 0.851086 4.283530e-01 0.5747889 DataSet_03_403
ZNF704 CDK7 shRNA Bone_marrow D458 0.556662 -0.845127 4.434771e-02 0.30154055 DataSet_03_404
ZNF704 SIRT1 siRNA Pancreas PANC1 0.520833 -0.941106 1.702036e-02 0.068560723 DataSet_03_410
ZNF704 USP22 shRNA Liver HuH7 5.59648 2.48452 - - DataSet_03_411
ZNF704 E2F6 shRNA Liver HuH7 0.613593 -0.704647 - - DataSet_03_412
ZNF704 ZKSCAN3 CRISPR Colon HCT116 0.451146 -1.14833 1.112183e-01 0.499475608 DataSet_03_415
ZNF704 RUNX2 shRNA Cord_blood Natural Killer Cell 0.26087 -1.9386 2.630183e-01 0.793390621 DataSet_03_416
ZNF704 FOXQ1 CRISPR Lymph Primary CD4+ T cells 5.38835 2.42984 - - DataSet_03_422
ZNF704 MAEL CRISPR Liver Alexander cells 0.2 -2.32193 - - DataSet_03_423
ZNF704 FOXP3 CRISPR Peripheral_blood Naive Treg 0.0656566 -3.92892 6.727899e-02 0.353849144 DataSet_03_427
ZNF704 LHX2 shRNA Bone_marrow ES-derived RPE cells 0.385417 -1.37551 3.218813e-02 1.000000e+00 DataSet_03_428
ZNF704 USP7 shRNA Skin xenograft cells 0.406627 -1.29822 0.26076186 0.4348960 DataSet_03_431
ZNF704 EP300 knockout Pancreas HPAF-II orthotopic cells 0.307371 -1.70194 4.814350e-06 2.435672e-04 DataSet_03_436
ZNF704 SUFU shRNA Mammary_gland HCC1954 cells 0.603596 -0.728345 0.0758599719 0.5891146 DataSet_03_437
ZNF704 CIC knockout Brain Immortalized Astrocyte Cells 9.8013 3.29297 5.220500e-02 3.907729e-01 DataSet_03_438
ZNF704 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.620165 -0.689276 5.328175e-01 0.95277069 DataSet_03_439
ZNF704 SETDB1 shRNA Colon HCT116 0.189729 -2.39799 - - DataSet_03_440
ZNF704 DAXX shRNA Mammary_gland MDA-MB-231 3.79599 1.92448 5.619586e-01 0.80142090 DataSet_03_441
ZNF704 PURA siRNA Cervix HeLa 1.53432 0.617602 3.064369e-02 0.158107340 DataSet_03_444
ZNF704 CAMTA1 knockout Embryo_kidney HEK293T 1.62749 0.702645 1.639259e-02 0.12165069 DataSet_03_448
ZNF704 CBX2 siRNA Mammary_gland MDA-MB-231 1.85372 0.890422 4.443583e-01 6.613933e-01 DataSet_03_450
ZNF704 CBX2 siRNA Mammary_gland MCF7 1.66014 0.731301 4.698699e-02 0.1032174219 DataSet_03_451
ZNF704 SMARCA2 shRNA Lung HCC2302 0.469381 -1.09117 1.341388e-05 2.802044e-05 DataSet_03_455
ZNF704 TXNIP shRNA Cord_Blood CD34+ cells 3.19802 1.67718 - - DataSet_03_461
ZNF704 TXNIP shRNA Cord_blood ST3 4.71233 2.23644 4.942678e-03 0.1161694323 DataSet_03_462
ZNF704 SOX9 knockout Liver HuH7 0.402119 -1.3143 2.212996e-04 3.479878e-03 DataSet_03_463
ZNF704 STAT3 shRNA Liver HepG2 1.54437 0.627019 6.963358e-02 0.3967514505 DataSet_03_465
ZNF704 SMARCA1 Cas13 Embryo_kidney HEK293T 0.30991 -1.69008 - - DataSet_03_466
ZNF704 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.51712 0.601332 - - DataSet_03_467
ZNF704 EZH2 siRNA Prostate LNCaP 1.66344 0.734169 - - DataSet_03_472
ZNF704 CREBBP CRISPR Lymph U2932 1.73333 0.793549 4.610244e-01 1.0000000 DataSet_03_474
Regulation Region
 
T(co)Fs that significantly regulate ERF by the evidences of both expression and ChIP-seq/motif
Expression Atlas of ZNF704
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines