Welcome to ENdb!

An experimentally supported enhancer database for human and mouse, curated from thousands of published literatures.

What is ENdb?

An Experimentally Supported Enhancer Database

Here, we introduce ENdb 2.0 (http://www.licpathway.net/ENdb), an updated and significantly expanded database, which newly documents 2,003 experimentally validated enhancer interactions and 741 diseases/phenotypes through manually curating of over 20,000 published literature. Through reviewing 5,518 published literatures, the current release of ENdb 2.0 documents 2,003 experimentally validated enhancers and their related information, including: 776 cell names, 267 tissue names, 969 target genes, 556 transcription factors, and 141 SNPs. In addition, ENdb 2.0 provides a user-friendly interface for searching, browsing, and visualizing enhancer-related information, and integrates a genome browser based on JBrowse2 for displaying enhancer genomic locations.

Statistics

Key data metrics of ENdb 2.0

5,518
Papers Reviewed
2,003
Enhancers
741
Diseases / Phenotypes
969
Target Genes
556
Transcription Factors
141
SNPs
776
Cell Types
267
Tissue Types
ENdb Overview

Sister Projects

Explore related databases developed by our team

TF-Marker database for human transcription factor markers
Documenting a large number of available resources of mammalian transcription co-factors
SEdb: The comprehensive human Super-Enhancer database

Ready to Explore Enhancers?

Search our database of 2,003 experimentally validated enhancers across human and mouse genomes.

Go to Search