An experimentally supported enhancer database for human and mouse, curated from thousands of published literatures.
Here, we introduce ENdb 2.0 (http://www.licpathway.net/ENdb), an updated and significantly expanded database, which newly documents 2,003 experimentally validated enhancer interactions and 741 diseases/phenotypes through manually curating of over 20,000 published literature. Through reviewing 5,518 published literatures, the current release of ENdb 2.0 documents 2,003 experimentally validated enhancers and their related information, including: 776 cell names, 267 tissue names, 969 target genes, 556 transcription factors, and 141 SNPs. In addition, ENdb 2.0 provides a user-friendly interface for searching, browsing, and visualizing enhancer-related information, and integrates a genome browser based on JBrowse2 for displaying enhancer genomic locations.
Key data metrics of ENdb 2.0
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