About Enhancer
| Enhancer ID: | E_00008 |
| Species: | Mus musculus |
| Position : | chr5:28395077-28395877   |
| Year: | 2005 |
| Title: | Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 15677727 |
| Tissue: | limb |
| Tissue Ontology ID: | UBERON:0002101 |
| Cell Source: | mouse embryonic limb bud |
| Experiment Type: | Endogenous enhancer deletion; transgenic reporter; in vivo developmental phenotyping |
| Low Throughput Method: | Targeted deletion in mouse; transgenic reporter assay; Shh expression analysis; skeletal phenotyping |
About Target Gene
| Target gene : | Shh |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02535 | chr5:28395077-28395877 | forelimb bud | mesenchymal cell | NA |
Expression of Target Genes for the Enhancer