Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00010
Species: Mus musculus
Position : chrX:92344753-92346405
Year: 2018
Title: Ultraconserved Enhancers Are Required for Normal Development
Genome Build: mm39
Enhancer Type: Enhancer
Condition: Normal
PMID:  29358049
Tissue: forebrain
Tissue Ontology ID: UBERON:0001890
Cell Source: mouse embryonic forebrain
Experiment Type: Endogenous enhancer knockout; single and combinatorial enhancer deletion; neurodevelopmental phenotyping
High Throughput Method: Single-cell transcriptomic profiling (Drop-seq) and expression profiling in selected enhancer-mutant tissues
Low Throughput Method: CRISPR/genome-edited mouse enhancer deletion; histology; neuronal population analysis; structural brain phenotyping; developmental reporter evidence
About Target Gene
Target gene : Arx
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm39)
No overlapping enhancers found in mm39 at this locus.
Expression of Target Genes for the Enhancer