About Enhancer
| Enhancer ID: | E_00033 |
| Species: | Homo sapiens |
| Position : | chr8:209981000-209990000   |
| Year: | 2016 |
| Title: | Systematic mapping of functional enhancer-promoter connections with CRISPR interference |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Acute myeloid leukemia |
| PMID: | 27708057 |
| MONDO: | MONDO:0018874 |
| Tissue: | Bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | K562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | Human erythroleukemia cell line |
| Cell Ontology ID: | CL:0009084 |
| Experiment Type: | CRISPRi interference, clonal genomic deletion, Hi-C chromatin contact validation |
| High Throughput Method: | DNase-seq, H3K27ac ChIP-seq, RNA-seq, Pol II ChIA-PET, Hi-C |
| Low Throughput Method: | RT-qPCR, clonal cell line generation, sgRNA lentiviral transduction, cell viability assay |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00034 | chr8:209981000-209990000 | Bone marrow | Human erythroleukemia cell line | Erythroleukemia |
Expression of Target Genes for the Enhancer