About Enhancer
| Enhancer ID: | E_00089 |
| Species: | Homo sapiens |
| Position : | chr17:5958900-5960100   |
| Year: | 2025 |
| Title: | Systematic decoding of functional enhancer connectomes and risk variants in human glioma |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Glioblastoma multiforme |
| PMID: | 40830415 |
| MONDO: | MONDO:0001628 |
| Tissue: | Brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | U251 |
| CVCL ID: | CVCL_0021 |
| Cell Type: | glioma cell line |
| Cell Ontology ID: | CL:0000917 |
| Experiment Type: | dCas9-KRAB CRISPRi, HiChIP chromatin looping validation, 3C-qPCR |
| High Throughput Method: | H3K27ac HiChIP, H3K27ac ChIP-seq, ATAC-seq, RNA-seq, pooled CRISPRi screening |
| Low Throughput Method: | qRT-PCR, MTT cell proliferation assay |
About Target Gene
| Target gene : | VMP1 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer