Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00094
Species: Mus musculus
Position : chr11:32150550-32151858
Year: 2016
Title: Genetic dissection of the 汐-globin super-enhancer in vivo.
Genome Build: mm9
Enhancer Type: Enhancer
Condition: Normal
PMID:  27376235
Tissue: liver
Tissue Ontology ID: UBERON:0002107
Cell Source: Primary mouse fetal liver erythroid cells
Cell Type: erythroblast
Cell Ontology ID: CL:0000765
Experiment Type: Super-enhancer constituent functional dissection; TF binding assay; Functional perturbation assay; In vivo functional validation
High Throughput Method: DNase-seq; ChIP-seq; ATAC-seq; NG Capture-C; RNA-seq
Low Throughput Method: Targeted in vivo enhancer deletion; Southern blot; sequencing; transgenic/Citrine enhancer reporter assay; RT-qPCR; hematologic phenotyping; In vivo phenotyping
About Target Gene
Target gene : Hba-a1
About TF
TF name : Klf1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm9) 44 found
Enhancer ID Position Tissue Cell Disease
E_02494 chr11:32145540-32169344 NA primitive erythroid lineage cell NA
E_02495 chr11:32145540-32169344 NA primitive erythroid lineage cell NA
E_00076 chr11:32150550-32151858 liver erythroblast NA
E_00077 chr11:32150550-32151858 liver erythroblast NA
E_00078 chr11:32150550-32151858 liver erythroblast NA
E_00079 chr11:32150550-32151858 liver erythroblast NA
E_00080 chr11:32150550-32151858 liver erythroblast NA
E_00081 chr11:32150550-32151858 liver erythroblast NA
E_00082 chr11:32150550-32151858 liver erythroblast NA
E_00083 chr11:32150550-32151858 liver erythroblast NA
E_00092 chr11:32150550-32151858 liver erythroblast NA
E_00093 chr11:32150550-32151858 liver erythroblast NA
E_00095 chr11:32150550-32151858 liver erythroblast NA
E_00096 chr11:32150550-32151858 liver erythroblast NA
E_00097 chr11:32150550-32151858 liver erythroblast NA
E_00098 chr11:32150550-32151858 liver erythroblast NA
E_00099 chr11:32150550-32151858 liver erythroblast NA
E_00213 chr11:32150550-32151858 liver erythroblast NA
E_00214 chr11:32150550-32151858 liver erythroblast NA
E_00215 chr11:32150550-32151858 liver erythroblast NA
E_00216 chr11:32150550-32151858 liver erythroblast NA
E_00217 chr11:32150550-32151858 liver erythroblast NA
E_00218 chr11:32150550-32151858 liver erythroblast NA
E_00219 chr11:32150550-32151858 liver erythroblast NA
E_00220 chr11:32150550-32151858 liver erythroblast NA
E_00446 chr11:32150550-32151858 blood erythroid cell NA
E_00447 chr11:32150550-32151858 blood erythroid cell NA
E_00448 chr11:32150550-32151858 blood erythroid cell NA
E_00449 chr11:32150550-32151858 blood erythroid cell NA
E_02551 chr11:32150550-32151858 NA primitive erythroid lineage cell NA
E_02552 chr11:32150550-32151858 NA primitive erythroid lineage cell NA
E_02553 chr11:32150550-32151858 NA primitive erythroid lineage cell NA
E_02554 chr11:32150550-32151858 NA primitive erythroid lineage cell NA
E_02555 chr11:32150550-32151858 NA primitive erythroid lineage cell NA
E_02556 chr11:32150550-32151858 NA primitive erythroid lineage cell NA
E_02557 chr11:32150550-32151858 NA primitive erythroid lineage cell NA
E_02558 chr11:32150550-32151858 NA primitive erythroid lineage cell NA
E_03313 chr11:32150550-32151858 liver erythroid cell NA
E_03480 chr11:32150550-32151858 spleen erythroblast NA
E_03481 chr11:32150550-32151858 spleen erythroblast NA
E_03482 chr11:32150550-32151858 spleen erythroblast NA
E_03483 chr11:32150550-32151858 spleen erythroblast NA
E_03484 chr11:32150550-32151858 spleen erythroblast NA
E_03485 chr11:32150550-32151858 spleen erythroblast NA
Expression of Target Genes for the Enhancer