About Enhancer
| Enhancer ID: | E_00109 |
| Species: | Homo sapiens |
| Position : | chr13:73096200-73097010   |
| Year: | 2021 |
| Title: | Enhancer release and retargeting activates disease-susceptibility genes |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Melanoma |
| PMID: | 34040254 |
| MONDO: | MONDO:0005105 |
| Tissue: | Skin |
| Tissue Ontology ID: | UBERON:0000014 |
| Cell Source: | HEK293T |
| CVCL ID: | CVCL_0063 |
| Cell Type: | human embryonic kidney cell |
| Cell Ontology ID: | CL:0002139 |
| Experiment Type: | CRISPRi promoter inhibition, CRISPR-Cas9 SNP knock-in, 4C-seq chromatin looping |
| High Throughput Method: | H3K27ac ChIP-seq, whole-genome cancer mutation data |
| Low Throughput Method: | RT-qPCR, ChIP-qPCR for CTCF binding |
About Target Gene
| Target gene : | TERT |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00110 | chr13:73096200-73097010 | Lung | human embryonic kidney cell | Lung adenocarcinoma |
Expression of Target Genes for the Enhancer