About Enhancer
| Enhancer ID: | E_00111 |
| Species: | Homo sapiens |
| Position : | chr19:19942100-19942880   |
| Year: | 2021 |
| Title: | Enhancer release and retargeting activates disease-susceptibility genes |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | B-cell non-Hodgkin lymphoma |
| PMID: | 34040254 |
| MONDO: | MONDO:0018907 |
| Tissue: | Bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | MCF-7 |
| CVCL ID: | CVCL_0031 |
| Cell Type: | breast epithelial cell |
| Cell Ontology ID: | CL:0001070 |
| Experiment Type: | CRISPRi ZCCHC7 promoter silencing, Hi-C chromatin contact validation |
| High Throughput Method: | ATAC-seq, cancer WGS datasets |
| Low Throughput Method: | RT-qPCR gene expression quantification |
About Target Gene
| Target gene : | PAX5 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer