About Enhancer
| Enhancer ID: | E_00113 |
| Species: | Homo sapiens |
| Position : | chr1:205814100-205814900   |
| Year: | 2021 |
| Title: | Enhancer release and retargeting activates disease-susceptibility genes |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Parkinson's disease |
| PMID: | 34040254 |
| MONDO: | MONDO:0004773 |
| Tissue: | Brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | iPSC-derived NPC |
| CVCL ID: | |
| Cell Type: | neural progenitor cell |
| Cell Ontology ID: | CL:0000060 |
| Experiment Type: | dCas9-KRAB enhancer silencing, allele-specific 4C-seq, ChIP-qPCR CTCF binding |
| High Throughput Method: | scRNA-seq, H3K27ac ChIP-seq, GTEx eQTL profiling |
| Low Throughput Method: | RT-qPCR allelic expression assay |
About Target Gene
| Target gene : | RAB7L1 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer