About Enhancer
| Enhancer ID: | E_00115 |
| Species: | Homo sapiens |
| Position : | chr12:43108222-43108860   |
| Year: | 2024 |
| Title: | Multiplex single-cell CRISPRa screening for cell type specific regulatory elements |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Chronic myelogenous leukemia |
| PMID: | 39294132 |
| MONDO: | MONDO:0004990 |
| Tissue: | Bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | K562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | erythroleukemia cell |
| Cell Ontology ID: | CL:0001054 |
| Experiment Type: | CRISPRa gain-of-function perturbation, single-cell RNA-seq functional validation |
| High Throughput Method: | scRNA-seq, ATAC-seq, H3K27ac CUT&RUN, pooled CRISPR screening |
| Low Throughput Method: | bulk RNA-seq singleton validation, lentiviral gRNA transduction, RT-qPCR |
About Target Gene
| Target gene : | ASIC1 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer