About Enhancer
| Enhancer ID: | E_00116 |
| Species: | Homo sapiens |
| Position : | chr12:64791312-64791930   |
| Year: | 2024 |
| Title: | Multiplex single-cell CRISPRa screening for cell type specific regulatory elements |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 39294132 |
| MONDO: | |
| Tissue: | Brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | WTC11 iPSC-neuron |
| CVCL ID: | |
| Cell Type: | excitatory iPSC-derived neuron |
| Cell Ontology ID: | CL:0002358 |
| Experiment Type: | CRISPRa gain-of-function perturbation, single-cell RNA-seq validation |
| High Throughput Method: | scRNA-seq, neuronal ATAC-seq, H3K27ac CUT&RUN, pooled CRISPR screening |
| Low Throughput Method: | bulk RNA-seq singleton validation, iPSC differentiation, lentiviral transduction, RT-qPCR |
About Target Gene
| Target gene : | HMGA1 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer