About Enhancer
| Enhancer ID: | E_00152 |
| Species: | Homo sapiens |
| Position : | chr13:20993543-20994585   |
| Year: | 2022 |
| Title: | 3D Chromatin Organization Involving MEIS1 Factor in the cis-Regulatory Landscape of GJB2 |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 35805969 |
| MONDO: | |
| Tissue: | Embryonic Kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | HEK293T |
| CVCL ID: | CVCL_0063 |
| Cell Type: | embryonic kidney cell |
| Cell Ontology ID: | CL:0002139 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | 4C-seq, ChIP-seq, RNA-seq |
| Low Throughput Method: | CRISPRi, CRISPRa, ChIP-RT-qPCR, Luciferase reporter assay, RT-RT-qPCR |
About Target Gene
| Target gene : | GJB2 |
About TF
| TF name : | MEIS1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| MEIS1 | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer