About Enhancer
| Enhancer ID: | E_00163 |
| Species: | Homo sapiens |
| Position : | chr12:105800000-105801000   |
| Year: | 2020 |
| Title: | Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 32698000 |
| MONDO: | |
| Tissue: | Cranial neural crest |
| Tissue Ontology ID: | UBERON:0003099 |
| Cell Source: | hCNCC cells |
| CVCL ID: | |
| Cell Type: | cranial neural crest cell |
| Cell Ontology ID: | CL:0000333 |
| Experiment Type: | Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | Hi-C, ChIP-seq |
| Low Throughput Method: | CRISPRi, Luciferase Reporter Assay, RT-RT-qPCR |
About Target Gene
| Target gene : | NUAK1 |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer