Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00186
Species: Homo sapiens
Position : chr3:46453226-46459225
Year: 2025
Title: Enhancer transcription profiling reveals an enhancer RNA-driven ferroptosis and new therapeutic opportunities in prostate cancer
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: prostate cancer
PMID:  40082405
MONDO: MONDO:0008316
Tissue: prostate
Tissue Ontology ID: UBERON:0002367
Cell Type: prostate cancer cell
Experiment Type: integrated epigenomic analysis
High Throughput Method: ATAC-seq; RNA-seq; ChIP-seq (H3K27ac, H3K4me1)
Low Throughput Method: ChIP-qPCR; luciferase reporter assay; 3C-qPCR; RNA-FISH; ChIRP; RIP-qPCR; western blot
About Target Gene
Target gene : LTF
About TF
TF name : NR
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 3 found
Enhancer ID Position Tissue Cell Disease
E_01320 chr3:46453226-46459225 Prostate prostate carcinoma cell prostate cancer
E_01321 chr3:46453226-46459225 Prostate prostate carcinoma cell prostate cancer
E_01322 chr3:46453226-46459225 Prostate prostate epithelial cell --
Expression of Target Genes for the Enhancer