Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00211
Species: Mus musculus
Position : chr11:32145028-32146147
Year: 2016
Title: Genetic dissection of the 汐-globin super-enhancer in vivo.
Genome Build: mm9
Enhancer Type: Enhancer
Condition: Normal
PMID:  27376235
Tissue: liver
Tissue Ontology ID: UBERON:0002107
Cell Source: Primary mouse fetal liver erythroid cells
Cell Type: erythroblast
Cell Ontology ID: CL:0000765
Experiment Type: Enhancer activity assay; TF binding assay; Chromatin interaction assay; Functional perturbation assay; In vivo functional validation
High Throughput Method: DNase-seq; ChIP-seq; ATAC-seq; NG Capture-C; RNA-seq
Low Throughput Method: Targeted in vivo enhancer deletion; Southern blot; sequencing; RT-qPCR; hematologic phenotyping; In vivo phenotyping
About Target Gene
Target gene : Hba-a1
About TF
TF name : Tal1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm9) 44 found
Enhancer ID Position Tissue Cell Disease
E_00068 chr11:32145028-32146147 liver erythroblast NA
E_00069 chr11:32145028-32146147 liver erythroblast NA
E_00070 chr11:32145028-32146147 liver erythroblast NA
E_00071 chr11:32145028-32146147 liver erythroblast NA
E_00072 chr11:32145028-32146147 liver erythroblast NA
E_00073 chr11:32145028-32146147 liver erythroblast NA
E_00074 chr11:32145028-32146147 liver erythroblast NA
E_00075 chr11:32145028-32146147 liver erythroblast NA
E_00084 chr11:32145028-32146147 liver erythroblast NA
E_00085 chr11:32145028-32146147 liver erythroblast NA
E_00086 chr11:32145028-32146147 liver erythroblast NA
E_00087 chr11:32145028-32146147 liver erythroblast NA
E_00088 chr11:32145028-32146147 liver erythroblast NA
E_00089 chr11:32145028-32146147 liver erythroblast NA
E_00090 chr11:32145028-32146147 liver erythroblast NA
E_00091 chr11:32145028-32146147 liver erythroblast NA
E_00205 chr11:32145028-32146147 liver erythroblast NA
E_00206 chr11:32145028-32146147 liver erythroblast NA
E_00207 chr11:32145028-32146147 liver erythroblast NA
E_00208 chr11:32145028-32146147 liver erythroblast NA
E_00209 chr11:32145028-32146147 liver erythroblast NA
E_00210 chr11:32145028-32146147 liver erythroblast NA
E_00212 chr11:32145028-32146147 liver erythroblast NA
E_00442 chr11:32145028-32146147 blood erythroid cell NA
E_00443 chr11:32145028-32146147 blood erythroid cell NA
E_00444 chr11:32145028-32146147 blood erythroid cell NA
E_00445 chr11:32145028-32146147 blood erythroid cell NA
E_02543 chr11:32145028-32146147 NA primitive erythroid lineage cell NA
E_02544 chr11:32145028-32146147 NA primitive erythroid lineage cell NA
E_02545 chr11:32145028-32146147 NA primitive erythroid lineage cell NA
E_02546 chr11:32145028-32146147 NA primitive erythroid lineage cell NA
E_02547 chr11:32145028-32146147 NA primitive erythroid lineage cell NA
E_02548 chr11:32145028-32146147 NA primitive erythroid lineage cell NA
E_02549 chr11:32145028-32146147 NA primitive erythroid lineage cell NA
E_02550 chr11:32145028-32146147 NA primitive erythroid lineage cell NA
E_03320 chr11:32145028-32146147 liver erythroid cell NA
E_03474 chr11:32145028-32146147 spleen erythroblast NA
E_03475 chr11:32145028-32146147 spleen erythroblast NA
E_03476 chr11:32145028-32146147 spleen erythroblast NA
E_03477 chr11:32145028-32146147 spleen erythroblast NA
E_03478 chr11:32145028-32146147 spleen erythroblast NA
E_03479 chr11:32145028-32146147 spleen erythroblast NA
E_02494 chr11:32145540-32169344 NA primitive erythroid lineage cell NA
E_02495 chr11:32145540-32169344 NA primitive erythroid lineage cell NA
Expression of Target Genes for the Enhancer