About Enhancer
| Enhancer ID: | E_00228 |
| Species: | Homo sapiens |
| Position : | chr12:6448000-6450000   |
| Year: | 2025 |
| Title: | Evidence for enhancer activity in intron 1 of TNFRSF1A using CRISPR/Cas9 in human induced pluripotent stem cell-derived macrophages |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 41057395 |
| MONDO: | |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | CD4+ T cells |
| CVCL ID: | |
| Cell Type: | CD4-positive T cell |
| Cell Ontology ID: | CL:0000624 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ATAC-seq, ChIP-seq, RNA-seq, Capture-C |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPR Knockout, CRISPRi, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | TNFRSF1A |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00229 | chr12:6448000-6450000 | Blood | CD8-positive T cell | -- |
Expression of Target Genes for the Enhancer