About Enhancer
| Enhancer ID: | E_00232 |
| Species: | Homo sapiens |
| Position : | chr8:128320000-128322000   |
| Year: | 2014 |
| Title: | Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | colorectal cancer |
| PMID: | 24662484 |
| MONDO: | MONDO:0005176 |
| Tissue: | Colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | HCT116 |
| CVCL ID: | CVCL_0291 |
| Cell Type: | colorectal carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, 3C-seq, RNA-seq |
| Low Throughput Method: | 3C, Luciferase Reporter Assay, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | CTCF; TCF7L2; MED1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
6 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00378 | chr8:128230503-128380503 | Colon | colorectal carcinoma cell | colorectal carcinoma |
| E_00379 | chr8:128230503-128380503 | Colon | colorectal carcinoma cell | colorectal carcinoma |
| E_00908 | chr8:128311200-128667652 | Brain | medulloblastoma cell | medulloblastoma |
| E_00828 | chr8:128320000-128321000 | Colon | colorectal carcinoma cell | colorectal carcinoma |
| E_00793 | chr8:128320500-128321500 | Colon | colorectal carcinoma cell | colorectal carcinoma |
| E_00421 | chr8:128322000-128323000 | Colon | colorectal carcinoma cell | colorectal carcinoma |
Expression of Target Genes for the Enhancer